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View article: The Role of Nutrition in Endometriosis Prevention and Management: A Comprehensive Review.
The Role of Nutrition in Endometriosis Prevention and Management: A Comprehensive Review. Open
Endometriosis is a chronic gynecological condition defined by the ectopic presence of endometrial-like tissue outside the uterine cavity, often resulting in debilitating symptoms and significant impacts on quality of life. While the exact …
View article: rs4889 and rs5782018 polymorphisms of KISS1 gene as genetic predisposing factor for PCOS in Indonesian women
rs4889 and rs5782018 polymorphisms of KISS1 gene as genetic predisposing factor for PCOS in Indonesian women Open
* Background A disruption in the function of the HPG axis in PCOS causes increased frequency and amplitude of gonadotropin-releasing hormone (GnRH) pulsatility in the hypothalamus. Single nucleotide polymorphisms (SNPs) in the KISS1 gene m…
View article: Long COVID in vaccinated women with Polycystic Ovary Syndrome: A retrospective cohort pilot study
Long COVID in vaccinated women with Polycystic Ovary Syndrome: A retrospective cohort pilot study Open
HIGHLIGHTS Among women with PCOS, many still reported persistent long COVID symptoms such as hair loss and fatigue. COVID-19 vaccination does not exacerbate symptoms of PCOS, which further emphasizes the importance of completing COVID-19 d…
View article: Cellular, histological, and gene expression differences in thin versus normal endometrium
Cellular, histological, and gene expression differences in thin versus normal endometrium Open
Background: Endometrium disorders cause significant failure in fertility. Our study aimed to investigate the cellular, histological, and molecular properties of patients with thin endometrium compared to healthy endometrium without patholo…
View article: Comparing Dydrogesterone Versus Medroxyprogesterone in Progestin-Primed Ovarian Stimulation (PPOS) for Patients Undergoing In Vitro Fertilization/Intracytoplasmic Sperm Injection: A Systematic Review
Comparing Dydrogesterone Versus Medroxyprogesterone in Progestin-Primed Ovarian Stimulation (PPOS) for Patients Undergoing In Vitro Fertilization/Intracytoplasmic Sperm Injection: A Systematic Review Open
Dydrogesterone (DYG) in the progestin-primed ovarian stimulation (PPOS) protocol is an alternative progestin with weaker pituitary suppression than medroxyprogesterone acetate (MPA) in women with normal ovulation. However, the endocrinolog…
View article: Ovarian Tissue Cryopreservation in Patients with Endometriosis: A Systematic Review of the Literature
Ovarian Tissue Cryopreservation in Patients with Endometriosis: A Systematic Review of the Literature Open
View article: Knowledge, Attitude, and Perception Towards Condom Use among Female Sex Workers in North Jakarta: A Mixed-Method Study
Knowledge, Attitude, and Perception Towards Condom Use among Female Sex Workers in North Jakarta: A Mixed-Method Study Open
Background: HIV/AIDS is a significant global health and social issue, particularly affecting sex workers, who are the second most common high-risk population. Efforts have been attempted to address the challenges, including promoting safer…
View article: Embryo Mosaicism Rate in National Referral Hospital of Indonesia Detected Using Next-Generation Sequencing: A Retrospective Study.
Embryo Mosaicism Rate in National Referral Hospital of Indonesia Detected Using Next-Generation Sequencing: A Retrospective Study. Open
In contrast to the study conducted elsewhere, our center had a higher mosaicism rate. Chromosomes 9, 8, and 6 were the most frequently affected. There was a significant difference in the high mosaicism rate for PGT-Arelated unexplained inf…
View article: Geospatial Access to Emergency Obstetric Surgery in Indonesia: Is Travel Time for Access Too Long?
