Bruce D. Forrest
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View article: The Effectiveness of NP001 on the Long-Term Survival of Patients with Amyotrophic Lateral Sclerosis
The Effectiveness of NP001 on the Long-Term Survival of Patients with Amyotrophic Lateral Sclerosis Open
Background/Objectives: The aim of this study was to estimate the effect of a 6 months’ treatment course of the innate immune modulator NP001 (a pH-adjusted intravenous formulation of purified sodium chlorite), on disease progression, as me…
View article: The Effectiveness of NP001 on Long Term Survival of Patients with Amyotrophic Lateral Sclerosis: The IKARIA Study
The Effectiveness of NP001 on Long Term Survival of Patients with Amyotrophic Lateral Sclerosis: The IKARIA Study Open
View article: Regulation of the Innate Immune System as a Therapeutic Approach to Supporting Respiratory Function in ALS
Regulation of the Innate Immune System as a Therapeutic Approach to Supporting Respiratory Function in ALS Open
Amyotrophic lateral sclerosis (ALS) is a clinical diagnosis used to define a neurodegenerative process that involves progressive loss of voluntary muscle function and leads to death within 2–5 years after diagnosis, in most cases because o…
View article: Macrophage-Targeted Sodium Chlorite (NP001) Slows Progression of Amyotrophic Lateral Sclerosis (ALS) through Regulation of Microbial Translocation
Macrophage-Targeted Sodium Chlorite (NP001) Slows Progression of Amyotrophic Lateral Sclerosis (ALS) through Regulation of Microbial Translocation Open
Amyotrophic lateral sclerosis (ALS) is a heterogeneous, progressive, and universally fatal neurodegenerative disease. A subset of ALS patients has measurable plasma levels of lipopolysaccharide (LPS) and C-reactive protein (CRP) consistent…