Corinna Helmle‐Kolb
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View article: Bimodal Acute Effects of A1 Adenosine Receptor Activation on Na+/H+ Exchanger 3 in Opossum Kidney Cells
Bimodal Acute Effects of A1 Adenosine Receptor Activation on Na+/H+ Exchanger 3 in Opossum Kidney Cells Open
Regulation of renal apical Na+/H+ exchanger 3 (NHE3) activity by adenosine has been suggested to contribute to acute control of mammalian Na(+) homeostasis. The mechanism by which adenosine controls NHE3 activity in a renal cell line was e…
View article: A4 Organic solutes/Osmolytes/ Renal metabolism (M12 - M30)
A4 Organic solutes/Osmolytes/ Renal metabolism (M12 - M30) Open
We previously showed that acute A 1 adenosine receptor activation by CPA (N 6 -cyclopentidyladenosine) inactivates NHE3 via the PLC/Ca 2+ /PKC signaling pathway.The purpose of the present study was to examine the underlying molecular mecha…
View article: Molecular aspects of acute inhibition of Na<sup>+</sup>‐H<sup>+</sup> exchanger NHE3 by A<sub>2</sub>‐adenosine receptor agonists
Molecular aspects of acute inhibition of Na<sup>+</sup>‐H<sup>+</sup> exchanger NHE3 by A<sub>2</sub>‐adenosine receptor agonists Open
Adenosine regulates Na + homeostasis by its acute effects on renal Na + transport. We have shown in heterologously transfected A6/C1 cells (renal cell line from Xenopus laevis ) that adenosine‐induced natriuresis may be effected partly via…
View article: Adenosine inhibits the transfected Na<sup>+</sup>‐H<sup>+</sup> exchanger NHE3 in <i>Xenopus laevis</i> renal epithelial cells (A6/C1)
Adenosine inhibits the transfected Na<sup>+</sup>‐H<sup>+</sup> exchanger NHE3 in <i>Xenopus laevis</i> renal epithelial cells (A6/C1) Open
1. Adenosine influences the vectorial transport of Na+ and HCO3- across kidney epithelial cells. However, its action on effector proteins, such as the Na+-H+ exchanger NHE3, an epithelial brush border isoform of the Na+-H+ exchanger (NHE) …