Explanipedia

Donor-derived cell-free DNA and miRNA monitoring for the early prediction and diagnosis of liver allograft rejection and patient outcomes Open

J.A. Julian, Olga Millán, Esther Titos, Pablo Ruíz, Yiliam Fundora , et al. · 2025

Introduction The identification of noninvasive biomarkers for monitoring liver transplant (LT) recipients is crucial for the early detection of graft dysfunction and rejection. Donor-derived cell-free DNA (dd-cfDNA) and microRNAs (miRNAs) …

The Brescia internationally validated European guidelines on minimally invasive liver surgery Open

Mohammad Abu Hilal, Tijs J. Hoogteijling, Bjørn Edwin, Ibrahim Dagher, Mathieu D’Hondt , et al. · 2025

Regional variations and trends in liver transplantation practices across Europe Open

Tommaso Di Maira, Valérie Cailliez, Beatriz Domínguez‐Gil, Beatriz Mahíllo, Marina Álvarez Benito , et al. · 2025

Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis Open

Josepmaria Argemí, María U. Latasa, Stephen R. Atkinson, Ilya O. Blokhin, Veronica Massey , et al. · 2025

Author Correction: Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis Open

Josepmaria Argemí, María U. Latasa, Stephen R. Atkinson, Ilya O. Blokhin, Veronica Massey , et al. · 2025

Machine Learning Algorithms in Controlled Donation After Circulatory Death Under Normothermic Regional Perfusion: A Graft Survival Prediction Model Open

Rafael Calleja, Marcos Rivera, David Guijo-Rubio, Amelia J. Hessheimer, Gloria de la Rosa , et al. · 2025

Background. Several scores have been developed to stratify the risk of graft loss in controlled donation after circulatory death (cDCD). However, their performance is unsatisfactory in the Spanish population, where most cDCD livers are rec…

Intraoperative liquid biopsy as a tool for detecting R1 resection during pancreatoduodenectomy in patients with pancreatic carcinoma: the CETUPANC trial (part II) Open

Javier Padillo–Ruiz, Carlos Martín García, G. Suárez Artacho, Gerardo Blanco‐Fernández, Luis Muñoz‐Bellvís , et al. · 2024

Introduction: A positive surgical margin (R1 resection) is a relevant risk factor for local recurrence in patients with pancreatic ductal adenocarcinoma of the pancreas (PDAC). An intraoperative liquid biopsy (ILB) based on tumor cell mobi…

Effects of the superior mesenteric artery approach <i>versus</i> the no-touch approach during pancreatoduodenectomy on the mobilization of circulating tumour cells and clusters in pancreatic cancer (CETUPANC): randomized clinical trial Open

Javier Padillo–Ruiz, Cristóbal Fresno, G. Suárez, Gerardo Blanco‐Fernández, Luis Muñoz‐Bellvís , et al. · 2024

Background Patients with pancreatic ductal adenocarcinoma present early postoperative systemic metastases, despite complete oncological resection. The aim of this study was to assess two pancreatoduodenectomy approaches with regard to intr…

Defining Global Benchmarks for Laparoscopic Right Posterior Sectionectomy/H67 Open

Jianping Zhao, Yuanxiang Lu, Wanguang Zhang, Darren W. Chua, Qu Liu , et al. · 2024

Objective: We aimed to establish global benchmark outcomes indicators for L-RPS/H67. Background: Minimally invasive liver resections has seen an increase in uptake in recent years. Over time, challenging procedures as laparoscopic right po…

A HYBRID APPROACH TO ABDOMINAL WALL REPAIR IN M2-3W2 HERNIA WITH CROHN´S HISTORY Open

E Gutiérrez, J Guevara-Martínez, Cristina Zapata, R Abad, Constantino Fondevila , et al. · 2024

Objective This presentation aims to showcase the case of a 68-year-old male with fistulizing Crohn's disease and a history of two prior surgeries involving ileocecal resection and resection of enterocutaneous fistulas. The main objective i…

PERITONEAL FLAP CREATION FOR INCISIONAL HERNIA REPAIR VIA eTEP Open

John Martínez, Carlos Alberto Zapata, E Gutiérrez, R Abad, L Asencio , et al. · 2024

Background Peritoneal flaps assist in achieving abdominal wall closure, eliminating the need for mesh bridging and component separation techniques such as the endoscopic transverse abdominis release (eTAR). While maintaining the same conce…

