Bronwen Connolly
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View article: Waiting is the hardest part: patient, caregiver and clinician perspectives on shaping prehabilitation support strategies in liver transplantation
Waiting is the hardest part: patient, caregiver and clinician perspectives on shaping prehabilitation support strategies in liver transplantation Open
Objective Exploring the unmet needs of patients awaiting liver transplantation remains largely unexplored and with no established multicomponent support mechanisms currently available, identifying these needs could provide better, tailored…
View article: Development of a patient centred, structured, individually tailored, multi-component intervention to promote rehabilitation and recovery after critical illness: content, theory, and construction.
Development of a patient centred, structured, individually tailored, multi-component intervention to promote rehabilitation and recovery after critical illness: content, theory, and construction. Open
Background/aims This paper describes the development (content, theory, and construction) of a patient-centered, structured, individually tailored, multicomponent intervention (the iRehab intervention) to promote rehabilitation and recovery…
View article: Insights from clinicians on reconnecting with survivors of critical illness: An international qualitative investigation
Insights from clinicians on reconnecting with survivors of critical illness: An international qualitative investigation Open
This research has explored the experience of reconnection between critical care survivors and clinicians from a clinician perspective. It has shown potential benefits for clinician wellbeing as well as the delivery of care within the criti…
View article: Remote multicomponent rehabilitation compared to standard care for survivors of critical illness after hospital discharge (iRehab): a protocol for a randomised controlled assessor-blind clinical and cost-effectiveness trial
Remote multicomponent rehabilitation compared to standard care for survivors of critical illness after hospital discharge (iRehab): a protocol for a randomised controlled assessor-blind clinical and cost-effectiveness trial Open
Background The consequences of critical illness can be substantial and multifactorial, encompassing physical deconditioning, mental health impairments, fatigue, and declines in health-related quality of life. We hypothesise that for peopl…
View article: What measures have been used to explore the outcomes of family members of critically ill patients: a scoping review
What measures have been used to explore the outcomes of family members of critically ill patients: a scoping review Open
View article: Development of a patient centred, structured, individually tailored, multi-component intervention to promote rehabilitation and recovery after critical illness: content, theory, and construction.
Development of a patient centred, structured, individually tailored, multi-component intervention to promote rehabilitation and recovery after critical illness: content, theory, and construction. Open
Background/aims This paper describes the development (content, theory, and construction) of a patient-centered, structured, individually tailored, multicomponent intervention (the iRehab intervention) to promote rehabilitation and recovery…
View article: Provision of follow-up services for survivors of COVID-19 critical illness: A UK national survey
Provision of follow-up services for survivors of COVID-19 critical illness: A UK national survey Open
Background: Intensive care unit (ICU) survivors in the United Kingdom (UK) can receive support from ICU follow-up services in their process of recovery and rehabilitation. However, it is unclear whether the COVID-19 pandemic impacted the a…
View article: Top 10 research priorities for sepsis research determined by patients, carers and clinicians
Top 10 research priorities for sepsis research determined by patients, carers and clinicians Open
Summary Introduction Sepsis is a high burden syndrome associated with increased morbidity and mortality in both the acute and longer‐term phases of illness. Multiple treatment uncertainties remain that require resolution through high‐quali…
View article: Device-based measurement of physical activity and sedentary behaviour after critical illness: A scoping review
Device-based measurement of physical activity and sedentary behaviour after critical illness: A scoping review Open
Introduction Measuring and promoting physical activity could support rehabilitation and recovery after critical illness. In recent years, there has been an emergence of the use of devices to measure both physical activity and sedentary beh…
View article: Implementation of a Quality Improvement Tool “Recover25” to Guide the Care of Patients Experiencing Prolonged Critical Illness: A Mixed-Method Feasibility Study
Implementation of a Quality Improvement Tool “Recover25” to Guide the Care of Patients Experiencing Prolonged Critical Illness: A Mixed-Method Feasibility Study Open
OBJECTIVES: Few quality improvement (QI) tools are specifically designed to manage the care of patients experiencing prolonged critical illness. This risks omissions in care. To determine the implementation feasibility and clinician accept…
