Bumhee Yang
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View article: Spirometry-Defined Restriction Modifies the Association between Forced Vital Capacity and Bronchiectasis Exacerbation
Spirometry-Defined Restriction Modifies the Association between Forced Vital Capacity and Bronchiectasis Exacerbation Open
Background: Obstructive ventilatory defect (OVD) is the most common ventilatory pattern in bronchiectasis, with low forced expiratory volume in 1 second (FEV1), which is a well-known risk factor for acute exacerbation (AE). However, the im…
View article: Rheumatoid arthritis and risk of non-tuberculous mycobacterial pulmonary disease: a nationwide longitudinal cohort study
Rheumatoid arthritis and risk of non-tuberculous mycobacterial pulmonary disease: a nationwide longitudinal cohort study Open
Background Previous literature suggested that rheumatoid arthritis (RA) might be a risk factor for nontuberculous mycobacteria pulmonary disease (NTM-PD). However, longitudinal studies did not comprehensively consider potential confounders…
View article: Bronchoalveolar lavage proteomics in exacerbation of bronchiectasis
Bronchoalveolar lavage proteomics in exacerbation of bronchiectasis Open
The bronchoalveolar lavage fluid protein expression in patients in the exacerbation status of bronchiectasis was significantly different from that in patients in the stable status, indicating that neutrophil degranulation and C-type lectin…
View article: #2701 Influenza vaccination uptake and determinants among korean chronic kidney disease patients: a nationwide cohort analysis
#2701 Influenza vaccination uptake and determinants among korean chronic kidney disease patients: a nationwide cohort analysis Open
Background and Aims Seasonal influenza poses a significant health threat worldwide, particularly among chronic kidney disease (CKD) patients with compromised immunity, who experience heightened morbidity and mortality. Despite universal re…
View article: Risk of pneumonia in individuals with rheumatoid arthritis: a nationwide cohort study
Risk of pneumonia in individuals with rheumatoid arthritis: a nationwide cohort study Open
Background Limited information is available on the influence of serologic status and different types of disease-modifying antirheumatic drugs (DMARDs) on risk of pneumonia. This study aimed to evaluate the risk of pneumonia according to rh…
View article: Unrecognized Tuberculosis: Risk Factors for Smear-Positive/Cavitary Asymptomatic Cases
Unrecognized Tuberculosis: Risk Factors for Smear-Positive/Cavitary Asymptomatic Cases Open
Background Screening patients with asymptomatic active tuberculosis (TB) is crucial as they can transmit the disease. Identifying the risk factors for transmission is essential for targeted screening. Understanding how the infectiousness o…
View article: Impact of physical activity on all-cause mortality in individuals with non-cystic fibrosis bronchiectasis
Impact of physical activity on all-cause mortality in individuals with non-cystic fibrosis bronchiectasis Open
Background Little information is available regarding whether active physical activity lowers mortality risk in individuals with bronchiectasis. Methods We used the Korean National Health Insurance Service database from 2010 to 2016 to eval…
View article: Exacerbation and mortality risk in individuals with bronchiectasis post-COVID-19 recovery
Exacerbation and mortality risk in individuals with bronchiectasis post-COVID-19 recovery Open
Background Individuals with bronchiectasis have an increased risk of exacerbation by coronavirus 2019 (COVID-19), even after recovery from COVID-19. However, the impact of COVID-19 severity on severe exacerbation and mortality remains unce…
View article: Hospitalization, Underweight, Depression, and Cancer Increase the Risk of Suicide in Individuals With Bronchiectasis
Hospitalization, Underweight, Depression, and Cancer Increase the Risk of Suicide in Individuals With Bronchiectasis Open
Bronchiectasis is commonly comorbid with depression and anxiety; therefore, bronchiectasis may be associated with an increased risk of suicide. We aimed to investigate whether suicidal risk is higher in individuals with bronchiectasis. We …
View article: Influenza Vaccination Trends and Associated Factors Among Middle-aged Working Adults With an Elevated Cardiovascular Risk in Korea
Influenza Vaccination Trends and Associated Factors Among Middle-aged Working Adults With an Elevated Cardiovascular Risk in Korea Open
One in 3 middle-aged working adults with an elevated risk of ASCVD received the influenza vaccination. Although the influenza vaccination rate was higher in participants with an elevated ASCVD risk than in those with low ASCVD risk, the va…
View article: Bronchoalveolar Lavage Proteomics in Acute Exacerbation of Bronchiectasis
Bronchoalveolar Lavage Proteomics in Acute Exacerbation of Bronchiectasis Open
Background: The molecular pathophysiology underlying the development of bronchiectasis with acute exacerbation at the proteomic level has not been clarified using bronchoalveolar lavage fluid samples. This study aimed to evaluate the bronc…
View article: Mucus plugging, disease severity and sputum myeloperoxidase concentration in bronchiectasis
Mucus plugging, disease severity and sputum myeloperoxidase concentration in bronchiectasis Open
Background Bronchiectasis is characterised by impaired mucociliary clearance, leading to persistent mucus accumulation, known as mucus plugging (MP). Myeloperoxidase (MPO) is a key molecule that activates neutrophilic inflammation during b…
