Christoph Krafft
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View article: Chiral SURMOFs for Vibrational Circular Dichroism: Multiscale Modeling and Experimental Insights
Chiral SURMOFs for Vibrational Circular Dichroism: Multiscale Modeling and Experimental Insights Open
Chiral surface‐anchored metal‐organic frameworks (SURMOFs) are emerging as versatile platforms for enantioselective separation, sensing, and the manipulation of circularly polarized light. To harness their full potential, predictive modeli…
View article: Nanochemical Cell-Surface Evaluation in Photothermal Spectroscopic Imaging of Antimicrobial Interactions in the Model System <i>Bacillus subtilis</i> and Vancomycin
Nanochemical Cell-Surface Evaluation in Photothermal Spectroscopic Imaging of Antimicrobial Interactions in the Model System <i>Bacillus subtilis</i> and Vancomycin Open
The power of photothermal spectroscopic imaging to visualize antimicrobial interactions on the surfaces of individual bacteria cells has been demonstrated on the model system Bacillus subtilis and vancomycin using mid-infrared photo…
View article: Rapid Microplastic Detection Using High-Throughput Screening Raman Spectroscopy
Rapid Microplastic Detection Using High-Throughput Screening Raman Spectroscopy Open
Microplastic pollution poses a significant environmental challenge, with particles ranging from micrometers to millimeters contaminating ecosystems worldwide. Traditional Raman microspectroscopy struggles to balance spatial resolution, fie…
View article: Mid-infrared photo-induced force microscopy (PiF-IR) on model system Bacillus subtilis - vancomycin
Mid-infrared photo-induced force microscopy (PiF-IR) on model system Bacillus subtilis - vancomycin Open
This data set contains raw data used for the manuscript: Title: Nanochemical cell-surface evaluation in photothermal spectroscopic imaging of antimicrobial interactions in model system Bacillus subtilis and vancomycin Authors: Maryam Ali,a…
View article: Interlaboratory Comparison Reveals State of the Art in Microplastic Detection and Quantification Methods
Interlaboratory Comparison Reveals State of the Art in Microplastic Detection and Quantification Methods Open
In this study, we investigate the current accuracy of widely used microplastic (MP) detection methods through an interlaboratory comparison (ILC) involving ISO-approved techniques. The ILC was organized under the prestandardization platfor…
View article: Deficiency in The Actin Nucleator Cordon Bleu (Cobl) Causes Hypoplastic Enamel in Murine Mandibular Molars
Deficiency in The Actin Nucleator Cordon Bleu (Cobl) Causes Hypoplastic Enamel in Murine Mandibular Molars Open
View article: Design of a Dispersive 1064 nm Fiber Probe Raman Imaging Spectrometer and Its Application to Human Bladder Resectates
Design of a Dispersive 1064 nm Fiber Probe Raman Imaging Spectrometer and Its Application to Human Bladder Resectates Open
This study introduces a compact Raman spectrometer with a 1064 nm excitation laser coupled with a fiber probe and an inexpensive motorized stage, offering a promising alternative to widely used Raman imaging instruments with 785 nm excitat…
View article: Design of a Dispersive 1064 nm Fiber Probe Raman Imaging Spectrometer and Its Application to Human Bladder Resectates
Design of a Dispersive 1064 nm Fiber Probe Raman Imaging Spectrometer and Its Application to Human Bladder Resectates Open
This study introduces a compact Raman spectrometer with a 1064 nm excitation laser coupled with a fiber probe and an inexpensive motorized stage, offering a promising alternative to widely used Raman imaging instruments with 785 nm excitat…
View article: Physics for health
Physics for health Open
Chapter 5 presents an introduction and sections on: accelerators for health; bionics and robotics; physics for health science; physics research against pandemics; further diagnostics and therapies.
