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View article: Empirical optimization of dual-sgRNA design for in vivo CRISPR/Cas9-mediated exon deletion in mice
Empirical optimization of dual-sgRNA design for in vivo CRISPR/Cas9-mediated exon deletion in mice Open
CRISPR/Cas9 has transformed gene editing, enabling precise genetic modifications across species. However, existing sgRNA design prediction models based on in vitro data are difficult to generalize to in vivo contexts. In particular, approa…
View article: Shielding Si Armed with CoSi <sub>2</sub> Nanoplates and Dual‐Carbon Shells: 3D Porous Microspheres as High‐Performance Anodes for Li‐Ion Batteries
Shielding Si Armed with CoSi <sub>2</sub> Nanoplates and Dual‐Carbon Shells: 3D Porous Microspheres as High‐Performance Anodes for Li‐Ion Batteries Open
In this study, a novel multi‐core–dual‐shell strategy is employed to synthesize 3D porous microspheres. These microspheres consist of Si armed with CoSi 2 nanoplates multi‐cores encapsulated within dual protective shells of metallic‐Co nan…
View article: Development and evaluation of modified lead gloves to reduce hand radiation dose during interventional radiological procedures
Development and evaluation of modified lead gloves to reduce hand radiation dose during interventional radiological procedures Open
We developed lead gloves that minimize radiation dose to the operator's hands during interventional radiological procedures and that do not impede the operator's surgical capabilities. Existing lead gloves can protect the operator's hands …
View article: A study on the positioning of fine scintillation pixels in a positron emission tomography detector through deep learning of simulation data
A study on the positioning of fine scintillation pixels in a positron emission tomography detector through deep learning of simulation data Open
In order to specify the location of the scintillation pixel that interacted with gamma rays in the positron emission tomography (PET) detector, conventionally, after acquiring a flood image, the location of interaction between the scintill…
View article: Feasibility Study of Robust Optimization to Reduce Dose Delivery Uncertainty by Potential Applicator Displacements for a Cervix Brachytherapy
Feasibility Study of Robust Optimization to Reduce Dose Delivery Uncertainty by Potential Applicator Displacements for a Cervix Brachytherapy Open
Brachytherapy is an important technique to increase the overall survival of cervical cancer patients. However, a possible shift of the applicators in relation to the target and organs at risk may occur between imaging and treatment. Withou…
View article: Facial expression monitoring system for predicting patient’s sudden movement during radiotherapy using deep learning
Facial expression monitoring system for predicting patient’s sudden movement during radiotherapy using deep learning Open
Purpose Imaging, breath‐holding/gating, and fixation devices have been developed to minimize setup errors so that the prescribed dose can be exactly delivered to the target volume in radiotherapy. Despite these efforts, additional patient …
View article: Robust Optimization to Reduce Dose Delivery Uncertainty by Potential Applicator Displacements for a Cervix Brachytherapy
Robust Optimization to Reduce Dose Delivery Uncertainty by Potential Applicator Displacements for a Cervix Brachytherapy Open
Background Applicator displacement during brachytherapy treatment for cervical cancer leads to a drastic change in dose distribution. Hence, applicator displacement uncertainty is of significant relevance within the distribution of dose pr…
View article: Feasibility study of shutter scan acquisition for region of interest (<scp>ROI</scp>) digital tomosynthesis
Feasibility study of shutter scan acquisition for region of interest (<span>ROI</span>) digital tomosynthesis Open
Dose reduction techniques have been studied in medical imaging. We propose shutter scan acquisition for region of interest ( ROI ) imaging to reduce the patient exposure dose received from a digital tomosynthesis system. A prototype chest …