View article: Development of a clinical core outcome set to evaluate lung cancer rehabilitation
Development of a clinical core outcome set to evaluate lung cancer rehabilitation Open
Introduction Significant heterogeneity exists in the outcomes and instruments used in clinical practice to evaluate lung cancer rehabilitation. This study aimed to develop a lung cancer rehabilitation clinical core outcome set and establis…
View article: Remote multicomponent rehabilitation compared to standard care for survivors of critical illness after hospital discharge (iRehab): a protocol for a randomised controlled assessor-blind clinical and cost-effectiveness trial
Remote multicomponent rehabilitation compared to standard care for survivors of critical illness after hospital discharge (iRehab): a protocol for a randomised controlled assessor-blind clinical and cost-effectiveness trial Open
Background The consequences of critical illness can be substantial and multifactorial, encompassing physical deconditioning, mental health impairments, fatigue, and declines in health-related quality of life. We hypothesise that for peopl…
View article: Effectiveness of mucoactives (carbocisteine and hypertonic saline) in addition to usual airway clearance management with usual airway clearance management alone in acute respiratory failure (MARCH): study protocol for a multi-centre 2x2 factorial, randomised, controlled, open-label, Phase 3, pragmatic, clinical and cost-effectiveness trial with internal pilot
Effectiveness of mucoactives (carbocisteine and hypertonic saline) in addition to usual airway clearance management with usual airway clearance management alone in acute respiratory failure (MARCH): study protocol for a multi-centre 2x2 factorial, randomised, controlled, open-label, Phase 3, pragmatic, clinical and cost-effectiveness trial with internal pilot Open
Background Usual airway clearance management in critically ill patients with acute respiratory failure includes suctioning, humidification, use of isotonic saline, and respiratory physiotherapy techniques. Escalation to use of mucoactives…
View article: THE CORE OF HARVEY WEINSTEIN'S BIG APPLE REVERSAL: A CLOSER LOOK AT THE CONTROVERSIAL YET CORRECT APPLICATION OF MOLINEUX AND SANDOVAL BY THE NEW YORK COURT OF APPEALS
THE CORE OF HARVEY WEINSTEIN'S BIG APPLE REVERSAL: A CLOSER LOOK AT THE CONTROVERSIAL YET CORRECT APPLICATION OF MOLINEUX AND SANDOVAL BY THE NEW YORK COURT OF APPEALS Open
View article: Reporting of nutritional screening, status, and intake in trials of nutritional and physical rehabilitation following critical illness: a systematic review
Reporting of nutritional screening, status, and intake in trials of nutritional and physical rehabilitation following critical illness: a systematic review Open
View article: Animal-assisted intervention services across UK intensive care units: A national service evaluation
Animal-assisted intervention services across UK intensive care units: A national service evaluation Open
Background: Animal-assisted interventions (AAI) can provide psychological support to critical care patients during their intensive care unit (ICU) admission. However, there are currently no data on AAI services across UK ICUs. The current …
View article: SLPI deficiency alters airway protease activity and induces cell recruitment in a model of muco-obstructive lung disease
SLPI deficiency alters airway protease activity and induces cell recruitment in a model of muco-obstructive lung disease Open
Secretory leukocyte protease inhibitor (SLPI) is an important cationic protein involved in innate airway immunity and highly expressed in mucosal secretions, shown to target and inhibit neutrophil elastase (NE), cathepsin G and trypsin act…
View article: Codesign of a Quality Improvement Tool for Adults With Prolonged Critical Illness: A Modified Delphi Consensus Study
Codesign of a Quality Improvement Tool for Adults With Prolonged Critical Illness: A Modified Delphi Consensus Study Open
OBJECTIVES: Increasing numbers of patients experience a prolonged stay in intensive care. Yet existing quality improvement (QI) tools used to improve safety and standardize care are not designed for their specific needs. This may result in…
View article: PRACTICE: Development of a Core Outcome Set for Trials of Physical Rehabilitation in Critical Illness
PRACTICE: Development of a Core Outcome Set for Trials of Physical Rehabilitation in Critical Illness Open
Rationale: Findings from individual trials of physical rehabilitation interventions in critically ill adults have limited potential for meta-analysis and informing clinical decision-making because of the heterogeneity in selection a…
View article: Using patient and care partner experiences to confirm outcomes of relevance for inclusion in a core outcome set for trials of physical rehabilitation in critical illness: A qualitative interview study
Using patient and care partner experiences to confirm outcomes of relevance for inclusion in a core outcome set for trials of physical rehabilitation in critical illness: A qualitative interview study Open
COMET Initiative, ID288, https://www.comet-initiative.org/studies/details/288.
