Bruno Millet
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View article: Repetitive Transcranial Magnetic Stimulation targeted with MRI based neuro-navigation in major depressive episode: a double-blind, multicenter randomized controlled trial
Repetitive Transcranial Magnetic Stimulation targeted with MRI based neuro-navigation in major depressive episode: a double-blind, multicenter randomized controlled trial Open
Context High-frequency (HF) transcranial magnetic stimulation (rTMS) of the left dorsolateral prefrontal cortex (DLPFC) is widely used in Major Depressive Episode (MDE). Optimization of its efficacy with a neuro-navigation system has been …
View article: Neurological soft signs as trait markers of a subset of patients with obsessive-compulsive disorder with low insight and altered cognitive abilities
Neurological soft signs as trait markers of a subset of patients with obsessive-compulsive disorder with low insight and altered cognitive abilities Open
View article: Transcranial Magnetic Stimulation (rTMS) on the Precuneus in Alzheimer’s Disease: A Literature Review
Transcranial Magnetic Stimulation (rTMS) on the Precuneus in Alzheimer’s Disease: A Literature Review Open
The current literature review aimed to evaluate the effectiveness of rTMS on the precuneus as a potential treatment for Alzheimer’s disease (AD). Although the number of studies specifically targeting the precuneus is limited, the results f…
View article: Repetitive Transcranial Magnetic Stimulation (rTMS) in Post-Traumatic Stress Disorder: Study Protocol of a Nationwide Randomized Controlled Clinical Trial of Neuro-Enhanced Psychotherapy “TraumaStim”
Repetitive Transcranial Magnetic Stimulation (rTMS) in Post-Traumatic Stress Disorder: Study Protocol of a Nationwide Randomized Controlled Clinical Trial of Neuro-Enhanced Psychotherapy “TraumaStim” Open
The use of high-frequency Transcranial Magnetic Stimulation (HF-rTMS) of the right dorsolateral prefrontal cortex (DLPFC) in treating Post-traumatic Stress Disorder (PTSD) is currently regarded as a level B intervention (probable effective…
View article: Variability in Motor Threshold during Transcranial Magnetic Stimulation Treatment for Depression: Neurophysiological Implications
Variability in Motor Threshold during Transcranial Magnetic Stimulation Treatment for Depression: Neurophysiological Implications Open
The measurement of the motor threshold (MT) is an important element in determining stimulation intensity during Transcranial Magnetic Stimulation treatment (rTMS). The current recommendations propose its realization at least once a week. T…
View article: Digital Phenotyping: Data-Driven Psychiatry to Redefine Mental Health
Digital Phenotyping: Data-Driven Psychiatry to Redefine Mental Health Open
The term “digital phenotype” refers to the digital footprint left by patient-environment interactions. It has potential for both research and clinical applications but challenges our conception of health care by opposing 2 distinct approac…
View article: High treatment resistance is associated with lower performance in the Stroop test in patients with obsessive–compulsive disorder
High treatment resistance is associated with lower performance in the Stroop test in patients with obsessive–compulsive disorder Open
Around 50% of the patients with obsessive–compulsive disorder (OCD) are resistant to treatment, and patients with OCD show alterations in a broad range of cognitive abilities. The present study investigated the links between treatment-resi…
View article: No place in France for repetitive transcranial magnetic stimulation in the therapeutic armamentarium of treatment-resistant depression?
