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View article: Protective Role of Gallic Acid Against Corticosterone-Induced Hepatic Toxicity: Modulation of Oxidative Stress and Inflammatory Pathways in Wistar Rats
Protective Role of Gallic Acid Against Corticosterone-Induced Hepatic Toxicity: Modulation of Oxidative Stress and Inflammatory Pathways in Wistar Rats Open
Corticosterone (CORT), a key stress hormone, is vital for energy balance, but prolonged exposure causes hyperglycemia, obesity, and hepatotoxicity. Gallic acid (GA), a natural polyphenol with antioxidant and anti-inflammatory properties, w…
View article: Dopamine D2 receptor gene Taq 1A polymorphism: genetic architecture in Indian population and comparison to global populations
Dopamine D2 receptor gene Taq 1A polymorphism: genetic architecture in Indian population and comparison to global populations Open
Objective The Dopamine receptor D2 (DRD2) gene has been investigated as a candidate gene in several psychiatric and neurological disorders involving dopaminergic systems. Multiple polymorphisms have been reported in the DRD2 gene, where th…
View article: Targeting Oxidative Stress Biomarkers in Breast Cancer Development and the Potential Protective Effect of Phytochemicals
Targeting Oxidative Stress Biomarkers in Breast Cancer Development and the Potential Protective Effect of Phytochemicals Open
Breast cancer continues to represent one of the most widespread and lethal health afflictions on a global scale. The advancement of this malignancy is predominantly influenced by genetic mutations that precipitate unregulated cellular grow…
View article: Molecular Mechanisms of Phthalate-Induced Hepatic Injury and Amelioration by Plant-Based Principles
Molecular Mechanisms of Phthalate-Induced Hepatic Injury and Amelioration by Plant-Based Principles Open
Phthalates are the emerging environmental toxicants derived from phthalic acid and its constituents, which are moderately present in plastics and many personal care products. Phthalate exposure occurs through various environmental factors,…
View article: Phytochemical profiling, antioxidant potential and cytotoxic activity of <i>Sargassum prismaticum</i> extracts: implications for therapeutic applications
Phytochemical profiling, antioxidant potential and cytotoxic activity of <i>Sargassum prismaticum</i> extracts: implications for therapeutic applications Open
Seaweeds are sources of bioactive compounds with medicinal properties, which make them attractive candidates for natural therapeutic agents. Marine brown algae are known to possess anti-inflammatory, hepatoprotective, anticancer properties…
View article: Cardioprotective effect of eugenol against Cd-induced inflammation, oxidative stress and dyslipidemia in male rats: An invivo and molecular docking study
Cardioprotective effect of eugenol against Cd-induced inflammation, oxidative stress and dyslipidemia in male rats: An invivo and molecular docking study Open
Background Cadmium, a highly toxic heavy metal, can cause severe damage to several vital organs including the kidney, liver and brain. Many of the natural compounds found in aromatic plants have beneficial pharmacological properties, Eugen…
View article: REVOLUTIONIZING WASTE COOKING OIL: ENHANCING QUALITY AND PHYSICOCHEMICAL PROPERTIES THROUGH SILICA EMBEDDED CHITOSAN MEMBRANE
REVOLUTIONIZING WASTE COOKING OIL: ENHANCING QUALITY AND PHYSICOCHEMICAL PROPERTIES THROUGH SILICA EMBEDDED CHITOSAN MEMBRANE Open
Prior research indicates that chitosan membranes exhibit a highly rigid and non-porous morphology, limiting their utility in filtration applications. To enhance the performance characteristics of chitosan membranes, modification strategies…
View article: A Review on Toxins Mediated Neuro Diseases and Ameliorative Role of Certain Phytochemicals
A Review on Toxins Mediated Neuro Diseases and Ameliorative Role of Certain Phytochemicals Open
According to an estimate, about 6.8 million people die every year as a result of neurological disorders. These disorders arise due to degeneration of nerve cells and disrupt normal brain functions impacting personal and professional behavi…
View article: Cancer-Preventive Activity of Argemone mexicana Linn Leaves and Its Effect on TNF-α and NF-κB Signalling