View article: Ultrasound-derived rates of muscle wasting in the intensive care unit and in the post-intensive care ward for patients with critical illness: Post hoc analysis of an international, multicentre randomised controlled trial of early rehabilitation
Ultrasound-derived rates of muscle wasting in the intensive care unit and in the post-intensive care ward for patients with critical illness: Post hoc analysis of an international, multicentre randomised controlled trial of early rehabilitation Open
Muscle wasting occurs in critical illness throughout the hospital admission. The average rate of loss in muscle cross-sectional area does not slow after ICU discharge, even with active rehabilitation.
View article: Communication in critical care tracheostomy patients dependent upon cuff inflation: A scoping review
Communication in critical care tracheostomy patients dependent upon cuff inflation: A scoping review Open
Open Science Framework Registries: https://osf.io/kbrjn/.
View article: Tackling Brain and Muscle Dysfunction in Acute Respiratory Distress Syndrome Survivors: NHLBI Workshop Report
Tackling Brain and Muscle Dysfunction in Acute Respiratory Distress Syndrome Survivors: NHLBI Workshop Report Open
Acute respiratory distress syndrome (ARDS) is associated with long-term impairments in brain and muscle function that significantly impact the quality of life of those who survive the acute illness. The mechanisms underlying these impairme…
View article: Clinician views on actionable processes of care for prolonged stay intensive care patients and families: A descriptive qualitative study
Clinician views on actionable processes of care for prolonged stay intensive care patients and families: A descriptive qualitative study Open
These 36 actionable processes of care will contribute to future development of quality improvement tools, which will be used to standardise the care of prolonged-stay intensive care patients and their families.
View article: Rehabilitation outcomes for people with lung cancer (UNITE): protocol for the development of a core outcome set
Rehabilitation outcomes for people with lung cancer (UNITE): protocol for the development of a core outcome set Open
Introduction With treatment-related improvements in survival, rehabilitation is essential to improve function and health-related quality of life and manage the high symptom burden associated with lung cancer. Despite this, significant hete…
View article: Exercise across the Lung Cancer Care Continuum: An Overview of Systematic Reviews
Exercise across the Lung Cancer Care Continuum: An Overview of Systematic Reviews Open
Background: Growing evidence supports exercise for people with lung cancer. This overview aimed to summarise exercise intervention efficacy and safety across the care continuum. Methods: Eight databases (including Cochrane and Medline) wer…
View article: Informing the standardising of care for prolonged stay patients in the intensive care unit: A scoping review of quality improvement tools
Informing the standardising of care for prolonged stay patients in the intensive care unit: A scoping review of quality improvement tools Open
The review protocol is registered on the Open Science Framework, https://osf.io/, DOI 10.17605/OSF.IO/Z8MRE.
View article: Collaborator Name Misspelled
Collaborator Name Misspelled Open
and other sequalae associated with invasive mechanical ventilation, avoidance of tracheal intubation is itself an important outcome to patients, clinicians, and health systems. 3,4 The pragmatic nature of the trial and the context in which…
View article: Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19
Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19 Open
isrctn.org Identifier: ISRCTN16912075.
View article: Addressing the post-acute sequelae of SARS-CoV-2 infection: a multidisciplinary model of care
Addressing the post-acute sequelae of SARS-CoV-2 infection: a multidisciplinary model of care Open