Bryan Thiroux
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View article: Upregulation of adenosine A2A receptor in astrocytes is sufficient to trigger hippocampal multicellular dysfunctions and memory deficits
Upregulation of adenosine A2A receptor in astrocytes is sufficient to trigger hippocampal multicellular dysfunctions and memory deficits Open
View article: Inactivated Toxoplasma gondii nanovaccine boosts T-cell memory response in a seropositive yellow-footed rock wallaby (Petrogale xanthopus) – A case report from Copenhagen Zoo
Inactivated Toxoplasma gondii nanovaccine boosts T-cell memory response in a seropositive yellow-footed rock wallaby (Petrogale xanthopus) – A case report from Copenhagen Zoo Open
Toxoplasma gondii is a ubiquitous parasite causing significant mortality in captive wildlife, especially marsupials. Historically, treatment has been unrewarding and no vaccine was available. An intranasal vaccine based on purified …
View article: Upregulation of adenosine A2A receptor by astrocytes is sufficient to trigger hippocampal multicellular dysfunctions and memory deficits.
Upregulation of adenosine A2A receptor by astrocytes is sufficient to trigger hippocampal multicellular dysfunctions and memory deficits. Open
Adenosine is an ubiquitous neuromodulator that ensures cerebral homeostasis. It exerts numerous functions through the activation of G-protein-coupled adenosine receptors (ARs), in particular A1 (A1R) and A2A
View article: Neuronal A2A receptor exacerbates synapse loss and memory deficits in APP/PS1 mice
Neuronal A2A receptor exacerbates synapse loss and memory deficits in APP/PS1 mice Open
Early pathological upregulation of adenosine A2A receptors (A2ARs), one of the caffeine targets, by neurons is thought to be involved in the development of synaptic and memory deficits in Alzheimer’s disease (AD) but mechanisms remain ill-…
View article: Impaired Glucose Homeostasis in a Tau Knock-In Mouse Model
Impaired Glucose Homeostasis in a Tau Knock-In Mouse Model Open
Alzheimer’s disease (AD) is the leading cause of dementia. While impaired glucose homeostasis has been shown to increase AD risk and pathological loss of tau function, the latter has been suggested to contribute to the emergence of the glu…
View article: Impact of chronic doxycycline treatment in the APP/PS1 mouse model of Alzheimer's disease
Impact of chronic doxycycline treatment in the APP/PS1 mouse model of Alzheimer's disease Open