C. Ghander
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Can back-wall cystic figures of thyroid nodules predict benignity? Open
Background According to the European Thyroid Association (ETA) 2023 consensus, hyperechoic spots correspond to different subtypes: comet tail artifacts, back-wall cystic figures (BWCF), and microcalcifications. BWCF are supposed to be in f…
Update on interventional techniques for thyroid and parathyroid pathologies Open
Over the past two decades, interventional techniques in cervical endocrine pathology have evolved significantly, offering less invasive alternatives to conventional surgery. This update reviews the latest advances in non-surgical approache…
An update on management of cytologically indeterminate thyroid nodules Open
Thyroid nodules are common, but only 5-15% are cancerous. Fine-needle aspiration cytology is the gold-standard examination for determining the nature of a thyroid nodule, with results reported according to the Bethesda International Classi…
View article: Natural history of medullary thyroid carcinoma in MEN 2 patients carrying a variant at codon 804 in the RET proto-oncogene: A study by the French Neuroendocrine Tumor Group (GTE)
Natural history of medullary thyroid carcinoma in MEN 2 patients carrying a variant at codon 804 in the RET proto-oncogene: A study by the French Neuroendocrine Tumor Group (GTE) Open
The RET pathogenic variants affecting the codon 804 mainly led to low aggressiveness disease, with late presentation and prolonged DFS. We suggest surgery in relatives if calcitonin values are above 6ng/L, instead of 10ng/L. Long-term surv…
View article: Chapter 10: What parathyroid imaging is required for hyperparathyroidism?
Chapter 10: What parathyroid imaging is required for hyperparathyroidism? Open
In over 80% of cases, primary hyperparathyroidism results from hypersecretion of PTH by a single parathyroid adenoma. Multi-glandular involvement, combining adenoma and/or hyperplasia in varying proportions, is also possible, although less…
View article: Performance of the AmpliSeq NGS panel in thyroid nodules with indeterminate cytology
Performance of the AmpliSeq NGS panel in thyroid nodules with indeterminate cytology Open
Objective Fine-needle aspiration (FNA) cytological analysis fails to confirm the benignity or malignancy of Bethesda III, IV and V thyroid nodules. Molecular tests performed on FNA samples have demonstrated interesting results in improving…
View article: Learning curve for radiofrequency ablation of benign thyroid nodules
Learning curve for radiofrequency ablation of benign thyroid nodules Open
Objective: To evaluate the effect of operator experience on the treatment outcomes of radiofrequency ablation (RFA) for benign thyroid nodules (BTN). Methods: Data from the 90 first RFA procedures of a single operator in treating benign th…
View article: Therapeutic Plasma Exchange in Refractory Hyperthyroidism
Therapeutic Plasma Exchange in Refractory Hyperthyroidism Open
TPE allowed a safe decrease of 50% in thyroid hormone levels, and it should be considered for refractory hyperthyroid patients when medical treatments are contraindicated or have failed to restore euthyroidism, irrespective of the etiology…
View article: Supplementary Material for: Therapeutic Plasma Exchange in Refractory Hyperthyroidism
Supplementary Material for: Therapeutic Plasma Exchange in Refractory Hyperthyroidism Open
Introduction: Hyperthyroid patients who are unresponsive to medical treatment remain a challenging clinical problem. Objective: The goal of our study was to evaluate the use of therapeutic plasma exchange (TPE) in hyperthyroid patients and…