Geospatial Access to Emergency Obstetric Surgery in Indonesia: Is Travel Time for Access Too Long? Open
Background: Ensuring timely access to safe and affordable surgery within a travel time of a 2-h drive or 30-min walk is crucial for achieving universal health coverage, as endorsed by the Lancet Commission on Global Surgery (LCoGS). In thi…
View article: The relationship between non-communicable disease risk and mental wellbeing in adolescence: a cross-sectional study utilising objective measures in Indonesia
The relationship between non-communicable disease risk and mental wellbeing in adolescence: a cross-sectional study utilising objective measures in Indonesia Open
View article: Effects of autologous platelet-rich plasma in promoting endometrial thickness on patients with thin endometrium following IVF
Effects of autologous platelet-rich plasma in promoting endometrial thickness on patients with thin endometrium following IVF Open
HIGHLIGHTS It was observed that autologous PRP substantially increased endometrial thickness in individuals experiencing infertility linked to a thin endometrium. The elevated clinical pregnancy rate emphasizes the favorable effectiveness …
View article: Patient-centered endometriosis care implementation at tertiary and secondary care hospitals in Indonesia
Patient-centered endometriosis care implementation at tertiary and secondary care hospitals in Indonesia Open
View article: Elevated MMP-9, Survivin, TGB1 and Downregulated Tissue Inhibitor of TIMP-1, Caspase-3 Activities are Independent of the Low Levels miR-183 in Endometriosis
Elevated MMP-9, Survivin, TGB1 and Downregulated Tissue Inhibitor of TIMP-1, Caspase-3 Activities are Independent of the Low Levels miR-183 in Endometriosis Open
Despite the difference in expression levels of miR-183 and associated adhesion- and apoptosis-related genes, there was no significant association between miR-183 with specific adhesion and apoptosis genes in endometriosis tissue.
View article: In Vitro Fertilization (IVF) Outcomes in Patients With Endometriosis Compared to Patients With Tubal Factor Infertility in Indonesia: A Retrospective Study
In Vitro Fertilization (IVF) Outcomes in Patients With Endometriosis Compared to Patients With Tubal Factor Infertility in Indonesia: A Retrospective Study Open
View article: The relationship between non-communicable disease risks and mental wellbeing in adolescence: a cross-sectional study utilising objective measures in Indonesia
The relationship between non-communicable disease risks and mental wellbeing in adolescence: a cross-sectional study utilising objective measures in Indonesia Open
Background Risk factors for non-communicable diseases (NCDs, cardiovascular diseases, cancers, chronic respiratory diseases, diabetes, and mental disorders) arise in adolescence but are mostly framed as relevant to health in adulthood; lit…
View article: Effect of omega-3 fatty acids on endometriosis: A systematic review
Effect of omega-3 fatty acids on endometriosis: A systematic review Open
Introduction: Endometriosis is a term for an inflammatory condition where endometrium tissue develops outside the uterus. Endometriosis affects about 190 million reproductive-aged women. While medical and surgical therapies are essential, …
View article: Peripheral Serum AMH Level Reflects the Size of the Follicle Pool in a Mouse Model Study
Peripheral Serum AMH Level Reflects the Size of the Follicle Pool in a Mouse Model Study Open
Objective: This is to compare peripheral and central serum levels of Anti-Mullerian hormone (AMH) in experimental animals for predicting ovarian reserve. Methods: This is an experimental study involving 20 female Sprague-Dawley rats aged 8…
View article: The efficacy of luteal phase support in women with polycystic ovary syndrome following assisted reproductive technology: a systematic review
The efficacy of luteal phase support in women with polycystic ovary syndrome following assisted reproductive technology: a systematic review Open
Background Polycystic ovary syndrome (PCOS) is a complex endocrine condition prevalent among a significant number of women during their reproductive years. Remarkably, 90–95% of women seeking infertility solutions due to anovulation are di…
View article: Forecasting the Effects of Platelet-Rich Plasma on Follicle Development Following Premature Ovarian Insufficiency by Network Interaction Analysis
Forecasting the Effects of Platelet-Rich Plasma on Follicle Development Following Premature Ovarian Insufficiency by Network Interaction Analysis Open
Background and Objective: Platelet-Rich Plasma (PRP) is proposed to have a potential regenerative effect on the ovaries following premature ovarian insufficiency (POI), however, the main impact on the process of follicle development…
View article: The Efficacy and Safety of DLBS3233, A Combined Bioactive Fraction of <i>Cinnamomum burmanii</i> and <i>Lagerstroemia</i> speciosa Plants on The Endocrine-Metabolic Profile of Women with Polycystic Ovary Syndrome: A Randomized Clinical Trial.