View article: Advancing cerumen analysis: exploring innovative vibrational spectroscopy techniques with respect to their potential as new point-of-care diagnostic tools
Advancing cerumen analysis: exploring innovative vibrational spectroscopy techniques with respect to their potential as new point-of-care diagnostic tools Open
The study demonstrates the potential of advanced vibrational spectroscopy to reveal the complex molecular composition of cerumen, suggesting its promising application as a non-invasive diagnostic tool for identifying disease-related biomar…
View article: Nanoscale chemical characterization of secondary protein structure of F-Actin using mid-infrared photoinduced force microscopy (PiF-IR)
Nanoscale chemical characterization of secondary protein structure of F-Actin using mid-infrared photoinduced force microscopy (PiF-IR) Open
The recently developed photoinduced force microscopy for mid-infrared (PiF-IR) offers high spectral resolution in combination with surface sensitivity and a spatial resolution in the range of a few nanometers. Although PiF-IR has primarily…
View article: Investigating biochemical and structural changes of glycated collagen using multimodal multiphoton imaging, Raman spectroscopy, and atomic force microscopy
Investigating biochemical and structural changes of glycated collagen using multimodal multiphoton imaging, Raman spectroscopy, and atomic force microscopy Open
Advanced glycation end products (AGEs) form extracellular crosslinking with collagenous proteins, which contributes to the development of diabetic complications. In this study, AGEs-related pentosidine (PENT) crosslinks-induced structural …
View article: Issue Information
Issue Information Open
View article: Raman Spectroscopic Imaging of Human Bladder Resectates towards Intraoperative Cancer Assessment
Raman Spectroscopic Imaging of Human Bladder Resectates towards Intraoperative Cancer Assessment Open
Raman spectroscopy offers label-free assessment of bladder tissue for in vivo and ex vivo intraoperative applications. In a retrospective study, control and cancer specimens were prepared from ten human bladder resectates. Raman microspect…
View article: Nanoscale chemical characterization of secondary protein structure of F-Actin using mid-infrared photoinduced force microscopy (PiF-IR)
Nanoscale chemical characterization of secondary protein structure of F-Actin using mid-infrared photoinduced force microscopy (PiF-IR) Open
Raw data for manuscript for special issue in Spectrochimica Acta related to ECSBM 2022
View article: Nanoscale chemical characterization of secondary protein structure of F-Actin using mid-infrared photoinduced force microscopy (PiF-IR)
Nanoscale chemical characterization of secondary protein structure of F-Actin using mid-infrared photoinduced force microscopy (PiF-IR) Open
Raw data for manuscript for special issue in Spectrochimica Acta related to ECSBM 2022
View article: Opportunities of optical and spectral technologies in intraoperative histopathology
Opportunities of optical and spectral technologies in intraoperative histopathology Open
Modern optical and spectral technologies represent powerful approaches for a molecular characterization of tissues enabling delineating pathological tissues but also a label-free grading and staging of tumors in terms of computer-assisted …
View article: Microplastic identification using Raman microsocpy
Microplastic identification using Raman microsocpy Open
The manufacturing of plastics has expanded enormously over the previous half-century. Degradation of plastic leads to microplastics (MP's) which appear to have become increasingly common in the environment. They have been found almost ever…
View article: Optical Photothermal Infrared Spectroscopy – a new reference method for microplastic identification
Optical Photothermal Infrared Spectroscopy – a new reference method for microplastic identification Open
Material identification is key to assessing the concentration and abundance of microplastic particles in a sample. So far, which method is best suited to probe microplastic particles is still under debate. In 2016 Käppler et al. (Anal Bioa…
View article: Optical photothermal infrared spectroscopy with simultaneously acquired Raman spectroscopy for two-dimensional microplastic identification
Optical photothermal infrared spectroscopy with simultaneously acquired Raman spectroscopy for two-dimensional microplastic identification Open
In recent years, vibrational spectroscopic techniques based on Fourier transform infrared (FTIR) or Raman microspectroscopy have been suggested to fulfill the unmet need for microplastic particle detection and identification. Inter-system …
View article: Remineralization of Artificially Demineralized Human Enamel and Dentin Samples by Zinc-Carbonate Hydroxyapatite Nanocrystals
Remineralization of Artificially Demineralized Human Enamel and Dentin Samples by Zinc-Carbonate Hydroxyapatite Nanocrystals Open
(1) Background: Decalcified enamel and dentin surfaces can be regenerated with non-fluoride-containing biomimetic systems. This study aimed to investigate the effect of a zinc carbonate-hydroxyapatite-containing dentifrice on artificially …
View article: Two-dimensional Identification of Microplastics: Comparison of Optical Photothermal Infrared Spectroscopy with Fourier-Transform Infrared and Raman Spectroscopy
Two-dimensional Identification of Microplastics: Comparison of Optical Photothermal Infrared Spectroscopy with Fourier-Transform Infrared and Raman Spectroscopy Open
In recent years, vibrational spectroscopic techniques based on Fourier transform infrared (FTIR) or Raman microspectroscopy have been suggested to fulfill the unmet need for microplastic particle detection and identification. Inter-system …
View article: NanIR-PMMA-RawData
NanIR-PMMA-RawData Open
Raw data sets for manuscript "Interference effects in nanoscale infrared spectroscopy methods"
View article: NanIR-PMMA-RawData
NanIR-PMMA-RawData Open
Raw data sets for manuscript "Interference effects in nanoscale infrared spectroscopy methods"
View article: Understanding viruses and viral infections by biophotonic methods
Understanding viruses and viral infections by biophotonic methods Open
In the last few decades outbreaks of viral infections have often challenged the world‐wide health infrastructure and caused a significant financial burden as well as human suffering despite progress in diagnostic technologies. The recent o…
View article: Surface-Enhanced Raman Spectroscopy to Characterize Different Fractions of Extracellular Vesicles from Control and Prostate Cancer Patients
Surface-Enhanced Raman Spectroscopy to Characterize Different Fractions of Extracellular Vesicles from Control and Prostate Cancer Patients Open
Extracellular vesicles (EVs) are membrane-enclosed structures ranging in size from about 60 to 800 nm that are released by the cells into the extracellular space; they have attracted interest as easily available biomarkers for cancer diagn…
View article: Monitoring Changes in Biochemical and Biomechanical Properties of Collagenous Tissues Using Label-Free and Nondestructive Optical Imaging Techniques
Monitoring Changes in Biochemical and Biomechanical Properties of Collagenous Tissues Using Label-Free and Nondestructive Optical Imaging Techniques Open
We demonstrate the ability of nondestructive optical imaging techniques such as second-harmonic generation (SHG), two-photon fluorescence (TPF), fluorescence lifetime imaging (FLIM), and Raman spectroscopy (RS) to monitor biochemical and m…
View article: Assessment of shifted excitation Raman difference spectroscopy in highly fluorescent biological samples
Assessment of shifted excitation Raman difference spectroscopy in highly fluorescent biological samples Open
Common baseline corrections often fail for Raman spectra with high fluorescent background as observed in genipin crosslinked pericardium. An optimized SERDS approach suppresses the background effectively and gives high quality reconstructe…
View article: Comparability of Raman Spectroscopic Configurations: A Large Scale Cross-Laboratory Study
Comparability of Raman Spectroscopic Configurations: A Large Scale Cross-Laboratory Study Open
The variable configuration of Raman spectroscopic platforms is one of the major obstacles in establishing Raman spectroscopy as a valuable physicochemical method within real-world scenarios such as clinical diagnostics. For such real world…
View article: Comparability of Raman Spectroscopic Configurations: A Large Scale Cross-Laboratory Study
Comparability of Raman Spectroscopic Configurations: A Large Scale Cross-Laboratory Study Open
Slightly processed raw data for the paper 'Comparability of Raman Spectroscopic Configurations: A Large Scale Cross-Laboratory Study' The processing include a spike removal to allow an interpolation to a common wavenumber …