View article: Large inferior vena cava thrombosis in a 25-year-old female patient: A case report
Large inferior vena cava thrombosis in a 25-year-old female patient: A case report Open
Rationale: The incidence of venous thromboembolism is increasing, and it is more common in older than in younger patients. Inferior vena cava (IVC) thrombosis is a rare subtype of deep vein thrombosis, and it is associated with a high inci…
View article: Rheumatoid Arthritis and Risk of Nontuberculous Mycobacterial Pulmonary Disease: A Nationwide Longitudinal Cohort Study
Rheumatoid Arthritis and Risk of Nontuberculous Mycobacterial Pulmonary Disease: A Nationwide Longitudinal Cohort Study Open
Background In this study, we aimed to evaluate the risk of incident nontuberculous mycobacteria pulmonary disease (NTM-PD) in subjects with rheumatoid arthritis (RA) versus age- and sex-matched controls, while focusing on the impact of RA …
View article: Tuberculosis survivors and the risk of cardiovascular disease: analysis using a nationwide survey in Korea
Tuberculosis survivors and the risk of cardiovascular disease: analysis using a nationwide survey in Korea Open
Background Although the association between tuberculosis (TB) and cardiovascular disease (CVD) has been reported in several studies and is explained by mechanisms related to chronic inflammation, few studies have comprehensively evaluated …
View article: National trend in the prevalence and mortality of COPD in South Korea from 2008 to 2017
National trend in the prevalence and mortality of COPD in South Korea from 2008 to 2017 Open
Background Existing studies on chronic obstructive pulmonary disease (COPD) in Korea lack full population coverage, relying on small sample sizes. Therefore, this study aims to investigate the prevalence and mortality of COPD in the entire…
View article: A prospective, open-label, randomized clinical trial to evaluate the efficacy and safety of remimazolam in patients undergoing EBUS-TBNA: REST trial design
A prospective, open-label, randomized clinical trial to evaluate the efficacy and safety of remimazolam in patients undergoing EBUS-TBNA: REST trial design Open
Background Remimazolam is safe and effective for moderate sedation during flexible bronchoscopy, but its safety and efficacy during endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) remains undetermined. The REST…
View article: Increased bronchiectasis risk and related risk factors in inflammatory bowel disease: a 10-year Korean national cohort study
Increased bronchiectasis risk and related risk factors in inflammatory bowel disease: a 10-year Korean national cohort study Open
Background The association between inflammatory bowel disease (IBD) and an increased risk of bronchiectasis, as well as contributing factors, remains unclear. Additionally, whether bronchiectasis increases disease burden in IBD remains unk…
View article: Impacts of regular physical activity on hospitalisation in chronic obstructive pulmonary disease: a nationwide population-based study
Impacts of regular physical activity on hospitalisation in chronic obstructive pulmonary disease: a nationwide population-based study Open
Introduction Studies that comprehensively evaluate the association between physical activity (PA) levels, particularly by quantifying PA intensity, and healthcare use requiring emergency department (ED) visit or hospitalisation in patients…
View article: Timely Pulmonary Tuberculosis Diagnosis Based on the Epidemiological Disease Spectrum: Population-Based Prospective Cohort Study in the Republic of Korea
Timely Pulmonary Tuberculosis Diagnosis Based on the Epidemiological Disease Spectrum: Population-Based Prospective Cohort Study in the Republic of Korea Open
Background Timely pulmonary tuberculosis (PTB) diagnosis is a global health priority for interrupting transmission and optimizing treatment outcomes. The traditional dichotomous time-divided approach for addressing time delays in diagnosis…
View article: Glycemic Control and Oral Health Outcomes in Patients With Diabetes: Insights From a Nationwide Korean Survey
Glycemic Control and Oral Health Outcomes in Patients With Diabetes: Insights From a Nationwide Korean Survey Open
We found a positive association between diabetes and poor oral health, as well as a noteworthy relationship between reduced permanent teeth (≤ 19) and glycemic control. These insights emphasize the critical role of oral health management i…
View article: Increased Risk of Incident Chronic Obstructive Pulmonary Disease and Related Hospitalizations in Tuberculosis Survivors: A Population-Based Matched Cohort Study
Increased Risk of Incident Chronic Obstructive Pulmonary Disease and Related Hospitalizations in Tuberculosis Survivors: A Population-Based Matched Cohort Study Open
BACKGROUND: Tuberculosis (TB) survivors have an increased risk of developing chronic obstructive pulmonary disease (COPD). This study assessed the risk of COPD development and COPD-related hospitalization in TB survivors compared to contro…
View article: Characteristics of subclinical tuberculosis compared to active symptomatic tuberculosis using nationwide registry cohort in Korea: prospective cohort study
Characteristics of subclinical tuberculosis compared to active symptomatic tuberculosis using nationwide registry cohort in Korea: prospective cohort study Open
Objective The clinical manifestations of tuberculosis (TB) range from asymptomatic to disseminated depending on the microbiological and immunological status, making the diagnosis challenging. To improve our understanding of the disease pro…