C. E. Burns-Lynch
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View article: A novel application of the Staudinger ligation to access neutral cyclic di-nucleotide analog precursors via a divergent method
A novel application of the Staudinger ligation to access neutral cyclic di-nucleotide analog precursors via a divergent method Open
Herein we present a scalable and divergent synthesis of cyclic di-nucleotide analog precursors facilitated by differentiated di-amino sugars and a Staudinger ligation to provide medium-sized macrocycles featuring carbamate or urea linkages.