The Efficacy and Safety of DLBS3233, A Combined Bioactive Fraction of <i>Cinnamomum burmanii</i> and <i>Lagerstroemia</i> speciosa Plants on The Endocrine-Metabolic Profile of Women with Polycystic Ovary Syndrome: A Randomized Clinical Trial. Open
Treatment with DLBS3233 100-mg daily in PCOS women demonstrated comparable efficacy to metformin- XR 750-mg twice daily in improving insulin resistance. However, the non-inferiority of DLBS3233 to metformin- XR remains inconclusive. DLBS32…
View article: Improving Deep Learning-Based Algorithm for Ploidy Status Prediction Through Combined U-NET Blastocyst Segmentation and Sequential Time-Lapse Blastocysts Images
Improving Deep Learning-Based Algorithm for Ploidy Status Prediction Through Combined U-NET Blastocyst Segmentation and Sequential Time-Lapse Blastocysts Images Open
Background: Several approaches have been proposed to optimize the construction of an artificial intelligence-based model for assessing ploidy status. These encompass the investigation of algorithms, refining image segmentation techniques, …
View article: Utilisation of Oocyte Diameter as a Non-invasive Indicator of Oocyte and Embryo Quality: Investigating Protein Kinase B Protein Expression in Cumulus–Granulosa Cells and Embryo Morphokinetics
Utilisation of Oocyte Diameter as a Non-invasive Indicator of Oocyte and Embryo Quality: Investigating Protein Kinase B Protein Expression in Cumulus–Granulosa Cells and Embryo Morphokinetics Open
Background: Oocyte diameter is crucial for initiating meiosis and supporting the maturation capability, a prerequisite for successful fertilisation and high-quality embryo development. While numerous studies have explored the correlation b…
View article: Endometriosis Care in the Indonesian Healthcare Referral System: Evaluating Diagnostic Delays and Therapeutic Approaches
Endometriosis Care in the Indonesian Healthcare Referral System: Evaluating Diagnostic Delays and Therapeutic Approaches Open
Background Endometriosis, a prevalent gynecological disorder, poses significant challenges in diagnosis and treatment, often leading to delayed care and compromised quality of life. With the implementation of the Indonesian National Health…
View article: Vitrification alters growth differentiation factor 9 and follicle-stimulating hormone receptor expression in human cumulus-mural granulosa cells
Vitrification alters growth differentiation factor 9 and follicle-stimulating hormone receptor expression in human cumulus-mural granulosa cells Open
Objective: Ovarian tissue vitrification is widely utilized for fertility preservation in prepubertal and adolescent female patients with cancer. The current literature includes reports of successful pregnancy and live birth following autog…
View article: The state of Continuing Professional Development in East and Southeast Asia among the medical practitioners
The state of Continuing Professional Development in East and Southeast Asia among the medical practitioners Open
Introduction: Continuing medical education and continuing professional development activities (CME/CPD) improve the practice of medical practitioners and allowing them to deliver quality clinical care. However, the systems that oversee CME…
View article: Immature oocyte proportion in a cohort led to poor embryo development but did not reduce clinical pregnancy rate
Immature oocyte proportion in a cohort led to poor embryo development but did not reduce clinical pregnancy rate Open
Purpose This study aimed to evaluate the effects of immature oocyte proportion in a cohort on both IVF laboratory and clinical outcomes. Materials and methods This retrospective cohort study took place at Morula IVF Jakarta Clinic from Jan…
View article: Implementation of Robson classification for caesarean section using health insurance claims: the experience of Indonesia
Implementation of Robson classification for caesarean section using health insurance claims: the experience of Indonesia Open
Robson classification has been recommended by the World Health Organization (WHO) as a monitoring tool for caesarean section (CS), however, it has not been implemented in Indonesia. In this study, we hypothesize that the National Health In…
View article: Intrauterine insemination and in vitro fertilization in serodiscordant couples with HIV-negative female partners
Intrauterine insemination and in vitro fertilization in serodiscordant couples with HIV-negative female partners Open
Introduction: Couples with HIV-infected male and non-HIV-infected female partners, also known as HIV serodiscordant couples, have a greater risk in planning a pregnancy. Assisted reproductive technology (ART), such as intrauterine insemina…
View article: Mechanism of elevated LH/FSH ratio in lean PCOS revisited: a path analysis
Mechanism of elevated LH/FSH ratio in lean PCOS revisited: a path analysis Open
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting 5–20% of reproductive-age women. However, the treatment of PCOS is mainly based on symptoms and not on its pathophysiology. Neuroendocrine disturbance, as sho…
View article: The Efficacy of Luteal Phase Support in Women with Polycystic Ovary Syndrome Following Assisted Reproductive Technology: A Systematic Review
The Efficacy of Luteal Phase Support in Women with Polycystic Ovary Syndrome Following Assisted Reproductive Technology: A Systematic Review Open