Laurence Desjardins
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View article: Conservative treatment using laser diode and systemic chemotherapy for early‐stage bilateral retinoblastoma: A 14‐year prospective cohort study
Conservative treatment using laser diode and systemic chemotherapy for early‐stage bilateral retinoblastoma: A 14‐year prospective cohort study Open
Background Solid evidence of the safety and effectiveness of retinoblastoma (RB) conservative treatment using thermotherapy and systemic chemotherapy with long‐term follow‐up is scarce, especially in low‐resource countries. Aims This study…
View article: Supplementary Figures S1-S7 from <i>SF3B1</i> Mutations Are Associated with Alternative Splicing in Uveal Melanoma
Supplementary Figures S1-S7 from <i>SF3B1</i> Mutations Are Associated with Alternative Splicing in Uveal Melanoma Open
Supplementary Figures S1-S7 - PDF file 4131K, This file contains Supplementary Figures S1-S7. S1 Summary of somatic copy number alterations in uveal melanoma S2 Circos plots of uveal melanoma genomes S3 Distribution of missense mutations i…
View article: Supplementary Tables 1-12 from <i>SF3B1</i> Mutations Are Associated with Alternative Splicing in Uveal Melanoma
Supplementary Tables 1-12 from <i>SF3B1</i> Mutations Are Associated with Alternative Splicing in Uveal Melanoma Open
Supplementary Tables 1-12 - XLSX file 156K, This file contains Supplementary Tables 1-12. Supplementary Table 1. Clinical information of 12 patients in discovery cohort. Supplementary Table 2. Whole genome sequnecing coverage of uveal mela…
View article: Data from <i>SF3B1</i> Mutations Are Associated with Alternative Splicing in Uveal Melanoma
Data from <i>SF3B1</i> Mutations Are Associated with Alternative Splicing in Uveal Melanoma Open
Uveal melanoma, the most common eye malignancy, causes severe visual morbidity and is fatal in approximately 50% of patients. Primary uveal melanoma can be cured by surgery or radiotherapy, but the metastatic disease is treatment refractor…
View article: Supplementary Tables 1-12 from <i>SF3B1</i> Mutations Are Associated with Alternative Splicing in Uveal Melanoma
Supplementary Tables 1-12 from <i>SF3B1</i> Mutations Are Associated with Alternative Splicing in Uveal Melanoma Open
Supplementary Tables 1-12 - XLSX file 156K, This file contains Supplementary Tables 1-12. Supplementary Table 1. Clinical information of 12 patients in discovery cohort. Supplementary Table 2. Whole genome sequnecing coverage of uveal mela…
View article: Supplementary Methods from <i>SF3B1</i> Mutations Are Associated with Alternative Splicing in Uveal Melanoma
Supplementary Methods from <i>SF3B1</i> Mutations Are Associated with Alternative Splicing in Uveal Melanoma Open
Supplementary Methods - PDF file 148K, Contains supplementary methods used in data analysis
View article: Supplementary Figures S1-S7 from <i>SF3B1</i> Mutations Are Associated with Alternative Splicing in Uveal Melanoma
Supplementary Figures S1-S7 from <i>SF3B1</i> Mutations Are Associated with Alternative Splicing in Uveal Melanoma Open
Supplementary Figures S1-S7 - PDF file 4131K, This file contains Supplementary Figures S1-S7. S1 Summary of somatic copy number alterations in uveal melanoma S2 Circos plots of uveal melanoma genomes S3 Distribution of missense mutations i…
View article: Data from <i>SF3B1</i> Mutations Are Associated with Alternative Splicing in Uveal Melanoma
Data from <i>SF3B1</i> Mutations Are Associated with Alternative Splicing in Uveal Melanoma Open
Uveal melanoma, the most common eye malignancy, causes severe visual morbidity and is fatal in approximately 50% of patients. Primary uveal melanoma can be cured by surgery or radiotherapy, but the metastatic disease is treatment refractor…
View article: Supplementary Methods from <i>SF3B1</i> Mutations Are Associated with Alternative Splicing in Uveal Melanoma
Supplementary Methods from <i>SF3B1</i> Mutations Are Associated with Alternative Splicing in Uveal Melanoma Open
Supplementary Methods - PDF file 148K, Contains supplementary methods used in data analysis
View article: Data from Pyrophosphorolysis-Activated Polymerization Detects Circulating Tumor DNA in Metastatic Uveal Melanoma
Data from Pyrophosphorolysis-Activated Polymerization Detects Circulating Tumor DNA in Metastatic Uveal Melanoma Open
Purpose: To develop a molecular tool to detect circulating tumor–derived DNA (ctDNA) in the plasma from patients with uveal melanoma as a marker of tumor burden and monitor treatment efficacy.Experimental Design: A real-time PCR was develo…
View article: Supplementary Table 1 from Pyrophosphorolysis-Activated Polymerization Detects Circulating Tumor DNA in Metastatic Uveal Melanoma
Supplementary Table 1 from Pyrophosphorolysis-Activated Polymerization Detects Circulating Tumor DNA in Metastatic Uveal Melanoma Open
PDF file, 26KB, Biological and imaging characteristics in the 21 metastatic uveal melanoma patients.
