Explanipedia

Lassa fever outcomes and prognostic factors in Nigeria (LASCOPE): a prospective cohort study Open

Alexandre Duvignaud, Marie Jaspard, Ijeoma Chukwudumebi Etafo, Delphine Gabillard, Béatrice Serra , et al. · 2021

Institut National de la Santé et de la Recherche Médicale, University of Oxford, EU, UK Department for International Development, Wellcome Trust, French Ministry of Foreign Affairs, Agence Nationale de Recherches sur le SIDA et les hépatit…

Impact on disease mortality of clinical, biological, and virological characteristics at hospital admission and overtime in COVID‐19 patients Open

Yazdan Yazdanpanah, Alpha Diallo, Christelle Paul, Noémie Mercier, Soizic Le Mestre , et al. · 2020

Little is known on the association between clinical factors and coronavirus disease 2019 (COVID‐19) more than 15 days after diagnosis. We conducted a multicentric prospective cohort of COVID‐19 hospitalized patients to describe clinical, b…

Long-lasting severe immune dysfunction in Ebola virus disease survivors Open

Aurélie Wiedemann, Emile Foucat, Hakim Hocini, Cécile Lefebvre, Boris P. Hejblum , et al. · 2020

Safety and immunogenicity of the live attenuated intranasal pertussis vaccine BPZE1: a phase 1b, double-blind, randomised, placebo-controlled dose-escalation study Open

Maja Jahnmatz, Laura Richert, Nabil Al‐Tawil, Jann Storsæter, Céline Colin , et al. · 2020

European survey on national harmonization in clinical research Open

Annette Magnin, Valentina Cabral Iversen, Gonzalo Calvo, Beata Čečetková, Ola Dale , et al. · 2020

Background Clinical trials remain key to the development of evidence‐based medical practice. However, they are becoming increasingly complex, mainly in a multinational setting. To address these challenges, the European Union (EU) adopted t…

Lassa fever clinical course and setting a standard of care for future randomized trials: A protocol for a cohort study of Lassa-infected patients in Nigeria (LASCOPE) Open

Alexandre Duvignaud, Marie Jaspard, Ijeoma Chukwudumebi Etafo, Béatrice Serra, Chukwuyem Abejegah , et al. · 2020

The LASCOPE study was registered on ClinicalTrial.gov (NCT03655561).

Feasibility of high-throughput sequencing in clinical routine cancer care: lessons from the cancer pilot project of the France Genomic Medicine 2025 plan Open

Céline Auzanneau, Delphine Bacq, C. Bellera, Hélène Blons, Anne Boland , et al. · 2020

Delayed-onset paraparesis in Lassa fever: A case report Open

Alexandre Duvignaud, Mahamadou Doutchi, Chukwuyem Abejegah, Ijeoma Chukwudumebi Etafo, Marie Jaspard , et al. · 2019

Lassa fever (LF) is an endemic viral hemorrhagic fever in West Africa. Among the serious complications of the disease are neurological manifestations whose spectrum is incompletely known. Here we report the case of a 61-year-old man who de…

Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and hypertension. Open

Morgane Baron, Julie O’Sullivan Maillet, Marlène Huyvaert, Aurélie Dechaume, Raphaël Boutry , et al. · 2019

The G-protein-coupled receptor accessory protein MRAP2 is implicated in energy control in rodents, notably via the melanocortin-4 receptor1. Although some MRAP2 mutations have been described in people with obesity1,2,3, their functional co…

Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and hypertension Open

Morgane Baron, Julie O’Sullivan Maillet, Marlène Huyvaert, Aurélie Dechaume, Raphaël Boutry , et al. · 2019

European survey on national training activities in clinical research Open

Annette Magnin, Valentina Cabral Iversen, G. Calvo, Beata Čečetková, Ola Dale , et al. · 2019

Long-lasting severe immune dysfunction in Ebola virus disease survivors Open

Aurélie Wiedemann, M.Sc. Emile Foucat, Hakim Hocini, Mathilde Lefebvre, Alpha Kabinet Kéita , et al. · 2019

Clinical follow-up of Ebola virus disease (EVD) survivors revealed a persistence of clinical symptoms and higher risk of mortality. Long-term analyses of the immune and inflammatory profiles of EVD survivors are currently lacking. Here, we…

Enrolling study personnel in Ebola vaccine trials: from guidelines to practice in a non-epidemic context Open

Édouard Lhomme, Modet Camara, Augustin Augier, Sylvain Landry Faye, Tienhan Sandrine Dabakuyo‐Yonli , et al. · 2019

Safety and efficacy of the rSh28GST urinary schistosomiasis vaccine: A phase 3 randomized, controlled trial in Senegalese children Open

Gilles Riveau, Anne‐Marie Schacht, Jean‐Pierre Dompnier, Dominique Deplanque, Modou Seck , et al. · 2018

ClinicalTrials.gov NCT 00870649.

Prevention of Ebola virus disease through vaccination: where we are in 2018 Open

Yves Lévy, Clifford Lane, Peter Piot, Abdul Habib Beavogui, Mark Kieh , et al. · 2018

Maternal factors associated with perinatal mortality: the 1000 Days cohort study, rural Niger Open

Anne Thomas, Deo Sibongwere, Maguy Daurès, Benjamin Séri, Nafissa Dan-Bouzoua , et al. · 2018

This abstract corresponds with the following video: https://f1000research.com/videos/7-841 presented at Medecins Sans Frontieres UK Scientific Days: Medical Research 2018. This abstract is part of an F1000Research gateway that includes…

EPMA World Congress: Traditional Forum in Predictive, Preventive and Personalised Medicine for Multi-Professional Consideration and Consolidation Open

Estelle Pujos‐Guillot, Julien Bertrand, Mathieu Rambeau, Mélanie Pétéra, Marion Brandolini-Bunlon , et al. · 2017

Relationship between salivary/pancreatic amylase and body mass index: a systems biology approach Open

Amélie Bonnefond, Loïc Yengo, Aurélie Dechaume, Mickaël Canouil, M. Castelain , et al. · 2017

Associations Between Type 2 Diabetes-Related Genetic Scores and Metabolic Traits, in Obese and Normal-Weight Youths Open

Anita Morandi, Amélie Bonnefond, Stéphane Lobbens, Loïc Yengo, Emanuele Miraglia del Giudice , et al. · 2016

Single nucleotide polymorphisms identified by genome-wide association studies to influence beta-cell function were associated with fasting glucose and indices of insulin secretion in youths, especially in obese children.

Approche protéomique pour la prédiction du syndrome métabolique :étude castémoins nichée au sein de la cohorte Haguenau Open

Julien Bertrand, Mélanie Pétéra, Antony E. Fernandes, Joane Matta, Claire Lévy‐Marchal , et al. · 2015

Cette année les assises sont en partenariat avec le Pôle de compétitivité Lyonbiopôle et le cluster Nutravita, des symposiums thématiques portant sur les interactions entre la recherche académique, l’innovation et l’industrie seront propos…

22nd European Congress on Obesity (ECO2015), Prague, Czech Republic, May 6-9, 2015: Abstracts Open

Joane Matta, Claire Carette, Blandine Comte, Claire Lévy‐Marchal, Estelle Pujos‐Guillot , et al. · 2015

Recent research has suggested that obesity is a stigmatised condition. Concerns with personal inferiority (social rank), shame and self-criticism may impact on weight management behaviours. The current study examined associations between s…

Claire Lévy‐Marchal YOU? Author Swipe