No place in France for repetitive transcranial magnetic stimulation in the therapeutic armamentarium of treatment-resistant depression? Open
International audience
View article: Digital Phenotyping: Data-Driven Psychiatry to Redefine Mental Health (Preprint)
Digital Phenotyping: Data-Driven Psychiatry to Redefine Mental Health (Preprint) Open
UNSTRUCTURED The term “digital phenotype” refers to the digital footprint left by patient-environment interactions. It has potential for both research and clinical applications but challenges our conception of health care by opposing 2 di…
View article: Digital phenotype of mood disorders: A conceptual and critical review
Digital phenotype of mood disorders: A conceptual and critical review Open
Background Mood disorders are commonly diagnosed and staged using clinical features that rely merely on subjective data. The concept of digital phenotyping is based on the idea that collecting real-time markers of human behavior allows us …
View article: Memory reconsolidation impairment using the β-adrenergic receptor blocker propranolol reduces nightmare severity in patients with posttraumatic stress disorder: a preliminary study
Memory reconsolidation impairment using the β-adrenergic receptor blocker propranolol reduces nightmare severity in patients with posttraumatic stress disorder: a preliminary study Open
Mallet C, Chick CF, Maatoug R, Fossati P, Brunet A, Millet B. Memory reconsolidation impairment using the β-adrenergic receptor blocker propranolol reduces nightmare severity in patients with posttraumatic stress disorder: a preliminary st…
View article: Digital Phenotype of Mood Disorders: a conceptual and critical review (Preprint)
Digital Phenotype of Mood Disorders: a conceptual and critical review (Preprint) Open
BACKGROUND Mood disorder is commonly diagnosed and staged using clinical features that rely merely on subjective data. The concept of digital phenotyping is based on the idea that collecting real-time markers of human behavior allow one t…
View article: In Search of Digital Dopamine: How Apps Can Motivate Depressed Patients, a Review and Conceptual Analysis
In Search of Digital Dopamine: How Apps Can Motivate Depressed Patients, a Review and Conceptual Analysis Open
Introduction: Depression is highly prevalent and causes considerable suffering and disease burden despite the existence of wide-ranging treatment options. Momentary assessment is a promising tool in the management of psychiatric disorders,…
View article: Development and Validation of an End-to-End Simulator and Gas Concentration Retrieval Processor Applied to the MERLIN Lidar Mission
Development and Validation of an End-to-End Simulator and Gas Concentration Retrieval Processor Applied to the MERLIN Lidar Mission Open
In the context of MERLIN (MEthane Remote LIdar missioN), a French–German spatial lidar mission dedicated to monitoring the atmospheric methane content, two software programs have been developed: LIDSIM (LIDar SIMulator) and PROLID (PROcess…
View article: Non-invasive and invasive brain stimulation in alcohol use disorders: A critical review of selected human evidence and methodological considerations to guide future research
Non-invasive and invasive brain stimulation in alcohol use disorders: A critical review of selected human evidence and methodological considerations to guide future research Open
View article: Psychothérapie augmentée par rTMS pour les troubles neurologiques fonctionnels
Psychothérapie augmentée par rTMS pour les troubles neurologiques fonctionnels Open
View article: Association of Clinical, Biological, and Brain Magnetic Resonance Imaging Findings With Electroencephalographic Findings for Patients With COVID-19
Association of Clinical, Biological, and Brain Magnetic Resonance Imaging Findings With Electroencephalographic Findings for Patients With COVID-19 Open
The results from this cohort of patients hospitalized with COVID-19 suggest there are clinical, EEG, and MRI patterns that could delineate specific COVID-19-related encephalopathy and guide treatment strategy.
