Bryan J. Mathis
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View article: Three-dimensional image reconstruction technology in laparoscopic pyeloplasty for horseshoe kidney-associated ureteropelvic junction obstruction: a case series study
Three-dimensional image reconstruction technology in laparoscopic pyeloplasty for horseshoe kidney-associated ureteropelvic junction obstruction: a case series study Open
The present study suggests the potential utility of 3D image reconstruction technology in performing LP through detailed preoperative mapping of complex renal anatomies, such as in HSK.
View article: Triple-drug therapy with Goreisan, tranexamic acid and carbazochrome sodium sulfonate hydrate to prevent recurrence after chronic subdural haematoma surgery: a multicentre, randomised, controlled trial protocol
Triple-drug therapy with Goreisan, tranexamic acid and carbazochrome sodium sulfonate hydrate to prevent recurrence after chronic subdural haematoma surgery: a multicentre, randomised, controlled trial protocol Open
Introduction Chronic subdural haematoma (CSDH) is a common neurosurgical condition in older adults, with a recurrence rate of approximately 7.1–13% after burr-hole drainage. Although surgical adjuncts such as subdural drains and middle men…
View article: Endovascular EEG device prospective multicenter single-arm clinical trial to confirm efficacy and safety performance on patients with Intractable Epilepsy: The EPSILON IE trial protocol
Endovascular EEG device prospective multicenter single-arm clinical trial to confirm efficacy and safety performance on patients with Intractable Epilepsy: The EPSILON IE trial protocol Open
Introduction Epilepsy affects approximately 70 million people globally, with around 20−30% of these individuals experiencing drug-resistant epilepsy in which seizures remain uncontrolled despite prolonged treatment with anti-seizure medica…
View article: Safety and pathological impact of resection after high-dose PBT for locally advanced pancreatic cancer.
Safety and pathological impact of resection after high-dose PBT for locally advanced pancreatic cancer. Open
Surgical resection following high-dose PBT can be safely performed under strict selection criteria and demonstrates strong pathological disease control of the primary tumor. This multidisciplinary approach may offer improved outcomes for l…
View article: Data from Prognostic Impact of Immune-Related Adverse Events on Combination Immune Checkpoint/Tyrosine Kinase Inhibition for Metastatic Renal Cancer
Data from Prognostic Impact of Immune-Related Adverse Events on Combination Immune Checkpoint/Tyrosine Kinase Inhibition for Metastatic Renal Cancer Open
Immune checkpoint inhibitor (ICI) combinations and tyrosine kinase inhibitor (TKI) use are standard for metastatic renal cell carcinoma (mRCC), leading to improved outcomes. However, due to a lack of predictive biomarkers, the presence or …
View article: Table 1 from Prognostic Impact of Immune-Related Adverse Events on Combination Immune Checkpoint/Tyrosine Kinase Inhibition for Metastatic Renal Cancer
Table 1 from Prognostic Impact of Immune-Related Adverse Events on Combination Immune Checkpoint/Tyrosine Kinase Inhibition for Metastatic Renal Cancer Open
Patient characteristics.
View article: Table 3 from Prognostic Impact of Immune-Related Adverse Events on Combination Immune Checkpoint/Tyrosine Kinase Inhibition for Metastatic Renal Cancer
Table 3 from Prognostic Impact of Immune-Related Adverse Events on Combination Immune Checkpoint/Tyrosine Kinase Inhibition for Metastatic Renal Cancer Open
Patient characteristics of the ICI–ICI group.