Cancer-Preventive Activity of Argemone mexicana Linn Leaves and Its Effect on TNF-α and NF-κB Signalling Open
Skin cancer is the 5th most common cancer in Western countries with a surge in case occurrences making it a global burden on healthcare systems. The present study aims to evaluate the cancer-preventive activity of an ethanolic extract of A…
View article: Cancer-Preventive Activity of Argemone mexicana Linn Leaves and Interpretation of Its Orchestral Effect on TNF-α and NF-kB Signaling Modulation in DMBA/TPA Induced Skin Cancer Mice Model
Cancer-Preventive Activity of Argemone mexicana Linn Leaves and Interpretation of Its Orchestral Effect on TNF-α and NF-kB Signaling Modulation in DMBA/TPA Induced Skin Cancer Mice Model Open
Introduction: Skin cancer is the 5th most common cancers in western countries with surge in the cases of occurrence with the passing time making it a global burden on health care system. In this present study, the cancer preventive activit…
View article: Antioxidative effect of Aloe vera against malathion induced neurotoxic response in Wistar rats
Antioxidative effect of Aloe vera against malathion induced neurotoxic response in Wistar rats Open
Insight about the impact of malathion on human physiology is still a challenge in environmental health. The present work was focused on the neurotoxic effects of malathion followed by impact of Aloe vera, if any, which is not known. The ma…
View article: A study on Transaminases in Lindane Exposed Fish C. punctatus
A study on Transaminases in Lindane Exposed Fish C. punctatus Open
The transaminases such as Glutamate Oxaloacetate Transaminase (GOT or AST) and Glutamate Pyruvate Transaminase (GPT or ALT) are the key enzymes known for their roles in utilization of protein and carbohydrates. The activities of these two …
View article: Analysis of Biochemical and Antimicrobial Properties of Bioactive Molecules of Argemone mexicana
Analysis of Biochemical and Antimicrobial Properties of Bioactive Molecules of Argemone mexicana Open
This study identified phytochemicals in Argemone mexicana (A. mexicana) extracts that are responsible for its medicinal properties, and the best solvent for their extraction. The extracts of the stem, leaves, flowers, and fruits of A. mexi…
View article: Elucidation of the Anticancer Mechanism of Durian Fruit (Durio zibethinus) Pulp Extract in Human Leukemia (HL-60) Cancer Cells
Elucidation of the Anticancer Mechanism of Durian Fruit (Durio zibethinus) Pulp Extract in Human Leukemia (HL-60) Cancer Cells Open
Durian (Durio zibethinus L.) grows widely in Southeast Asia. The pulp of the durian fruit contains carbohydrates, proteins, lipids, fibers, various vitamins, minerals, and fatty acids. This study was carried out to elucidate the anticancer…
View article: Amelioration of Hepatotoxic and Neurotoxic Effect of Cartap by Aloe vera in Wistar Rats
Amelioration of Hepatotoxic and Neurotoxic Effect of Cartap by Aloe vera in Wistar Rats Open
Pesticide exposure can pose a serious risk to nontarget animals. Cartap is being broadly used in agricultural fields. The toxic effects of cartap on the levels of hepatotoxicity and neurotoxicity have not been properly studied in mammalian…
View article: Long Term Treatment of Corticostreroids May Cause Hepatotoxicity and Oxidative Damage: A Case Controlled Study
Long Term Treatment of Corticostreroids May Cause Hepatotoxicity and Oxidative Damage: A Case Controlled Study Open
View article: Recent Advances in Biogenic Silver Nanoparticles for Their Biomedical Applications
Recent Advances in Biogenic Silver Nanoparticles for Their Biomedical Applications Open
Owing to the unique property of large surface area/volume of nanoparticles, scientific developments have revolutionized the fields of nanotechnology. Nanoparticles can be synthesized through physical, chemical, and biological routes, where…
View article: Evaluation of Levels of Phosphatases in the Lindane Exposed Fish, Channa punctatus
Evaluation of Levels of Phosphatases in the Lindane Exposed Fish, Channa punctatus Open
The alterations in the activities of acid and alkaline phosphatase are good indicators of stress due to the exposure of fish to any toxicant. The perturbations in their activities may result in the decreased immune responses and intestinal…
