Brittney O. Baumert
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View article: Associations between per- and polyfluoroalkyl substances and metabolic dysfunction-associated steatotic liver disease in adolescents and young adults: modifying roles of age, lifestyle factors, and PNPLA3 genotype
Associations between per- and polyfluoroalkyl substances and metabolic dysfunction-associated steatotic liver disease in adolescents and young adults: modifying roles of age, lifestyle factors, and PNPLA3 genotype Open
Studies in youth on per- and polyfluoroalkyl substances (PFAS) exposure and metabolic dysfunction-associated steatotic liver disease (MASLD) are limited. The study aimed to evaluate associations between PFAS and MASLD risk and the modifyin…
View article: Translational framework linking perfluoroheptanoic acid (PFHpA) exposure to metabolic dysfunction associated steatotic liver disease in adolescents
Translational framework linking perfluoroheptanoic acid (PFHpA) exposure to metabolic dysfunction associated steatotic liver disease in adolescents Open
This study offers evidence implicating PFHpA, a short-chain unregulated PFAS congener, in MASLD development in adolescents, and highlights the critical role of protein dysregulation in disease pathogenesis. The molecular mechanisms identif…
View article: <scp>PFAS</scp> Exposure and Postoperative Weight Regain in Adolescents After Bariatric Surgery: Findings From the Teen‐<scp>LABS</scp> Study
<span>PFAS</span> Exposure and Postoperative Weight Regain in Adolescents After Bariatric Surgery: Findings From the Teen‐<span>LABS</span> Study Open
Objective Weight regain following bariatric surgery remains a clinical challenge, with limited understanding of contributing environmental factors. Per‐ and polyfluoroalkyl substances (PFAS), persistent chemicals linked to metabolic dysfun…
View article: Chrome Plating Facility Siting Is Associated with Neighborhood Demographic and Socioeconomic Factors and Elevated Per- and Polyfluoroalkyl Substances in Blood in California
Chrome Plating Facility Siting Is Associated with Neighborhood Demographic and Socioeconomic Factors and Elevated Per- and Polyfluoroalkyl Substances in Blood in California Open
Chrome plating facilities release toxic chemicals, including perfluoroalkyl and polyfluoroalkyl substances (PFAS), disproportionately affecting nearby neighborhoods. We analyzed census-tract-level demographic and socioeconomic data using t…
View article: Beyond the Surface: Mapping DDE’s Metabolic Footprint on Adolescent Obesity
Beyond the Surface: Mapping DDE’s Metabolic Footprint on Adolescent Obesity Open
These findings enhance our understanding of DDE's obesogenic effect. The involved metabolic changes could attenuate the efficacy of bariatric surgery in achieving sustained weight loss, underscoring the importance of integrating environmen…
View article: Corrigendum to “Associations of dietary intake and longitudinal measures of per- and polyfluoroalkyl substances (PFAS) in predominantly Hispanic young Adults: a multicohort study” [Environ. Int 185 (2024) 108454]
Corrigendum to “Associations of dietary intake and longitudinal measures of per- and polyfluoroalkyl substances (PFAS) in predominantly Hispanic young Adults: a multicohort study” [Environ. Int 185 (2024) 108454] Open
View article: Integrated Spheroid-to-Population Framework for Evaluating PFHpA-Associated Metabolic Dysfunction and Steatotic Liver Disease
Integrated Spheroid-to-Population Framework for Evaluating PFHpA-Associated Metabolic Dysfunction and Steatotic Liver Disease Open
View article: Metabolic Signatures in Adipose Tissue Linking Lipophilic Persistent Organic Pollutant Mixtures to Blood Pressure Five Years After Bariatric Surgery Among Adolescents
Metabolic Signatures in Adipose Tissue Linking Lipophilic Persistent Organic Pollutant Mixtures to Blood Pressure Five Years After Bariatric Surgery Among Adolescents Open
Persistent organic pollutants (POPs) are lipophilic environmental contaminants accumulated in the adipose tissue. Weight loss interventions, such as bariatric surgery, can mobilize POPs from adipose tissue into the bloodstream. We hypothes…
View article: Per-and polyfluoroalkyl substances and disrupted sleep: mediating roles of proteins
Per-and polyfluoroalkyl substances and disrupted sleep: mediating roles of proteins Open
View article: Applications of mixture methods in epidemiological studies investigating the health impact of persistent organic pollutants exposures: a scoping review
Applications of mixture methods in epidemiological studies investigating the health impact of persistent organic pollutants exposures: a scoping review Open
Background Persistent organic pollutants (POPs) are environmental chemicals characterized by long half-lives in nature and human bodies, posing significant health risks. The concept of the exposome, encompassing all lifetime environmental …
View article: Exposure to Perfluoroalkyl Substances is Associated with Longitudinal Changes in Adiposity in a Hispanic Adolescent Cohort
Exposure to Perfluoroalkyl Substances is Associated with Longitudinal Changes in Adiposity in a Hispanic Adolescent Cohort Open
View article: PFAS are associated with perturbations of lipid metabolism in adolescents
PFAS are associated with perturbations of lipid metabolism in adolescents Open
View article: Associations Between PFAS and Longitudinal Changes in Insulin Sensitivity in Adolescents
Associations Between PFAS and Longitudinal Changes in Insulin Sensitivity in Adolescents Open
View article: Coupling observational study with computational toxicology to elucidate the relationships and potential mechanisms of per-and polyfluoroalkyl substances and sleep
Coupling observational study with computational toxicology to elucidate the relationships and potential mechanisms of per-and polyfluoroalkyl substances and sleep Open
