Explanipedia

Management of urinary stones by experts in stone disease (ESD 2025) Open

Athanasios Papatsoris, Bogdan Geavlete, George Daniel Rădăvoi, Mohammed Alameedee, Murtadha Almusafer , et al. · 2025

The formation of kidney stones is a complex biologic process involving interactions among genetic, anatomic, dietary, and environmental factors. Traditional lithogenic models were based on urine supersaturation in relation to the activity …

Bladder Spasm Discomfort After Transurethral Surgery: A Prospective Observational Study of Preoperative, Intraoperative, and Postoperative Predictive Factors Open

Titos Markopoulos, Stamatios Katsimperis, Lazaros Lazarou, Lazaros Tzelves, Iraklis Mitsogiannis , et al. · 2025

Catheter-related bladder discomfort (CRBD) is a common and distressing complication following transurethral urologic procedures such as transurethral resection of the prostate (TURP) and transurethral resection of bladder tumors (TURBT). T…

Catheter-Related Bladder Discomfort: Insights Into Pathophysiology, Clinical Impact, and Management Open

Titos Markopoulos, Stamatios Katsimperis, Lazaros Lazarou, Lazaros Tzelves, Iraklis Mitsogiannis , et al. · 2025

Catheter-related bladder discomfort (CRBD) is a frequent postoperative complication that significantly impacts the quality of recovery in patients undergoing transurethral surgeries. It manifests as suprapubic pain, an intense urge to void…

Reporting and Grading of Complications in Urological Surgery: Current Trends and Future Perspectives Open

Stamatios Katsimperis, Themistoklis Bellos, Ioannis Manolitsis, Ioannis Kyriazis, Panagiotis Angelopoulos , et al. · 2024

There has been a growing need for enhancements in healthcare delivery, especially for the improvement of surgical outcomes. Therefore, implementing consistent reporting of complications enables the evaluation of data quality and facilitate…

The Contemporary Role of Salvage Radical Prostatectomy in the Management of Recurrent Prostate Cancer: An Up-to-Date Review Open

Stamatios Katsimperis, Alexandros Pinitas, Maria Zerva, Themistoklis Bellos, Ioannis Manolitsis , et al. · 2024

Prostate cancer is the second most common cancer among men, with many treatment modalities available for patients, such as radical prostatectomy, external beam radiotherapy, brachytherapy, high-intensity focused ultrasound, cryotherapy, el…

Artificial Intelligence in Urologic Robotic Oncologic Surgery: A Narrative Review Open

Themistoklis Bellos, Ioannis Manolitsis, Stamatios Katsimperis, Patrick Juliebø‐Jones, Georgios Feretzakis , et al. · 2024

With the rapid increase in computer processing capacity over the past two decades, machine learning techniques have been applied in many sectors of daily life. Machine learning in therapeutic settings is also gaining popularity. We analyse…

Circulating Tumour DNA and Its Prognostic Role in Management of Muscle Invasive Bladder Cancer: A Narrative Review of the Literature Open

Konstantinos Kapriniotis, Lazaros Tzelves, Lazaros Lazarou, Maria Mitsogianni, Iraklis Mitsogiannis · 2024

Current management of non-metastatic muscle invasive bladder cancer (MIBC) includes radical cystectomy and cisplatin-based neoadjuvant chemotherapy (NAC), offers a 5-year survival rate of approximately 50% and is associated with significan…

Imaging follow-up for stone patients: a randomized trial using ultrasound Open

Lazaros Tzelves, Panagiotis Angelopoulos, Titos Markopoulos, Athanasios Papatsoris, Iraklis Mitsogiannis , et al. · 2024

BACKGROUND: Urolithiasis is a health condition with high prevalence in modern population, along with frequent recurrences leading to hospital admissions and high radiation exposure from repeated X-rays and CT scans. The lack of a standardi…

Ureteral stent related symptoms: A comparative study Open

Themistoklis Bellos, Ioannis Manolitsis, Stamatios Katsimperis, Panagiotis A. Angelopoulos, Sotirios G. Kapsalos‐Dedes , et al. · 2024

Background: In urology, ureteral stents are used to treat obstructive diseases. Hematuria (54%), fever, discomfort, and lower urinary system symptoms are the predominant symptoms related to ureteral stent.Aim: This article links stent symp…

Surgical techniques to preserve continence after robot-assisted radical prostatectomy Open

Stamatios Katsimperis, Patrick Juliebø‐Jones, Anthony Ta, Zafer Tandoğdu, O. Al-Bermani , et al. · 2023

Radical prostatectomy significantly impacts the inherent anatomy of the male pelvis and the functional mechanisms of urinary continence. Incontinence has a considerable negative influence on the quality of life of patients, as well as thei…

Ureteral stents: A brief narrative review of the different polymeric types, their characteristics, and their connection to stent-related symptoms Open

Themistoklis Bellos, Stamatios Katsimperis, Lazaros Tzelves, Νικόλαος Κωστακόπουλος, Titos P. Markopoulos , et al. · 2023

Background: In routine urological practice, pigtails are frequently utilized to relieve blockage. Early signs of pigtail problems include pain, lower urinary tract symptoms, pain, hematuria (54%) and fever. Seventy percent of patients expe…

