Byron Sigel
YOU?
Author Swipe
View article: Quantify the Contribution of Modifiable Risk Factors for Progression of MGUS to Multiple Myeloma
Quantify the Contribution of Modifiable Risk Factors for Progression of MGUS to Multiple Myeloma Open
Background Multiple myeloma (MM), the most common plasma cell dyscrasia in the U.S., is preceded by an asymptomatic precursor monoclonal gammopathy of undetermined significance (MGUS). Although several risk factors for MGUS progression are…
View article: Adult brain cancer incidence patterns: A comparative study between Japan and Japanese Americans
Adult brain cancer incidence patterns: A comparative study between Japan and Japanese Americans Open
Adult primary brain and central nervous system (CNS) cancers, though comprising only about 4% of new cancer diagnoses, significantly impact morbidity and mortality due to their low survival rates. Globally, brain and CNS tumor incidence va…
View article: Cost‐effectiveness of preventive aspirin use and intensive downstaging polypectomy in patients with familial adenomatous polyposis: A microsimulation modeling study
Cost‐effectiveness of preventive aspirin use and intensive downstaging polypectomy in patients with familial adenomatous polyposis: A microsimulation modeling study Open
Objective Although there is increasing evidence to suggest the cost‐effectiveness of aspirin use to prevent colorectal cancer (CRC) in the general population, no study has assessed cost‐effectiveness in patients with familial adenomatous p…
View article: Salt intake reduction using umami substance-incorporated food: a secondary analysis of NHANES 2017–2018 data
Salt intake reduction using umami substance-incorporated food: a secondary analysis of NHANES 2017–2018 data Open
Objective: Excessive salt intake raises blood pressure and increases the risk of non-communicable diseases (NCD), such as CVD, chronic kidney disease and stomach cancer. Reducing the Na content of food is an important public health measure…
View article: Salt intake reduction using umami substance-incorporated food in the United States
Salt intake reduction using umami substance-incorporated food in the United States Open
Background Excessive salt intake has been linked to the development of several non-communicable diseases. Reducing the sodium content of foods is an important global public health activity to achieve salt reduction and health promotion. Th…
View article: Increasing hepatitis virus screening uptake at worksites in Japan using nudge theory and full subsidies
Increasing hepatitis virus screening uptake at worksites in Japan using nudge theory and full subsidies Open
Background Despite the importance of hepatitis screening for decreasing liver cancer mortality, screening rates remain low in Japan. Previous studies show that full subsidies increase screening uptake, but full subsidies are costly and dif…
View article: Subsequent Neoplasm Risk Associated With Rare Variants in DNA Damage Response and Clinical Radiation Sensitivity Syndrome Genes in the Childhood Cancer Survivor Study
Subsequent Neoplasm Risk Associated With Rare Variants in DNA Damage Response and Clinical Radiation Sensitivity Syndrome Genes in the Childhood Cancer Survivor Study Open
PURPOSE Radiotherapy for childhood cancer is associated with elevated subsequent neoplasm (SN) risk, but the contribution of rare variants in DNA damage response and radiation sensitivity genes to SN risk is unknown. PATIENTS AND METHODS W…
View article: Trends in Premature Deaths Among Adults in the United States and Latin America
Trends in Premature Deaths Among Adults in the United States and Latin America Open
Premature mortality rates are lower for US Latino populations and several Latin American countries than for US white populations, suggesting that there may be a broader Latin American paradox. This analysis also highlights the high prematu…
View article: Bone and Soft‐Tissue Sarcoma Risk in Long‐Term Survivors of Hereditary Retinoblastoma Treated With Radiation
Bone and Soft‐Tissue Sarcoma Risk in Long‐Term Survivors of Hereditary Retinoblastoma Treated With Radiation Open
PURPOSE Survivors of hereditary retinoblastoma have excellent survival but substantially increased risks of subsequent bone and soft-tissue sarcomas, particularly after radiotherapy. Comprehensive investigation of sarcoma risk patterns wou…
View article: Association of Chemotherapy for Solid Tumors With Development of Therapy-Related Myelodysplastic Syndrome or Acute Myeloid Leukemia in the Modern Era
Association of Chemotherapy for Solid Tumors With Development of Therapy-Related Myelodysplastic Syndrome or Acute Myeloid Leukemia in the Modern Era Open
Large-scale, United States population-based data demonstrate excess tMDS/AML risks following chemotherapy for nearly all solid tumor types, consistent with expanded use of known leukemogenic agents in the 21st century. Continued efforts to…
View article: Patterns of Cause-Specific Mortality Among 2053 Survivors of Retinoblastoma, 1914–2016
Patterns of Cause-Specific Mortality Among 2053 Survivors of Retinoblastoma, 1914–2016 Open
Background Previous studies of hereditary retinoblastoma survivors have reported elevated mortality, particularly for sarcomas, compared with the general population. However, cause-specific mortality patterns for long-term hereditary and n…