UTILITY OF THE CARBONELL´S RULE IN eTEP VENTRAL HERNIA REPAIR: A MULTICENTER RETROSPECTIVE STUDY Open

S Salido, J Guevara-Martínez, E. Gutiérrez, Carlos Alberto Zapata, Francisco Reinoso‐Barbero , et al. · 2024

Objectives The study aimed to assess the applicability of the Carbonell rule as a predictive tool for the need of component separation (TAR) in extended totally extraperitoneal access (eTEP) ventral hernia repair. Materials and Methods A m…

IS MINIMALLY INVASIVE HERNIA REPAIR SAFE IN PATIENTS WITH PREVIOUS PROSTATE SURGERY? Open

Ravan Moret, S Salido, Carlos Alberto Zapata, E. Gutiérrez, Annalee Mora , et al. · 2024

Aim Laparoscopic inguinal hernia repair after previous radical prostatectomy is considered complex due to the subsequent preperitoneal fibrotic reaction. For this reason, it has been considered a contraindication, and many surgeons have op…

SURGICAL MANAGEMENT OF W3 INCISIONAL HERNIAS: EVALUATING THE SUCCESS OF ETEP APPROACH Open

S Salido, J Guevara-Martínez, E Gutiérrez, Carlos Alberto Zapata, Francisco Reinoso‐Barbero , et al. · 2024

Aim Treatment of incisional hernias using the extended totally extraperitoneal (eTEP) approach presents significant technical demands. Mostly eTEP is used for W1 and W2 defects due to the challenges posed by larger defects. This study eval…

COMPARATIVE ANALYSIS OF PERITONEAL FLAPS (PF) AND ENDOSCOPIC TRANSVERSUS ABDOMINIS RELEASE (eTAR) FOR MIDLINE RESTORATION IN eTEP INCISIONAL HERNIA REPAIR Open

John Martínez, E Gutiérrez, Cristina Zapata, Ricardo Díaz Abad, M del Mar Olmedo , et al. · 2024

Aim This study aims to compare the utilization of peritoneal flaps (PF) with endoscopic transversus abdominis release (eTAR) for midline restoration in incisional hernia repair via the enhanced-view totally extraperitoneal (eTEP) approach.…

EVOLUTION OF THE eTEP TECHNIQUE FOR VENTRAL HERNIA REPAIR: SIX-YEAR SINGLE-SURGEON EXPERIENCE WITH TECHNICAL ADVANCEMENTS AND ADAPTATIONS Open

S Salido, J Guevara-Martínez, Carlos Alberto Zapata, E. Gutiérrez, Francisco Reinoso‐Barbero , et al. · 2024

Objective The aim of this study was to assess the learning curve and the implementation of tools for the correction of ventral hernias using the extended totally extraperitoneal (eTEP) approach. Materials and Methods All patients underwent…

Impact of neoadjuvant chemotherapy on short-term outcomes after simple and complex minimally invasive minor hepatectomy for colorectal liver metastases: A propensity-score matched and coarsened exact matched study Open

Tijs J. Hoogteijling, Mohammad Abu Hilal, Giuseppe Zimmitti, Davit L. Aghayan, Andrew G. R. Wu , et al. · 2024

European Society for Organ Transplantation (ESOT) Consensus Statement on Outcome Measures in Liver Transplantation According to Value-Based Health Care Open

Marco Carbone, James Neuberger, Ian Rowe, Wojciech G. Polak, Anna Forsberg , et al. · 2024

Liver transplantation is a highly complex, life-saving, treatment for many patients with advanced liver disease. Liver transplantation requires multidisciplinary teams, system-wide adaptations and significant investment, as well as being a…

ANORECTAL ULCERS DIFFERENTIAL DIAGNOSIS FOR GENERAL SURGEONS Open

Francisco J Reinoso-Lozano, Mario Álvarez Gallego, Elena Sendagorta Cudós, Sara Gortázar de las Casas, M.B. Alonso-Bartolomé , et al. · 2023

Introducción. La patología perianal es frecuente entre la población de hombres que tienen sexo con hombres (HSH). A menudo se manifiesta en forma de úlceras anorrectales, cuyo diagnóstico diferencial es amplio y debe ser conocido para el c…

Impact of liver cirrhosis, severity of cirrhosis and portal hypertension on the difficulty of laparoscopic and robotic minor liver resections for primary liver malignancies in the anterolateral segments Open