View article: Figure 2 from Prognostic Impact of Immune-Related Adverse Events on Combination Immune Checkpoint/Tyrosine Kinase Inhibition for Metastatic Renal Cancer
Figure 2 from Prognostic Impact of Immune-Related Adverse Events on Combination Immune Checkpoint/Tyrosine Kinase Inhibition for Metastatic Renal Cancer Open
Survival outcomes and multivariable analysis of prognostic factors in the ICI–ICI group. A, Kaplan–Meier curves for OS and PFS. The results of a survival analysis conducted on the ICI–ICI group with and without irAEs. The red line represen…
View article: Supplemental Table 1 from Prognostic Impact of Immune-Related Adverse Events on Combination Immune Checkpoint/Tyrosine Kinase Inhibition for Metastatic Renal Cancer
Supplemental Table 1 from Prognostic Impact of Immune-Related Adverse Events on Combination Immune Checkpoint/Tyrosine Kinase Inhibition for Metastatic Renal Cancer Open
Supplementary Table 1
View article: Table 4 from Prognostic Impact of Immune-Related Adverse Events on Combination Immune Checkpoint/Tyrosine Kinase Inhibition for Metastatic Renal Cancer
Table 4 from Prognostic Impact of Immune-Related Adverse Events on Combination Immune Checkpoint/Tyrosine Kinase Inhibition for Metastatic Renal Cancer Open
Patient characteristics of the ICI–TKI group.
View article: Table 2 from Prognostic Impact of Immune-Related Adverse Events on Combination Immune Checkpoint/Tyrosine Kinase Inhibition for Metastatic Renal Cancer
Table 2 from Prognostic Impact of Immune-Related Adverse Events on Combination Immune Checkpoint/Tyrosine Kinase Inhibition for Metastatic Renal Cancer Open
Status of irAE.
View article: Figure 3 from Prognostic Impact of Immune-Related Adverse Events on Combination Immune Checkpoint/Tyrosine Kinase Inhibition for Metastatic Renal Cancer
Figure 3 from Prognostic Impact of Immune-Related Adverse Events on Combination Immune Checkpoint/Tyrosine Kinase Inhibition for Metastatic Renal Cancer Open
Survival outcomes and multivariable analysis of prognostic factors in the ICI–TKI group. A, Kaplan–Meier curves for OS and PFS. The results of a survival analysis conducted on the ICI–TKI group with and without irAEs. The red line represen…
View article: Figure 1 from Prognostic Impact of Immune-Related Adverse Events on Combination Immune Checkpoint/Tyrosine Kinase Inhibition for Metastatic Renal Cancer
Figure 1 from Prognostic Impact of Immune-Related Adverse Events on Combination Immune Checkpoint/Tyrosine Kinase Inhibition for Metastatic Renal Cancer Open
Kaplan–Meier curves by treatment. The red line represents the ICI–ICI group, and the blue line represents the ICI–TKI group.
View article: Branched-Chain Amino Acids and Testosterone in Older Adults With Type 2 Diabetes: Cross-Sectional and Longitudinal Findings From a Post Hoc Analysis of an Amino Acid Supplementation Trial
Branched-Chain Amino Acids and Testosterone in Older Adults With Type 2 Diabetes: Cross-Sectional and Longitudinal Findings From a Post Hoc Analysis of an Amino Acid Supplementation Trial Open
Cross-sectional associations between serum BCAA and testosterone levels in older adults with T2D were not observed longitudinally and may not reflect direct relationships, but rather influenced by insulin resistance or SHBG levels related …
View article: Verifying the accuracy of Japanese version of the pediatric delirium assessment scale: SOS-PD and the high accuracy of family assessments of pediatric delirium
Verifying the accuracy of Japanese version of the pediatric delirium assessment scale: SOS-PD and the high accuracy of family assessments of pediatric delirium Open
Background Detecting pediatric delirium in critically ill children is important. The Sophia Observation withdrawal Symptoms and Delirium scale (SOS-PD) is a tool for assessing both pediatric delirium and iatrogenic withdrawal symptoms and …
View article: Prognostic Impact of Immune-Related Adverse Events on Combination Immune Checkpoint/Tyrosine Kinase Inhibition for Metastatic Renal Cancer
Prognostic Impact of Immune-Related Adverse Events on Combination Immune Checkpoint/Tyrosine Kinase Inhibition for Metastatic Renal Cancer Open
Immune checkpoint inhibitor (ICI) combinations and tyrosine kinase inhibitor (TKI) use are standard for metastatic renal cell carcinoma (mRCC), leading to improved outcomes. However, due to a lack of predictive biomarkers, the presence or …