View article: Review for "The negative association between trait mindfulness and post‐traumatic stress disorder: A 4.5‐year prospective cohort study"
Review for "The negative association between trait mindfulness and post‐traumatic stress disorder: A 4.5‐year prospective cohort study" Open
View article: Ecological Momentary Assessment Using Smartphones in Patients With Depression: Feasibility Study
Ecological Momentary Assessment Using Smartphones in Patients With Depression: Feasibility Study Open
Background Ecological momentary assessment (EMA) is a promising tool in the management of psychiatric disorders and particularly depression. It allows for a real-time evaluation of symptoms and an earlier detection of relapse or treatment …
View article: Psychiatric Advance Directives and Artificial Intelligence: A Conceptual Framework for Theoretical and Ethical Principles
Psychiatric Advance Directives and Artificial Intelligence: A Conceptual Framework for Theoretical and Ethical Principles Open
The patient's decision-making abilities are often altered in psychiatric disorders. The legal framework of psychiatric advance directives (PADs) has been made to provide care to patients in these situations while respecting their free and …
View article: The cerebral network of COVID-19-related encephalopathy: a longitudinal voxel-based 18F-FDG-PET study
The cerebral network of COVID-19-related encephalopathy: a longitudinal voxel-based 18F-FDG-PET study Open
View article: The wide spectrum of COVID-19 neuropsychiatric complications within a multidisciplinary centre
The wide spectrum of COVID-19 neuropsychiatric complications within a multidisciplinary centre Open
A variety of neuropsychiatric complications has been described in association with COVID-19 infection. Large scale studies presenting a wider picture of these complications and their relative frequency are lacking. The objective of our stu…
View article: Improving clinical decision-making in psychiatry: implementation of digital phenotyping could mitigate the influence of patient’s and practitioner’s individual cognitive biases
Improving clinical decision-making in psychiatry: implementation of digital phenotyping could mitigate the influence of patient’s and practitioner’s individual cognitive biases Open
High stake clinical choices in psychiatry can be impacted by external irrelevant factors. A strong understanding of the cognitive and behavioural mechanisms involved in clinical reasoning and decision-making is fundamental in improving hea…
View article: Sustained Recovery in a Treatment-Refractory Obsessive–Compulsive Disorder Patient After Deep Brain Stimulation Battery Failure
Sustained Recovery in a Treatment-Refractory Obsessive–Compulsive Disorder Patient After Deep Brain Stimulation Battery Failure Open
Obsessive-compulsive disorder (OCD) is a widespread chronic neuropsychiatric disorder characterized by recurrent intrusive thoughts, images, or urges (obsessions) that typically cause anxiety or distress. Even when optimal treatment is pro…
View article: Soins infirmiers dans la gestion de la COVID-19 au sein du service de psychiatrie adulte de la Pitié-Salpêtrière
Soins infirmiers dans la gestion de la COVID-19 au sein du service de psychiatrie adulte de la Pitié-Salpêtrière Open
View article: The wide spectrum of neuropsychiatric complications in Covid-19 patients within a multidisciplinary hospital context
The wide spectrum of neuropsychiatric complications in Covid-19 patients within a multidisciplinary hospital context Open
Objective To describe the spectrum of neurological and psychiatric complications in patients with Covid-19 seen in a multidisciplinary center over six months. Methods We conducted a retrospective, observational study on all patients showin…
View article: Subthalamic neural oscillations reveal no effect of implicit versus explicit facial emotional processing
Subthalamic neural oscillations reveal no effect of implicit versus explicit facial emotional processing Open
In addition to the subthalamic nucleus’ (STN) role in motor control, STN deep brain stimulation (DBS) for Parkinson’s disease (PD) has also uncovered its involvement in cognitive and limbic processing. STN neural oscillations analyzed thro…
View article: Severe COVID-19-related encephalitis can respond to immunotherapy
Severe COVID-19-related encephalitis can respond to immunotherapy Open
View article: COVID‐19‐related encephalopathy: a case series with brain FDG‐positron‐emission tomography/computed tomography findings
COVID‐19‐related encephalopathy: a case series with brain FDG‐positron‐emission tomography/computed tomography findings Open
Aim The aim of this paper is to describe the clinical features of COVID‐19‐related encephalopathy and their metabolic correlates using brain 2‐desoxy‐2‐fluoro‐D‐glucose (FDG)‐positron‐emission tomography (PET)/computed tomography (CT) imag…
View article: Late-Onset OCD as a Potential Harbinger of Dementia With Lewy Bodies: A Report of Two Cases
Late-Onset OCD as a Potential Harbinger of Dementia With Lewy Bodies: A Report of Two Cases Open
In conclusion, we recommend that cases of late-onset treatment-resistant OCD should be carefully tested for possible organic etiologies, and for DLB in particular.