Junhao Zheng, Xiao Liang, Andrew G. R. Wu, Tousif Kabir, Olivier Scatton , et al. · 2023

Cyclosporine vs. tacrolimus after liver transplantation for primary sclerosing cholangitis – a propensity score-matched intention-to-treat analysis Open

Fredrik Åberg, Ville Sallinen, Samuli Tuominen, René Adam, Vincent Karam , et al. · 2023

The optimal calcineurin inhibitor to use after liver transplantation in patients with primary sclerosing cholangitis has yet to be firmly established. Since randomized trials with long follow-up are unlikely to be performed, multicontinent…

European Society of Organ Transplantation (ESOT) Consensus Report on Downstaging, Bridging and Immunotherapy in Liver Transplantation for Hepatocellular Carcinoma Open

Marco P. A. W. Claasen, Dimitri Sneiders, Yannick S. Rakké, René Adam, Sherrie Bhoori , et al. · 2023

Liver transplantation offers the best chance of cure for most patients with non-metastatic hepatocellular carcinoma (HCC). Although not all patients with HCC are eligible for liver transplantation at diagnosis, some can be downstaged using…

#730 Hepatic hilium cytoreductive surgery for ovarian cancer relapse Open

Myriam Gracia, Constantino Fondevila, Alicia Hernández, I. Prieto, Ignacio Zapardiel · 2023

Introduction/Background Ovarian cancer relapse is a challenge situation, that requires the evaluation of many clinical aspects with a multidisciplinary approach. A recent randomized trial showed that cytoreductive surgery followed by chemo…

E-AHPBA–ESSO–ESSR Innsbruck consensus guidelines for preoperative liver function assessment before hepatectomy Open

Florian Primavesi, Manuel Maglione, Federica Cipriani, Timm Denecke, Christian E. Oberkofler , et al. · 2023

Background Posthepatectomy liver failure (PHLF) contributes significantly to morbidity and mortality after liver surgery. Standardized assessment of preoperative liver function is crucial to identify patients at risk. These European consen…

Impact of liver cirrhosis and portal hypertension on minimally invasive limited liver resection for primary liver malignancies in the posterosuperior segments: An international multicenter study Open

Chétana Lim, Olivier Scatton, Andrew G. R. Wu, Wanguang Zhang, Kiyoshi Hasegawa , et al. · 2023

Propensity Score-Matching Analysis Comparing Robotic Versus Laparoscopic Limited Liver Resections of the Posterosuperior Segments Open

Felix Krenzien, Moritz Schmelzle, Johann Pratschke, Linda Feldbrügge, Rong Liu , et al. · 2023

Objective: The purpose of this study was to compare the outcomes of robotic limited liver resections (RLLR) versus laparoscopic limited liver resections (LLLR) of the posterosuperior segments. Background: Both laparoscopic and robotic live…

The multi-societal European consensus on the terminology, diagnosis and management of patients with synchronous colorectal cancer and liver metastases: an E-AHPBA consensus in partnership with ESSO, ESCP, ESGAR, and CIRSE Open

Ajith K. Siriwardena, Alejandro Serrablo, Åsmund Avdem Fretland, Stephen J. Wigmore, José Manuel Ramia , et al. · 2023

RNF41 orchestrates macrophage-driven fibrosis resolution and hepatic regeneration Open

Alazne Moreno-Lanceta, Mireia Medrano-Bosch, Yiliam Fundora, Meritxell Perramón, Jessica Aspas , et al. · 2023

Hepatic inflammation is a common trigger of chronic liver disease. Macrophage activation is a predictive parameter for survival in patients with cirrhosis. Ring finger protein 41 (RNF41) negatively regulates proinflammatory cytokines and r…

Reply to: “Reconstruction for complex portal vein thrombosis – Anatomical if possible” Open

Yiliam Fundora, Amelia J. Hessheimer, Constantino Fondevila · 2023

Impact of liver cirrhosis, the severity of cirrhosis, and portal hypertension on the outcomes of minimally invasive left lateral sectionectomies for primary liver malignancies Open

Fabrício Ferreira Coelho, Paulo Herman, Jaime Arthur Pirola Krüger, Andrew G. R. Wu, Ken Min Chin , et al. · 2023

Constantino Fondevila YOU? Author Swipe