View article: Paclitaxel-induced Peripheral Neuropathy and Quality of Life: Sub-analysis of the MICHEL Study
Paclitaxel-induced Peripheral Neuropathy and Quality of Life: Sub-analysis of the MICHEL Study Open
Paclitaxel administration affected activities of daily living through CIPN and symptoms were primarily noted in the hands and feet with regard to fine motor hand movements and mobility. Individualized care, potentially with duloxetine or r…
View article: A novel, synthesized, amphiphilic ethylene glycol squalene derivative suppresses BBN-induced bladder carcinogenesis
A novel, synthesized, amphiphilic ethylene glycol squalene derivative suppresses BBN-induced bladder carcinogenesis Open
Squalene, a natural triterpene with antioxidant, anti-inflammatory, and immunostimulatory properties, holds promise for cancer therapy. Here, we examined a previously developed, diethylene glycol derivative of squalene (SQ-diEG) and invest…
View article: A Clinical Trial to Evaluate the Safety and Efficacy of <scp><i>Centella asiatica</i></scp> for Ulcerative Colitis
A Clinical Trial to Evaluate the Safety and Efficacy of <span><i>Centella asiatica</i></span> for Ulcerative Colitis Open
Aims We previously reported that telomerase activator Centella asiatica (CA) can normalize the crypt structure of human colonic organoids in an ulcerative colitis (UC) model. Therefore, we aimed to evaluate the safety and efficacy of CA fo…
View article: Refining Compression Therapy for the Prevention of Peripheral Neuropathy in Breast Cancer Patients: Sub- analyses of a Patient Survey
Refining Compression Therapy for the Prevention of Peripheral Neuropathy in Breast Cancer Patients: Sub- analyses of a Patient Survey Open
Background: Taxane-induced peripheral neuropathy (TIPN) is a common and debilitating side effect of chemotherapy in breast cancer patients. Previous findings suggest that compression therapy may be a safe and effective preventive strategy …
View article: A novel, synthesized, amphiphilic ethylene glycol squalene derivative suppresses BBN-induced bladder carcinogenesis
A novel, synthesized, amphiphilic ethylene glycol squalene derivative suppresses BBN-induced bladder carcinogenesis Open
Squalene, a natural triterpene with antioxidant, anti-inflammatory, and immunostimulatory properties, holds promise for cancer therapy. Here, we examined a previously developed, diethylene glycol derivative of squalene (SQ-diEG) and invest…
View article: The Image Clarity Paradox: Higher CZT SPECT Contrast Does Not Always Translate to Diagnostic Accuracy for Alzheimer’s Disease
The Image Clarity Paradox: Higher CZT SPECT Contrast Does Not Always Translate to Diagnostic Accuracy for Alzheimer’s Disease Open
Background: Recent advances in single-photon emission computed tomography (SPECT) technology, particularly cadmium–zinc–telluride (CZT) detectors, have improved spatial resolution and contrast in cerebral blood flow imaging. This study aim…
View article: Successfully repaired adult cor triatriatum with mitral regurgitation and atrial fibrillation: a case report
Successfully repaired adult cor triatriatum with mitral regurgitation and atrial fibrillation: a case report Open
Background Rarely seen in adults, cor triatriatum is a congenital defect in which a membrane creates three atrial chambers in the heart. Atrial fibrillation (AF) is the most common complication, but repair procedures in adults remain unest…
View article: A Case of Secondary Extramammary Paget's Disease Surrounding a Cutaneous Ureterostoma After Recurrence of Bladder Urothelial Carcinoma
A Case of Secondary Extramammary Paget's Disease Surrounding a Cutaneous Ureterostoma After Recurrence of Bladder Urothelial Carcinoma Open
Introduction Secondary extramammary Paget's disease features intraepidermal carcinoma caused by tumor invasion and migration into adjacent skin. Case Presentation A 68‐year‐old man underwent radical cystectomy and bilateral cutaneous urete…
View article: A case of cerebral infarction caused by carbon dioxide embolism during robotic-assisted laparoscopic partial nephrectomy
A case of cerebral infarction caused by carbon dioxide embolism during robotic-assisted laparoscopic partial nephrectomy Open
Robot-assisted partial nephrectomy (RAPN) is a common, minimally invasive procedure for localized renal tumors but carries a rare risk of life-threatening CO2 embolism. We report an 83-year-old man who developed cerebral embolism from pulm…