Francesco Izzo
YOU?
Author Swipe
View article: Cross-Software Radiomic Feature Robustness Assessed by Hierarchical Clustering and Composite Index Analysis: A Multi-Cancer Study on Colorectal and Liver Lesions
Cross-Software Radiomic Feature Robustness Assessed by Hierarchical Clustering and Composite Index Analysis: A Multi-Cancer Study on Colorectal and Liver Lesions Open
Background: Radiomic feature robustness is a key prerequisite for the reproducibility and clinical translation of imaging biomarkers. Variability across software platforms can significantly affect feature consistency, compromising predicti…
View article: LIVERATION trial: a multicentre European randomised study on radiofrequency margin coagulation and its impact on oncological outcomes after liver surgery – study protocol
LIVERATION trial: a multicentre European randomised study on radiofrequency margin coagulation and its impact on oncological outcomes after liver surgery – study protocol Open
Introduction Surgical margins are crucial in determining postoperative local recurrence (LR) in patients with colorectal liver metastasis (CRLM) and hepatocellular carcinoma (HCC). Achieving a margin greater than 1 cm can be challenging du…
View article: Genetic, Epidemiological, Clinical, and Therapeutic Trajectories in Colon and Rectal Cancers
Genetic, Epidemiological, Clinical, and Therapeutic Trajectories in Colon and Rectal Cancers Open
Colorectal cancer (CRC) is among the most prevalent malignancies worldwide, representing the second leading cause of cancer-related mortality and accounting for approximately 2 million new cases and nearly half a million deaths annually. G…
View article: MRI management of focal liver lesions: what a beginner cannot fail to know
MRI management of focal liver lesions: what a beginner cannot fail to know Open
Magnetic resonance imaging (MRI) is currently recognized as the most suitable diagnostic tool for the detection and characterization of focal liver lesions. The combination of morphological and functional data allows, in different clinical…
View article: The Study of Chromobox Protein Homolog 4 in 3D Organoid Models of Colon Cancer as a Potential Predictive Marker
The Study of Chromobox Protein Homolog 4 in 3D Organoid Models of Colon Cancer as a Potential Predictive Marker Open
The Chromobox (CBX) family comprises key epigenetic regulators involved in transcriptional repression through chromatin modifications. Dysregulation of polycomb CBX proteins has been linked to epigenetic gene silencing and cancer progressi…
View article: Adequate lymphadenectomy and adjuvant capecitabine warrant survival benefit in gallbladder cancer
Adequate lymphadenectomy and adjuvant capecitabine warrant survival benefit in gallbladder cancer Open
A significant proportion of patients still did not receive adequate lymphadenectomy and aCTx. Patients treated according to contemporary surgical oncology principles presented a survival benefit. These principles should be further evaluate…
View article: Visual Perception and Pre-Attentive Attributes in Oncological Data Visualisation
Visual Perception and Pre-Attentive Attributes in Oncological Data Visualisation Open
In the era of precision medicine, effective data visualisation plays a pivotal role in supporting clinical decision-making by translating complex, multidimensional datasets into intuitive and actionable insights. This paper explores the fo…
View article: Robotic Liver Resection for Breast Cancer Metastasis: A Multicenter Case Series and Literature Review
Robotic Liver Resection for Breast Cancer Metastasis: A Multicenter Case Series and Literature Review Open
Background: Breast cancer is a widespread disease and, when metastatic, has a bleak prognosis. The surgical approach for BCLM has had a limited role, but robotic surgery could find an important place. Methods: Data were collected from a mu…
View article: An Update of AI and Radiomics in Precision Oncology: Insights from Liver Tumors as Case Models
An Update of AI and Radiomics in Precision Oncology: Insights from Liver Tumors as Case Models Open
The integration of digital health technologies, open-access data, and artificial intelligence (AI) is reshaping oncology by enabling more precise and personalized care. This review provides a focused update on AI, radiomics, and data integ…
View article: Treatments and cancer: implications for radiologists
Treatments and cancer: implications for radiologists Open
This review highlights the critical role of radiologists in personalized cancer treatment, focusing on the evaluation of treatment outcomes using imaging tools like Computed Tomography (CT), Magnetic Resonance Imaging (MRI), and Ultrasound…
View article: Robotic Liver Resection for Hepatocellular Carcinoma: A Multicenter Case Series
Robotic Liver Resection for Hepatocellular Carcinoma: A Multicenter Case Series Open
Background: Liver resection is the standard treatment for resectable hepatocellular carcinoma (HCC). The advent of robotic surgery has extended its application in liver surgery, reducing post-operative complications without compromising on…
View article: Clinical and genetic drivers of oligo-metastatic disease in colon cancer
Clinical and genetic drivers of oligo-metastatic disease in colon cancer Open
OMD, characterized by male predominance, single-site involvement, and distinct molecular features in colon cancer, suggests the need for tailored management strategies.
