Buxing Chen
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View article: Combined triglyceride-glucose index and systemic inflammation response index are associated with coronary artery stenosis severity in acute coronary syndrome: a retrospective cohort study
Combined triglyceride-glucose index and systemic inflammation response index are associated with coronary artery stenosis severity in acute coronary syndrome: a retrospective cohort study Open
The combination of TyG and SIRI is strongly associated with coronary stenosis severity in ACS patients, suggesting its potential as a clinically feasible, non-invasive indicator for early risk stratification.
View article: Advantages of hybrid intravascular ultrasound-optical coherence tomography system in clinical practice
Advantages of hybrid intravascular ultrasound-optical coherence tomography system in clinical practice Open
Background While the hybrid intravascular ultrasound-optical coherence tomography (IVUS-OCT) imaging system offers theoretical advantages for enhanced characterization of vascular morphology and histopathology through multimodal integratio…
View article: A Correlation Study on the Prediction of Coronary Artery Lesion Degree by Pulse Wave Harmonics Based on SYNTAX Score
A Correlation Study on the Prediction of Coronary Artery Lesion Degree by Pulse Wave Harmonics Based on SYNTAX Score Open
Objective This study aimed to investigate the correlation between the differences in pulse wave harmonic indexes between the left and right hands and the SYNTAX score, and to explore the potential of pulse wave harmonics in predicting the …
View article: Predicting Coronary Artery Lesion Severity using Pulse Wave Harmonics: A SYNTAX Score-based Study
Predicting Coronary Artery Lesion Severity using Pulse Wave Harmonics: A SYNTAX Score-based Study Open
Introduction: This study aimed to investigate the correlation between the differences in pulse wave harmonic indices between the left and right hands and the SYNTAX score and to explore the potential of pulse wave harmonics in predicting t…
View article: Exploring the Mechanism of Action of Berberine on Arrhythmia After Myocardial Infarction: A Network Pharmacology, Molecular Docking, and Cellular Experimental Study
Exploring the Mechanism of Action of Berberine on Arrhythmia After Myocardial Infarction: A Network Pharmacology, Molecular Docking, and Cellular Experimental Study Open
Background: Arrhythmia after myocardial infarction, a common disease, has a high incidence and lethality in clinical practice, which seriously affects patients’ quality of life and survival time. Based on our previous study and available e…
View article: The Associations of Gut Microbiota Metabolites with Blood Lipids and the Effect of Rosuvastatin Therapy on Them
The Associations of Gut Microbiota Metabolites with Blood Lipids and the Effect of Rosuvastatin Therapy on Them Open
Background: Gut microbiota is contributed to the variations of blood lipids, and statins are found to affect the gut microbiota compositions. The aims of this study were to evaluate the associations of trimethylamine N-oxide (TMAO) and rel…
View article: Soluble receptor for advanced glycation end-products enhanced the production of IFN-γ through the NF-κB pathway in macrophages recruited by ischemia/reperfusion
Soluble receptor for advanced glycation end-products enhanced the production of IFN-γ through the NF-κB pathway in macrophages recruited by ischemia/reperfusion Open
The current study investigated the role of sRAGE in the production of IFN‑γ in macrophages with I/R treatment. The number of macrophages in myocardial tissues treated with I/R with or without sRAGE was determined via immunohistochemical st…
View article: Change in lipoprotein-associated phospholipase A2 and its association with cardiovascular outcomes in patients with acute coronary syndrome
Change in lipoprotein-associated phospholipase A2 and its association with cardiovascular outcomes in patients with acute coronary syndrome Open
Lipoprotein-associated phospholipase A2 (Lp-PLA2) probably plays an important role in the development of acute coronary syndrome (ACS). However, alterations of Lp-PLA2 levels during ACS and its association with cardiovascular outcome are u…
View article: Assessment of patients’ warfarin knowledge and anticoagulation control at a joint physician- and pharmacist-managed clinic in China
Assessment of patients’ warfarin knowledge and anticoagulation control at a joint physician- and pharmacist-managed clinic in China Open
Areas for improvement in patient education have been identified, and processes for educational modification are currently in development.
View article: Thromboelastography evaluation of low response to clopidogrel in patients with acute coronary syndrome
Thromboelastography evaluation of low response to clopidogrel in patients with acute coronary syndrome Open
Summary: Background: This study aims to measure platelet aggregation with thromboelastography (TEG) and observe low response to clopidogrel in patients with acute coronary syndrome (ACS) receiving dual antiplatelet therapy. Methods: TEG wa…
View article: MOESM1 of Liraglutide downregulates hepatic LDL receptor and PCSK9 expression in HepG2 cells and db/db mice through a HNF-1a dependent mechanism
MOESM1 of Liraglutide downregulates hepatic LDL receptor and PCSK9 expression in HepG2 cells and db/db mice through a HNF-1a dependent mechanism Open
Additional file 1. Change in fasting glucose in db/db mice and nondiabetic mice.
View article: Electrocardiogram in patients with acute inferior myocardial infarction due to occlusion of circumflex artery
Electrocardiogram in patients with acute inferior myocardial infarction due to occlusion of circumflex artery Open
To investigate the diagnostic value of electrocardiographic (ECG) ST-segment in acute inferior myocardial infarction (AIMI) caused by the left circumflex branch (LCX).A total of 240 clinical cases with AIMI in our hospital were retrospecti…
View article: Comprehensive metabolomics identified lipid peroxidation as a prominent feature in human plasma of patients with coronary heart diseases
Comprehensive metabolomics identified lipid peroxidation as a prominent feature in human plasma of patients with coronary heart diseases Open
Coronary heart disease (CHD) is a complex human disease associated with inflammation and oxidative stress. The underlying mechanisms and diagnostic biomarkers for the different types of CHD remain poorly defined. Metabolomics has been incr…
View article: Trimethylamine N-oxide in atherogenesis: impairing endothelial self-repair capacity and enhancing monocyte adhesion
Trimethylamine N-oxide in atherogenesis: impairing endothelial self-repair capacity and enhancing monocyte adhesion Open
Several studies have reported a strong association between high plasma level of trimethylamine N-oxide (TMAO) and atherosclerosis development. However, the exact mechanism underlying this correlation is unknown. In the present study, we tr…
View article: Vascular response profiles following a nano polymer-free sirolimus-eluting stent implantation assessed by optical coherence tomography in a porcine model
Vascular response profiles following a nano polymer-free sirolimus-eluting stent implantation assessed by optical coherence tomography in a porcine model Open
Optical coherence tomography (OCT) is a high resolution imaging modality and has been considered as the ideal tool for the evaluation of neointimal tissue and vascular responses following stent implantation. However, vascular response prof…
View article: Young Paradoxical Stroke Treated Successfully with Mechanical Thrombectomy Using Solitaire and Transcatheter Closure of Patent Foramen Oval
Young Paradoxical Stroke Treated Successfully with Mechanical Thrombectomy Using Solitaire and Transcatheter Closure of Patent Foramen Oval Open
Paradoxical embolization is the mechanism for patent foramen ovale (PFO)-associated cryptogenic stroke and transcatheter closure of PFO may prevent recurrent ischemic stroke. Mechanical thrombectomy is promising to treat acute ischemic str…
View article: Relationship of coronary collateral circulation with eosinophils in patients with unstable angina pectoris
Relationship of coronary collateral circulation with eosinophils in patients with unstable angina pectoris Open
EOS were associated with high-grade CCC in patients with UAP with coronary stenosis ≥80%. Increased EOS count may play an important role in the development of CCC in patients with UAP.