Bruno Monier
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View article: Cell exit during EMT is mechanically triggered independently of E-Cadherin loss
Cell exit during EMT is mechanically triggered independently of E-Cadherin loss Open
Epithelial-to-mesenchymal transition (EMT) is a fundamental cell process with essential functions in tissue and organ formation during development but also metastasis during cancer progression. The shift between these two states is driven …
View article: Elimination of cells with local mismatch in differentiation timing contributes to synchronize tissue development
Elimination of cells with local mismatch in differentiation timing contributes to synchronize tissue development Open
During animal development, cells communicate to ensure tissue-wide synchronization of differentiation. While several mechanisms contributing to cell coordination have been described, whether additional mechanisms are at play should cells l…
View article: Mechanical state of pre-tumoral epithelia dictates subsequent tumour aggressiveness
Mechanical state of pre-tumoral epithelia dictates subsequent tumour aggressiveness Open
SUMMARY Tumours evolve through the acquisition of increasingly aggressive traits associated with dysplasia. This progression is accompanied by the alteration of tumour mechanical properties, especially through extracellular matrix remodell…
View article: Arp2/3-dependent mechanical control of morphogenetic robustness in an inherently challenging environment
Arp2/3-dependent mechanical control of morphogenetic robustness in an inherently challenging environment Open
View article: Physical and functional cell-matrix uncoupling in a developing tissue under tension
Physical and functional cell-matrix uncoupling in a developing tissue under tension Open
Tissue mechanics play a crucial role in organ development. It relies on cells and extracellular matrix (ECM) mechanical properties, but also on their reciprocal interaction. The relative physical contribution of cells and ECM to morphogene…
View article: Le dernier sursaut des cellules mourantes
Le dernier sursaut des cellules mourantes Open
intégré sur le cancer -programme cancer research for personalized medicine (CARPEM), l'association des gastroentérologues oncologues, le labex immunooncology.
View article: Apico-basal forces exerted by apoptotic cells drive epithelium folding
Apico-basal forces exerted by apoptotic cells drive epithelium folding Open