Bryan P. Simpson
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View article: Targeted long-read sequencing captures CRISPR editing and AAV integration outcomes in brain
Targeted long-read sequencing captures CRISPR editing and AAV integration outcomes in brain Open
View article: 252. Using Cre-Dependent In Vivo Selection to Identify AAV Variants That Enable Efficient and Widespread Gene Transfer to the Adult Central Nervous System
252. Using Cre-Dependent In Vivo Selection to Identify AAV Variants That Enable Efficient and Widespread Gene Transfer to the Adult Central Nervous System Open
Recombinant adeno-associated viruses (rAAVs) are commonly
\nused vehicles for in vivo gene transfer. However, the tropism
\nrepertoire of naturally occurring AAVs is limited, prompting the
\ndevelopment of novel AAV capsids with more desir…
View article: Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain
Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain Open