View article: A Per- and Polyfluoroalkyl Substance Mixture Associated with Human Gut Microbiota: Novel Bayesian Hierarchical Zero-Inflated Negative Binomial Regression with G-Computation
A Per- and Polyfluoroalkyl Substance Mixture Associated with Human Gut Microbiota: Novel Bayesian Hierarchical Zero-Inflated Negative Binomial Regression with G-Computation Open
View article: Association between per- and polyfluoroalkyl substances (PFAS) exposure and kidney function in young adults
Association between per- and polyfluoroalkyl substances (PFAS) exposure and kidney function in young adults Open
View article: Lipophilic Persistent Organic Pollutant and Percentage Changes of Blood Pressure Five Years after Bariatric Surgery among Adolescents: A Mixtures Approach
Lipophilic Persistent Organic Pollutant and Percentage Changes of Blood Pressure Five Years after Bariatric Surgery among Adolescents: A Mixtures Approach Open
View article: PFHpA alters lipid metabolism and increases the risk of metabolic dysfunction-associated steatotic liver disease (MASLD) in youth—a translational research framework
PFHpA alters lipid metabolism and increases the risk of metabolic dysfunction-associated steatotic liver disease (MASLD) in youth—a translational research framework Open
View article: Identifying metabolic mediators between concentration of {p,p’}-DDE in visceral adipose tissue and weight loss in adolescents undergoing bariatric surgery
Identifying metabolic mediators between concentration of {p,p’}-DDE in visceral adipose tissue and weight loss in adolescents undergoing bariatric surgery Open
View article: PFHpA alters lipid metabolism and increases the risk of metabolic dysfunction-associated steatotic liver disease in youth—a translational research framework
PFHpA alters lipid metabolism and increases the risk of metabolic dysfunction-associated steatotic liver disease in youth—a translational research framework Open
To address the growing epidemic of liver disease, particularly in pediatric populations, it is crucial to identify modifiable risk factors for the development and progression of metabolic dysfunction-associated steatotic liver disease (MAS…
View article: Exposure to per- and polyfluoroalkyl substances and alterations in plasma microRNA profiles in children
Exposure to per- and polyfluoroalkyl substances and alterations in plasma microRNA profiles in children Open
View article: Changes in plasma concentrations of per- and Polyfluoroalkyl substances after bariatric surgery in adolescents from the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study
Changes in plasma concentrations of per- and Polyfluoroalkyl substances after bariatric surgery in adolescents from the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) study Open
View article: Exposure to per- and polyfluoroalkyl substances and high-throughput proteomics in Hispanic youth
Exposure to per- and polyfluoroalkyl substances and high-throughput proteomics in Hispanic youth Open
PFAS was associated with broad alterations of the proteomic profiles linked to pro-inflammation and immunoregulation. The biological functions of these proteins provide insight into potential molecular mechanisms of PFAS toxicity.
View article: Exposure to 4,4′‐<scp>DDE</scp> in visceral adipose tissue and weight loss in adolescents from the <scp>Teen‐LABS</scp> cohort
Exposure to 4,4′‐<span>DDE</span> in visceral adipose tissue and weight loss in adolescents from the <span>Teen‐LABS</span> cohort Open
Objective Dichlorodiphenyldichloroethylene (DDE), an obesogen accumulating in adipose tissue, is released into circulation with weight loss, although its impact is underexplored among adolescents. We tested the association using an integra…
View article: Associations of dietary intake and longitudinal measures of per- and polyfluoroalkyl substances (PFAS) in predominantly Hispanic young Adults: A multicohort study
Associations of dietary intake and longitudinal measures of per- and polyfluoroalkyl substances (PFAS) in predominantly Hispanic young Adults: A multicohort study Open
View article: Proteomic and Metabolomic Signatures of Diet Quality in Young Adults
Proteomic and Metabolomic Signatures of Diet Quality in Young Adults Open
The assessment of “omics” signatures may contribute to personalized medicine and precision nutrition. However, the existing literature is still limited in the homogeneity of participants’ characteristics and in limited assessments of integ…
View article: Circulating microRNA expression and nonalcoholic fatty liver disease in adolescents with severe obesity
Circulating microRNA expression and nonalcoholic fatty liver disease in adolescents with severe obesity Open
BACKGROUND Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases in children and adolescents. NAFLD ranges in severity from isolated hepatic steatosis to nonalcoholic steatohepatitis (NASH), wherein hepa…
View article: Exposure to Per- and Polyfluoroalkyl Substances and Alterations in Plasma Microrna Profiles in Children
Exposure to Per- and Polyfluoroalkyl Substances and Alterations in Plasma Microrna Profiles in Children Open
View article: A long and winding road: culture change on data sharing in exposomics
A long and winding road: culture change on data sharing in exposomics Open
Data sharing requires cooperation from data generators (eg, epidemiologists, lab investigators) and data users (eg, epidemiologists, biostatisticians, computer scientists). Data generation and data use in human exposome studies require sig…
View article: Changes in Plasma Concentrations of Per- and Polyfluoroalkyl Substances after Bariatric Surgery in Adolescents from the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-Labs) Study
Changes in Plasma Concentrations of Per- and Polyfluoroalkyl Substances after Bariatric Surgery in Adolescents from the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-Labs) Study Open