Claire Andréjak
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View article: Management of latent TB infection: a national survey of French physicians
Management of latent TB infection: a national survey of French physicians Open
International audience
View article: Management of Nontuberculous Mycobacterial Pulmonary Disease Refractory to Guideline-Based Therapy: A Systematic Review
Management of Nontuberculous Mycobacterial Pulmonary Disease Refractory to Guideline-Based Therapy: A Systematic Review Open
Introduction Managing patients with nontuberculous mycobacterial pulmonary disease (NTM-PD) unresponsive to guideline-based therapy presents a significant clinical challenge. Limited treatment options and the complex nature of disease prog…
View article: Urgent request for pretomanid label expansion to align with WHO guidelines and improve treatment accessibility and efficacy
Urgent request for pretomanid label expansion to align with WHO guidelines and improve treatment accessibility and efficacy Open
SUMMARY Pretomanid is a key anti-TB drug included in the WHO list of essential medications. The current EMA-approved label for pretomanid restricts its use to the regimen comprising bedaquiline, pretomanid and linezolid (BPaL) and only for…
View article: Efficacy and safety of tezepelumab versus placebo in adults with moderate to very severe chronic obstructive pulmonary disease (COURSE): a randomised, placebo-controlled, phase 2a trial
Efficacy and safety of tezepelumab versus placebo in adults with moderate to very severe chronic obstructive pulmonary disease (COURSE): a randomised, placebo-controlled, phase 2a trial Open
AstraZeneca and Amgen.
View article: Cardiac Adverse Events and Remdesivir in Hospitalized Patients With COVID-19: A Post Hoc Safety Analysis of the Randomized DisCoVeRy Trial
Cardiac Adverse Events and Remdesivir in Hospitalized Patients With COVID-19: A Post Hoc Safety Analysis of the Randomized DisCoVeRy Trial Open
Background We aimed to evaluate the cardiac adverse events (AEs) in hospitalized patients with coronavirus disease 2019 (COVID-19) who received remdesivir plus standard of care (SoC) compared with SoC alone (control), as an association was…
View article: Sex differences in post-acute neurological sequelae of SARS-CoV-2 and symptom resolution in adults after coronavirus disease 2019 hospitalization: an international multi-centre prospective observational study
Sex differences in post-acute neurological sequelae of SARS-CoV-2 and symptom resolution in adults after coronavirus disease 2019 hospitalization: an international multi-centre prospective observational study Open
Although it is known that coronavirus disease 2019 can present with a range of neurological manifestations and in-hospital complications, sparse data exist on whether these initial neurological symptoms of coronavirus disease 2019 are clos…
View article: Implementation of Recommendations on the Use of Corticosteroids in Severe COVID-19
Implementation of Recommendations on the Use of Corticosteroids in Severe COVID-19 Open
Importance Research diversity and representativeness are paramount in building trust, generating valid biomedical knowledge, and possibly in implementing clinical guidelines. Objectives To compare variations over time and across World Heal…
View article: Long-term outcomes of the global tuberculosis and COVID-19 co-infection cohort
Long-term outcomes of the global tuberculosis and COVID-19 co-infection cohort Open
Background Longitudinal cohort data of patients with tuberculosis (TB) and coronavirus disease 2019 (COVID-19) are lacking. In our global study, we describe long-term outcomes of patients affected by TB and COVID-19. Methods We collected d…
View article: Clinical standards for diagnosis, treatment and prevention of post-COVID-19 lung disease
Clinical standards for diagnosis, treatment and prevention of post-COVID-19 lung disease Open
BACKGROUND: The aim of these clinical standards is to provide guidance on ‘best practice’ care for the diagnosis, treatment and prevention of post-COVID-19 lung disease. METHODS: A panel of international experts representing scientific soc…
Inhaled corticosteroids and adverse outcomes among chronic obstructive pulmonary disease patients with community-acquired pneumonia: a population-based cohort study Open
Introduction While inhaled corticosteroids (ICS) may increase pneumonia risk in patients with chronic obstructive pulmonary disease (COPD), the impact of ICS on pneumonia outcomes is debated. We examined whether ICS use is associated with …
Respiratory recovery trajectories after severe-to-critical COVID-19: a 1-year prospective multicentre study Open
Background Survivors of severe-to-critical coronavirus disease 2019 (COVID-19) may have functional impairment, radiological sequelae and persistent symptoms requiring prolonged follow-up. This pragmatic study aimed to describe their clinic…
View article: Amikacin Liposomal Inhalation Suspension in the Treatment of <i>Mycobacterium abscessus</i> Lung Infection: A French Observational Experience
Amikacin Liposomal Inhalation Suspension in the Treatment of <i>Mycobacterium abscessus</i> Lung Infection: A French Observational Experience Open
Background Mycobacterium abscessus infections remain difficult to manage in both cystic fibrosis (CF) and non-CF patients and reported clinical outcomes are largely unsatisfactory. Clinical trial data are limited and no approved therapies …
View article: Neurological manifestations of COVID-19 in adults and children
Neurological manifestations of COVID-19 in adults and children Open
Different neurological manifestations of coronavirus disease 2019 (COVID-19) in adults and children and their impact have not been well characterized. We aimed to determine the prevalence of neurological manifestations and in-hospital comp…
Epidemiology of infection by pulmonary non-tuberculous mycobacteria in French Guiana 2008–2018 Open
Introduction Unlike diseases caused by Mycobacterium tuberculosis , M . leprae and M . ulcerans , the epidemiology of pulmonary non-tuberculous mycobacteria (PNTM) has not received due attention in French Guiana. The main objective of the …
No Impact of Corticosteroid Use During the Acute Phase on Persistent Symptoms Post-COVID-19 Open
Persistent COVID-19 symptoms may be related to residual inflammation, but no preventive treatment has been evaluated. This study aimed to analyze, in a prospective cohort, whether corticosteroid use in the acute phase of COVID-19 in hospit…