View article: Supplementary Figure 1 from Pyrophosphorolysis-Activated Polymerization Detects Circulating Tumor DNA in Metastatic Uveal Melanoma
Supplementary Figure 1 from Pyrophosphorolysis-Activated Polymerization Detects Circulating Tumor DNA in Metastatic Uveal Melanoma Open
PDF file, 32KB, Correlation between ctDNA and cfcDNA levels in UM patients.
View article: Data from Establishment and Characterization of a Panel of Human Uveal Melanoma Xenografts Derived from Primary and/or Metastatic Tumors
Data from Establishment and Characterization of a Panel of Human Uveal Melanoma Xenografts Derived from Primary and/or Metastatic Tumors Open
Purpose: Uveal melanoma is the most common primary intraocular malignant tumor in adults and is defined by a poor natural outcome, as 50% of patients die from metastases. The aim of this study was to develop and characterize a panel of hum…
View article: Supplementary Table 1 from Pyrophosphorolysis-Activated Polymerization Detects Circulating Tumor DNA in Metastatic Uveal Melanoma
Supplementary Table 1 from Pyrophosphorolysis-Activated Polymerization Detects Circulating Tumor DNA in Metastatic Uveal Melanoma Open
PDF file, 26KB, Biological and imaging characteristics in the 21 metastatic uveal melanoma patients.
View article: Supplementary Figure 1 from Pyrophosphorolysis-Activated Polymerization Detects Circulating Tumor DNA in Metastatic Uveal Melanoma
Supplementary Figure 1 from Pyrophosphorolysis-Activated Polymerization Detects Circulating Tumor DNA in Metastatic Uveal Melanoma Open
PDF file, 32KB, Correlation between ctDNA and cfcDNA levels in UM patients.
View article: Supplementary Data from Establishment and Characterization of a Panel of Human Uveal Melanoma Xenografts Derived from Primary and/or Metastatic Tumors
Supplementary Data from Establishment and Characterization of a Panel of Human Uveal Melanoma Xenografts Derived from Primary and/or Metastatic Tumors Open
Supplementary Data from Establishment and Characterization of a Panel of Human Uveal Melanoma Xenografts Derived from Primary and/or Metastatic Tumors
View article: Data from Establishment and Characterization of a Panel of Human Uveal Melanoma Xenografts Derived from Primary and/or Metastatic Tumors
Data from Establishment and Characterization of a Panel of Human Uveal Melanoma Xenografts Derived from Primary and/or Metastatic Tumors Open
Purpose: Uveal melanoma is the most common primary intraocular malignant tumor in adults and is defined by a poor natural outcome, as 50% of patients die from metastases. The aim of this study was to develop and characterize a panel of hum…
View article: Data from Pyrophosphorolysis-Activated Polymerization Detects Circulating Tumor DNA in Metastatic Uveal Melanoma
Data from Pyrophosphorolysis-Activated Polymerization Detects Circulating Tumor DNA in Metastatic Uveal Melanoma Open
Purpose: To develop a molecular tool to detect circulating tumor–derived DNA (ctDNA) in the plasma from patients with uveal melanoma as a marker of tumor burden and monitor treatment efficacy.Experimental Design: A real-time PCR was develo…
View article: Supplementary Data from Establishment and Characterization of a Panel of Human Uveal Melanoma Xenografts Derived from Primary and/or Metastatic Tumors
Supplementary Data from Establishment and Characterization of a Panel of Human Uveal Melanoma Xenografts Derived from Primary and/or Metastatic Tumors Open
Supplementary Data from Establishment and Characterization of a Panel of Human Uveal Melanoma Xenografts Derived from Primary and/or Metastatic Tumors
View article: Data from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients
Data from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients Open
A high percentage of uveal melanoma patients develop metastatic tumors predominantly in the liver. We studied the molecular profiles derived from gene expression microarrays and comparative genomic hybridization microarrays, to identify ge…
View article: Supplementary Video 3 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients
Supplementary Video 3 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients Open
Supplementary Video 3 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients
View article: Supplementary Video 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients
Supplementary Video 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients Open
Supplementary Video 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients
View article: Supplementary Video 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients
Supplementary Video 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients Open
Supplementary Video 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients
View article: Supplementary Video 2 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients
Supplementary Video 2 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients Open
Supplementary Video 2 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients
View article: Supplementary Figure 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients
Supplementary Figure 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients Open
Supplementary Figure 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients
View article: Supplementary Table 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients
Supplementary Table 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients Open
Supplementary Table 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients
View article: Supplementary Table 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients
Supplementary Table 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients Open
Supplementary Table 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients
View article: Supplementary Video 3 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients
Supplementary Video 3 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients Open
Supplementary Video 3 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients
View article: Supplementary Video 2 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients
Supplementary Video 2 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients Open
Supplementary Video 2 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients
View article: Supplementary Figure 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients
Supplementary Figure 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients Open
Supplementary Figure 1 from High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients