Lan Chen
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View article: Evidence of a two-dimensional nitrogen crystalline structure on silver surfaces
Evidence of a two-dimensional nitrogen crystalline structure on silver surfaces Open
Nitrogen, the most abundant element in Earth's atmosphere, exists as a diatomic gas under standard temperature and pressure. In the two-dimensional (2D) limit, atomically thin nitrogen, termed nitrogene, has been theoretically predicted to…
View article: A Bioinspired Force‐Inducible Hydrogel Conduit for Peripheral Nerve Regeneration
A Bioinspired Force‐Inducible Hydrogel Conduit for Peripheral Nerve Regeneration Open
Long‐gap peripheral nerve injury (PNI) presents a significant challenge since the growth cone at the proximal end fails to detect and respond to neurotrophic signals from the distal ends, even when bridging the long‐gap with nerve guide co…
View article: Impaired Cellular Immunity and Cross‐Reactive Humoral Responses to Mpox Virus in HIV‐Infected Individuals Vaccinated with Vaccinia Virus Tiantan Strain
Impaired Cellular Immunity and Cross‐Reactive Humoral Responses to Mpox Virus in HIV‐Infected Individuals Vaccinated with Vaccinia Virus Tiantan Strain Open
In the global response to the current mpox epidemic, understanding immune memory to the vaccinia virus and cross‐immunity to the mpox virus (MPXV) among people living with HIV (PLWH) is critical. Blood samples were collected from PLWH born…
View article: Real-space observation of a time-reversal invariant topological state in twisted bilayer InSe
Real-space observation of a time-reversal invariant topological state in twisted bilayer InSe Open
The moiré superlattice formed by van der Waals (vdW) stacking of two-dimensional (2D) monolayers with a twist angle can give rise to a variety of novel correlated physical phenomena. In this study, we propose that a 2D semiconductor compos…
View article: A study on the clinical effectiveness of a tiered management model for type 2 diabetes based on a three-level linkage mechanism in the context of residency training: a randomized controlled trial
A study on the clinical effectiveness of a tiered management model for type 2 diabetes based on a three-level linkage mechanism in the context of residency training: a randomized controlled trial Open
Background With the widespread implementation of General Practice Residency Training (GPRT) in China, primary care institutions have enhanced chronic disease management capabilities. However, research on tiered management for type 2 diabet…
View article: Stability, accuracy, and clinical performance of enzymatic total CO₂ measurement: Evaluation of the Snibe and Roche assays
Stability, accuracy, and clinical performance of enzymatic total CO₂ measurement: Evaluation of the Snibe and Roche assays Open
Objectives To evaluate the stability, accuracy, and clinical performance of the Snibe CO₂ assay compared with the Roche CO₂ reagent and to investigate factors affecting total CO₂ measurements in different clinical conditions. Methods Total…
View article: Performance evaluation of a novel RapiSafe HIV Ag/Ab combi rapid test for the detection of HIV antigen and antibodies
Performance evaluation of a novel RapiSafe HIV Ag/Ab combi rapid test for the detection of HIV antigen and antibodies Open
Background The detection of acute HIV infection (AHI) is vital for timely diagnosis and appropriate management, thus, in vitro diagnostic tests that accurately identify antigen and anti-bodies separately, have a short seroconversion window…
View article: Sustainable tea plantations: Harnessing chemical-microbial synergy and smart application triangulation for targeted weed control
Sustainable tea plantations: Harnessing chemical-microbial synergy and smart application triangulation for targeted weed control Open
This review systematically examines three critical aspects of weed management in tea plantations: (1) characterizing weed biodiversity and assessing multidimensional threats through taxonomic profiling of invasive species, with particular …
View article: Detection of magnetic monopole in image potential states of topological insulators
Detection of magnetic monopole in image potential states of topological insulators Open
Magnetic monopoles, hypothetical particles behaving as isolated magnetic charges, have long been predicted by theories beyond the standard model but remain elusive in experimental detection. In this study, we demonstrate a novel method to …
View article: Association Analysis of the FTO Gene Polymorphisms with Growth and Carcass Traits of Heying Black Chicken and Tissue Expression Profile
Association Analysis of the FTO Gene Polymorphisms with Growth and Carcass Traits of Heying Black Chicken and Tissue Expression Profile Open
Fat volume and obesity-related genes (e.g., the FTO gene) are important candidate genes affecting energy metabolism. Single nucleotide polymorphisms (SNPs) in the FTO gene are associated with carcass, growth and meat quality traits of pigs…
View article: Development of a 10.8-eV tabletop femtosecond laser with tunable polarization for high-resolution angle-resolved photoemission spectroscopy
Development of a 10.8-eV tabletop femtosecond laser with tunable polarization for high-resolution angle-resolved photoemission spectroscopy Open
The development of extreme ultraviolet sources is critical for advancing angle-resolved photoemission spectroscopy (ARPES), a powerful technique for probing the electronic structure of materials. Here, we report the construction of a table…
View article: UNC0638 inhibits SARS-CoV-2 entry by blocking cathepsin L maturation
UNC0638 inhibits SARS-CoV-2 entry by blocking cathepsin L maturation Open
Since the outbreak of SARS-CoV-2, viral mutations have posed significant challenges in identifying therapeutic targets and developing broad-spectrum antiviral drugs. Post-translational modifications of genes involved in interferon producti…
View article: A Dual‐Programmable Metasurface with Duplex Beam Steering for Full‐Space Terahertz Communications
A Dual‐Programmable Metasurface with Duplex Beam Steering for Full‐Space Terahertz Communications Open
Programmable metasurfaces capable of full‐space terahertz (THz) beam steering offer immense potential for new‐paradigm THz applications. Nonetheless, achieving dual programmability for integrated transmission and reflection (T‐R) modes pos…
View article: PRRG4 Brain-Specific Conditional Knockout Mice Display Autism Spectrum Disorder-Like Behaviors
PRRG4 Brain-Specific Conditional Knockout Mice Display Autism Spectrum Disorder-Like Behaviors Open
Background Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized primarily by social deficits and repetitive behaviors. The mechanisms of ASD are complex and are not yet fully understood, although many ASD risk gene…
View article: A potential XGBoost Diagnostic Score for Staphylococcus aureus bloodstream infection
A potential XGBoost Diagnostic Score for Staphylococcus aureus bloodstream infection Open
Staphylococcus aureus ( S. aureus ) bloodstream infection is often life-threatening, and increasing in incidence. We identified 63 differentially expressed genes (DEGs) in the GSE33341 S. aureus infection samples. Subsequently, intersectin…
View article: Partial normalization of microbiota dysbiosis in condyloma acuminatum patients following treatment
Partial normalization of microbiota dysbiosis in condyloma acuminatum patients following treatment Open
Introduction Condyloma acuminatum (CA) is the most common sexually transmitted disease and the presence of microbiota dysbiosis has been observed to promote the progress of the disease. However, the explicit characteristics of microbiota d…
View article: The Artistic Characteristics of “Yi” in Yushu, Qinghai Province, and Its Application in Teaching
The Artistic Characteristics of “Yi” in Yushu, Qinghai Province, and Its Application in Teaching Open
“Yi” is a folk song and dance with unique characteristics in Yushu, Qinghai Province. This paper reviews the cultural connotation, performance form, and artistic characteristics of “Yi,” and deeply analyzes its melody mode, structural char…
View article: Anisotropic Superconductivity in Bilayer Kagome Borophene
Anisotropic Superconductivity in Bilayer Kagome Borophene Open
The unique electron configuration of boron allows it to form a rich variety of allotropes and exhibits great potential for superconductors. In this work, the superconductivity in bilayer Kagome borophene (BK‐borophene) is investigated by f…
View article: Transcriptomic Analysis of the Negative Effect of Epigallocatechin-3-Gallate from Tea Plant (Camellia sinensis) on Agrobacterium-Mediated Transformation Efficiency
Transcriptomic Analysis of the Negative Effect of Epigallocatechin-3-Gallate from Tea Plant (Camellia sinensis) on Agrobacterium-Mediated Transformation Efficiency Open
Agrobacterium-mediated transformation is a widely used method for plant genetic modification. However, its efficiency in tea plants is notably low, and the underlying molecular mechanisms remain unclear, hindering advancements in the molec…
View article: Flat Bands and Temperature-Driven Phase Transition in Quasi-One-Dimensional Zigzag Chains
Flat Bands and Temperature-Driven Phase Transition in Quasi-One-Dimensional Zigzag Chains Open
Flat-band materials have garnered extensive attention due to their captivating properties associated with strong correlation effects. While flat bands have been discovered in several types of 2D materials, their existence in 1D systems rem…
View article: PLSCR1 suppresses SARS-CoV-2 infection by downregulating cell surface ACE2
PLSCR1 suppresses SARS-CoV-2 infection by downregulating cell surface ACE2 Open
Type I interferons exert their antiviral effects against SARS-CoV-2 by inducing the expression of interferon-stimulated genes (ISGs), including but not limited to LY6E, CH25H, IFITM2/3, and IFIH1. However, the antiviral effect and underlyi…