Brigitte Hertel
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View article: Microfluidically Produced Microcapsules with Amphiphilic Polymer Conetwork Shells
Microfluidically Produced Microcapsules with Amphiphilic Polymer Conetwork Shells Open
Microcapsules with an aqueous core can be conveniently prepared by water‐in‐oil‐in‐water double emulsion microfluidics. However, conventional shell materials are based on hydrophobic polymers or colloidal particles. Thus, these microcapsul…
View article: Self-Decorating Cells Via Surface-Initiated Enzymatic Controlled Radical Polymerizations
Self-Decorating Cells Via Surface-Initiated Enzymatic Controlled Radical Polymerizations Open
Innovatively utilizing surface-displayed horseradish peroxidase, this paper explores the enzymatic catalysis of both bioRAFT polymerization and bioATRP to prompt polymer synthesis on the surface of Saccharomyces cerevisiae cells, with bioA…
View article: Microfluidically produced microcapsules with amphiphilic polymer conetwork shells
Microfluidically produced microcapsules with amphiphilic polymer conetwork shells Open
Microcapsules with aqueous core can be conveniently prepared by water-in-oil-in-water double emulsion microfluidics. However, conventional shell materials are either based on polymers or monomers that are soluble in the oil phase, or based…
View article: Self-decorating cells <i>via</i> surface-initiated enzymatic controlled radical polymerization
Self-decorating cells <i>via</i> surface-initiated enzymatic controlled radical polymerization Open
Through the use of surface-displayed horseradish peroxidase, this work explores the enzymatic catalysis of both bioRAFT and bioATRP to prompt polymer synthesis on the surface of S. cerevisiae cells, with bioATRP outperforming bioRAFT polym…
View article: Small extracellular vesicle‐derived miR‐574‐5p regulates PGE2‐biosynthesis via TLR7/8 in lung cancer
Small extracellular vesicle‐derived miR‐574‐5p regulates PGE2‐biosynthesis via TLR7/8 in lung cancer Open
Intercellular communication plays an essential role in lung cancer (LC). One of the major players in cell‐cell‐communication is small extracellular vesicles (sEV). SEV trigger various biological responses by transporting cellular cargo to …
View article: A Functional K+ Channel from Tetraselmis Virus 1, a Member of the Mimiviridae
A Functional K+ Channel from Tetraselmis Virus 1, a Member of the Mimiviridae Open
Potassium ion (K+) channels have been observed in diverse viruses that infect eukaryotic marine and freshwater algae. However, experimental evidence for functional K+ channels among these alga-infecting viruses has thus far been restricted…
View article: Co-curing of epoxy resins with aminated lignins: insights into the role of lignin homo crosslinking during lignin amination on the elastic properties
Co-curing of epoxy resins with aminated lignins: insights into the role of lignin homo crosslinking during lignin amination on the elastic properties Open
To improve the reactivity of lignin for incorporation into high value polymers, the introduction of amines via Mannich reaction is a commonly used strategy. During this functionalization reaction, intra- as well as intermolecular lignin–li…
View article: Genetic Diversity of Potassium Ion Channel Proteins Encoded by Chloroviruses That Infect Chlorella heliozoae
Genetic Diversity of Potassium Ion Channel Proteins Encoded by Chloroviruses That Infect Chlorella heliozoae Open
Chloroviruses are large, plaque-forming, dsDNA viruses that infect chlorella-like green algae that live in a symbiotic relationship with protists. Chloroviruses have genomes from 290 to 370 kb, and they encode as many as 400 proteins. One …
View article: The mutation L69P in the PAS domain of the hERG potassium channel results in LQTS by trafficking deficiency
The mutation L69P in the PAS domain of the hERG potassium channel results in LQTS by trafficking deficiency Open
The congenital long QT syndrome (LQTS) is a cardiac disorder characterized by a prolonged QT interval on the electrocardiogram and an increased susceptibility to ventricular arrhythmias and sudden cardiac death. A frequent cause for LQTS i…
View article: The mutation L69P in the PAS domain of the hERG potassium channel results in LQTS by trafficking deficiency
The mutation L69P in the PAS domain of the hERG potassium channel results in LQTS by trafficking deficiency Open
The congenital long QT syndrome (LQTS) is a cardiac disorder characterized by a prolonged QT interval on the electrocardiogram and an increased susceptibility to ventricular arrhythmias and sudden cardiac death. A frequent cause for LQTS i…
View article: A small viral potassium ion channel with an inherent inward rectification
A small viral potassium ion channel with an inherent inward rectification Open
Some algal viruses have coding sequences for K + channels with structural and functional characteristics of pore modules of complex K + channels. Here we exploit the immense structural diversity of natural channel orthologs to discover new…
View article: A small viral potassium ion channel with an inherent inward rectification
A small viral potassium ion channel with an inherent inward rectification Open
Some algal viruses have coding sequences for proteins with structural and functional characteristics of pore modules of complex K+ channels. Here we exploit the structural diversity among these channel orthologs to discover new basic princ…
View article: Conversion of an instantaneous activating K<sup>+</sup> channel into a slow activating inward rectifier
Conversion of an instantaneous activating K<sup>+</sup> channel into a slow activating inward rectifier Open
The miniature channel, Kcv, is a structural equivalent of the pore of all K + channels. Here, we follow up on a previous observation that a largely voltage‐insensitive channel can be converted into a slow activating inward rectifier after …
View article: Ion Channel Activity of Vpu Proteins Is Conserved throughout Evolution of HIV-1 and SIV
Ion Channel Activity of Vpu Proteins Is Conserved throughout Evolution of HIV-1 and SIV Open
The human immunodeficiency virus type 1 (HIV-1) protein Vpu is encoded exclusively by HIV-1 and related simian immunodeficiency viruses (SIVs). The transmembrane domain of the protein has dual functions: it counteracts the human restrictio…
View article: High‐Resolution Membrane Capacitance Measurements for Studying Endocytosis and Exocytosis in Yeast
High‐Resolution Membrane Capacitance Measurements for Studying Endocytosis and Exocytosis in Yeast Open
With patch‐clamp recording, we detect in yeast protoplasts individual exo‐ and endocytotic events as discrete steps in membrane capacitance. The high‐resolution data show that exo‐ and endocytotic vesicles undergo, similar to other eukaryo…