View article: Root Exudates: Mechanistic Insight of Plant Growth Promoting Rhizobacteria for Sustainable Crop Production
Root Exudates: Mechanistic Insight of Plant Growth Promoting Rhizobacteria for Sustainable Crop Production Open
The breaking silence between the plant roots and microorganisms in the rhizosphere affects plant growth and physiology by impacting biochemical, molecular, nutritional, and edaphic factors. The components of the root exudates are associate…
View article: Hepatoprotective Effect of Ethanolic Extract of Garlic Against Reserpine Induced Toxicity in Wistar Rats
Hepatoprotective Effect of Ethanolic Extract of Garlic Against Reserpine Induced Toxicity in Wistar Rats Open
View article: Phytochemical Profiling of Microalgae Euglena tuba and Its Anticancer Activity in Dalton's Lymphoma Cells
Phytochemical Profiling of Microalgae Euglena tuba and Its Anticancer Activity in Dalton's Lymphoma Cells Open
Introduction: Natural phytochemicals are considered safe to use as therapeutic agents. There is a growing trend toward exploring anticancer effects of crude algal extracts or their active ingredients. Euglena tuba, a microalga, contains ex…
View article: In-Utero Neurotoxicity of Nanoparticles
In-Utero Neurotoxicity of Nanoparticles Open
The unique physicochemical properties of nanoparticles (NPs) make them widely used in cosmetics, medicines, food additives, and antibacterial and antiviral compounds. NPs are also used in therapy and diagnostic applications. Depending on t…
View article: Biochemical Characterization of Different Chemical Components of <i>Parthenium hysterophorus</i> and Their Therapeutic Potential against HIV‐1 RT and Microbial Growth
Biochemical Characterization of Different Chemical Components of <i>Parthenium hysterophorus</i> and Their Therapeutic Potential against HIV‐1 RT and Microbial Growth Open
Parthenium hysterophorus possesses certain allelochemicals responsible for their medicinal effects. The presence of oils, polyphenols, alkaloids, terpenes, pseudoguaianolides, and histamines in P. hysterophorus has been shown to exhibit me…
View article: Biogenic Synthesis and Characterization of Antioxidant and Antimicrobial Silver Nanoparticles Using Flower Extract of Couroupita guianensis Aubl.
Biogenic Synthesis and Characterization of Antioxidant and Antimicrobial Silver Nanoparticles Using Flower Extract of Couroupita guianensis Aubl. Open
Couroupita guianensis Aubl. is an important medicinal tree. This tree is rich in various phytochemicals, and is therefore used as a potent antioxidant and antibacterial agent. This plant is also used for the treatment of various diseases. …
View article: Protective Effect of Methanolic Extract of Euglena tuba Against Dalton Lymphoma Induced Oxidative Stress in BALB/c Mice
Protective Effect of Methanolic Extract of Euglena tuba Against Dalton Lymphoma Induced Oxidative Stress in BALB/c Mice Open
View article: Repurposing of gastric cancer drugs against COVID-19
Repurposing of gastric cancer drugs against COVID-19 Open
View article: Meet Our Editorial Board Member
Meet Our Editorial Board Member Open
View article: Environmental and Health Hazards of Chromated Copper Arsenate-Treated Wood: A Review
Environmental and Health Hazards of Chromated Copper Arsenate-Treated Wood: A Review Open
Copper chrome arsenate (CCA) water-borne solution used to be widely used to make timber highly resistant to pests and fungi, in particular, wood products designed for outdoor use. Nowadays, CCA is a restricted chemical product in most coun…
View article: Conifers Phytochemicals: A Valuable Forest with Therapeutic Potential
Conifers Phytochemicals: A Valuable Forest with Therapeutic Potential Open
Conifers have long been recognized for their therapeutic potential in different disorders. Alkaloids, terpenes and polyphenols are the most abundant naturally occurring phytochemicals in these plants. Here, we provide an overview of the ph…
View article: Protective effect of eugenol on hepatic inflammation and oxidative stress induced by cadmium in male rats
Protective effect of eugenol on hepatic inflammation and oxidative stress induced by cadmium in male rats Open