Bruna Pereira Marquezini
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View article: 0059 FOXP1 Gene Regulates the Circadian Clock and Its Loss of Function Impairs Sleep Patterns
0059 FOXP1 Gene Regulates the Circadian Clock and Its Loss of Function Impairs Sleep Patterns Open
Introduction The haploinsufficiency of the FOXP1 protein is associated with a rare genetic disorder of neurodevelopment. Sleep disturbances have already been reported in 45% of patients with pathogenic variants in FOXP1. However, the biolo…
View article: 0056 Pleiotropic Effects of Genetic Variants on Substance Use Disorder and Sleep Patterns
0056 Pleiotropic Effects of Genetic Variants on Substance Use Disorder and Sleep Patterns Open
Introduction Substance use disorder (SUD) is associated with several negative health outcomes, including sleep disorders. Although this correlation is well established, little is known about the genetic mechanisms underlying the comorbidit…