View article: Intermittent or Continuous Panitumumab Plus Fluorouracil, Leucovorin, and Irinotecan for First-Line Treatment of <i>RAS</i> and <i>BRAF</i> Wild-Type Metastatic Colorectal Cancer: The IMPROVE Trial
Intermittent or Continuous Panitumumab Plus Fluorouracil, Leucovorin, and Irinotecan for First-Line Treatment of <i>RAS</i> and <i>BRAF</i> Wild-Type Metastatic Colorectal Cancer: The IMPROVE Trial Open
PURPOSE To investigate whether intermittent treatment after an induction phase of first-line schedule of fluorouracil, leucovorin, and irinotecan (FOLFIRI) plus panitumumab (PAN) prevents or delays the onset of resistance and improves safe…
View article: Is robotic liver resection feasible in patients with lesions in close proximity to major vessels? A propensity score matching analysis
Is robotic liver resection feasible in patients with lesions in close proximity to major vessels? A propensity score matching analysis Open
The presents study shows how robotic surgery is a valid and safe technique also for resection of tumors close to vascular pedicles.
View article: Caritas’s Work for the Goals of Agenda 2030: A Study on the Services Provided in Campania
Caritas’s Work for the Goals of Agenda 2030: A Study on the Services Provided in Campania Open
The United Nations’ Agenda 2030 has established a series of Sustainable Development Goals to address global challenges, including poverty, food insecurity, access to education, and social inequality. In this context, charitable organizatio…
View article: Disability and marketing: a bibliometric analysis and systematic literature review
Disability and marketing: a bibliometric analysis and systematic literature review Open
The needs of people with disabilities have been largely overlooked in the marketplace and in the development and promotion of products and services. As the marketing system has the potential to drive changes in the education system, indust…
View article: Caritas for the Goals of the Agenda 2030: A Study on the Services Provided in Campania
Caritas for the Goals of the Agenda 2030: A Study on the Services Provided in Campania Open
The United Nations’ Agenda 2030 has established a series of Sustainable Development Goals to address global challenges, including poverty, food insecurity, access to education, and social inequality. In this context, charitable organizatio…
View article: Robotic Major Hepatectomy in Elderly Patient
Robotic Major Hepatectomy in Elderly Patient Open
Background: the role of minimally invasive liver surgery has been progressively developed, with the practice increasing in safety and feasibility also with respect to major liver resections. The aim of this study was to analyze the feasibi…
View article: Pancreatic Neuroendocrine Tumors: What Is the Best Surgical Option?
Pancreatic Neuroendocrine Tumors: What Is the Best Surgical Option? Open
Background: Pancreatic neuroendocrine tumors (pNETs) represent a rare subset of pancreatic cancer. Functional tumors cause hormonal changes and clinical syndromes, while non-functional ones are often diagnosed late. Surgical management nee…
View article: Intraperitoneal prophylactic drain after pancreaticoduodenectomy: an Italian survey
Intraperitoneal prophylactic drain after pancreaticoduodenectomy: an Italian survey Open
Intraperitoneal prophylactic drain (IPD) use in pancreaticoduodenectomy (PD) is still controversial. A survey was designed to investigate surgeons’ use of IPD in PD patients through 23 questions and one clinical vignette. For the clinical …
View article: Pancreatic Neuroendocrine Tumors: What Is the Best Surgical Option?
Pancreatic Neuroendocrine Tumors: What Is the Best Surgical Option? Open
Background: Pancreatic neuroendocrine tumors (pNETs) represents a rare subset of pancreatic cancer. Functional tumors caused hormonal changes and clinical syndromes, while non-functional ones are often diagnosed late. Surgical management n…
View article: FRUCTOSE EXACERBATES ANTHRACYCLINE AND HER–2 BLOCKING AGENT MEDIATED CARDIOTOXICITY THROUGH NLRP3 AND MYD88 MEDIATED PATHWAYS: NEW ROLES OF SWEETENERS IN CARDIO–ONCOLOGY
FRUCTOSE EXACERBATES ANTHRACYCLINE AND HER–2 BLOCKING AGENT MEDIATED CARDIOTOXICITY THROUGH NLRP3 AND MYD88 MEDIATED PATHWAYS: NEW ROLES OF SWEETENERS IN CARDIO–ONCOLOGY Open
Background Combinatorial therapy based on anthracyclines and HER–2 blocking agents increases the risk of cardiomyopathy in women with breast cancer. Fructose is a monosaccharide associated with high risk of diabetes, non–alcoholic fatty li…
View article: SOLUBLE GUANYLATE CYCLASE ACTIVATOR VERICIGUAT PREVENTS ANTHRACYCLINE–MEDIATED CARDIOTOXICITY AND SARCOPENIA THROUGH NO–SGC–CGMP–NLRP3 PATHWAY: POTENTIAL APPLICATION IN CANCER PATIENTS
SOLUBLE GUANYLATE CYCLASE ACTIVATOR VERICIGUAT PREVENTS ANTHRACYCLINE–MEDIATED CARDIOTOXICITY AND SARCOPENIA THROUGH NO–SGC–CGMP–NLRP3 PATHWAY: POTENTIAL APPLICATION IN CANCER PATIENTS Open
Background Anthracycline–induced cardiomyopathies and sarcopenia are frequently seen in cancer patients, affecting their overall survival and quality of life; therefore, new cardioprotective strategies are needed in cardioncology. Vericigu…