Anthropometric characteristics and relationship with non-muscle invasive bladder cancer in Greece: A case-control study Open

Lazaros Tzelves, Stamatios Katsimperis, Themistoklis Bellos, Marinos Berdempes, Iraklis Mitsogiannis , et al. · 2023

Background: Risk factors like smoking, radiation, chronic infections and exposure to occupational chemicals are strongly associated with occurrence of bladder cancer. Association between increased body weight and bladder cancer has been co…

Post Radical Prostatectomy Erectile Dysfunction. A Single Centre Experience Open

Konstantinos Pikramenos, Maria Zachou, Dimitrios Papadopoulos, Athanasios Papatsoris, Ioannis Varkarakis , et al. · 2023

Diagnosis and management of intradiverticular bladder tumours: A pooled analysis of 498 cases Open

Stamatios Katsimperis, Lazaros Tzelves, Themistoklis Bellos, Panagiotis Angelopoulos, Ioannis Tsikopoulos , et al. · 2022

Objective: Intradiverticular bladder tumors (IDBT) are uncommon clinical entities. We reviewed the literature for clinical presentation, diagnosis and therapeutic options to establish recommendations for diagnostic and therapeutic manageme…

Cytoreductive nephrectomy for synchronous metastatic renal cell carcinoma. Is there enough evidence? Open

Stamatios Katsimperis, Lazaros Tzelves, Themistoklis Bellos, Konstantinos Pikramenos, Ioannis Manolitsis , et al. · 2022

Objective: To assess the role of Cytoreductive Nephrectomy for synchronous metastatic Renal Cell Carcinoma patients in the Systemic Therapy era and beyond regarding the Overall Survival, the optimal sequence between Systemic Therapy and Cy…

The effects of method of anaesthesia on the safety and effectiveness of Radical Retropubic Prostatectomy Open

Konstantinos Pikramenos, Maria Zachou, Eleftheria Apostolatou, Dimitrios Papadopoulos, Maria Mitsogianni , et al. · 2022

Objective: The aim of this study is to determine if patients undergoing radical retropubic prostatectomy with localized prostate cancer under combined (epidural-spinal) anaesthesia have any benefit over patients undergoing the procedure un…

Therapeutic Options in Metastatic Renal Cancer Open

Themistoklis Ch. Bellos, Ioannis Manolitsis, Stamatios N. Katsimperis, Ioannis P. Kyriazis, Panagiotis A. Angelopoulos , et al. · 2022

Background: Renal cancer is the 3 rd most common cancer of the urinary tract. It peaks at the age of 64 years and appears more common in men than women. Methods: The purpose of this study is to review the potential therapeutic options in m…

Current Options for Second-Line Systemic Therapy in Metastatic Renal Cell Carcinoma Open

Iraklis Mitsogiannis, Maria Mitsogianni, Maria Papathanassiou, Μαρία Αναγνώστου, Ioannis Tamposis , et al. · 2022

Standard systemic therapy of advanced renal cell carcinoma (RCC) involves targeting angiogenesis, mainly through tyrosine kinase inhibitors (TKI) against the vascular endothelial growth factor receptor (VEGFR) pathway and targeting the imm…

Liposarcoma of the Spermatic Cord Mimicking an Inguinal Hernia: A Case Report and Literature Review Open

Konstantinos Pikramenos, Stamatios Katsimperis, Maria Zachou, Maria Giannakakou, Maria Mitsogianni , et al. · 2022

A Rare Case of an Intermittent Urinary Catheter Discovered Inside a Bladder Open

Konstantinos Pikramenos, Maria Zachou, Georgios Ntounas, Stamatios Katsimperis, Iraklis Mitsogiannis · 2022

Health-Related Quality of Life Assessment in Daily Urologic Practice: A Survey of Greek Urologists Open

Iraklis Mitsogiannis, Maria Mitsogianni, Vissarion Bakalis, Anna Tzortzi de Paz, Panagiotis J. Vlachostergios , et al. · 2022

Iraklis C Mitsogiannis,1 Maria Mitsogianni,1 Vissarion Bakalis,2 Anna Tzortzi de Paz,3 Panagiotis J Vlachostergios,4,* Vassilios Tzortzis3,* 1Second Department of Urology, National and Kapodistrian University of Athens, Sismanoglio General…

Lymphoepithelioma-Like Carcinoma of the Urinary Bladder: A Case Report and Review of the Literature Open

Iraklis Mitsogiannis, Lazaros Tzelves, Maria Mitsogianni, Stephanie Vgenopoulou · 2022

ERCC1 19007 Polymorphism in Greek Patients with Advanced Urothelial Cancer Treated with Platinum-Based Chemotherapy: Effect of the Changing Treatment Paradigm: A Cohort Study by the Hellenic GU Cancer Group Open

Aristotelis Bamias, Konstantinos Koutsoukos, Nikos Gavalas, Roubini Zakopoulou, Kimon Tzannis , et al. · 2021

We previously showed that ERCC1 19007 C>T polymorphism was associated with cancer-specific survival (CSS) after platinum-based chemotherapy in patients with advanced urothelial cancer (aUC). We aimed to confirm this association in a differ…

Relugolix: A new kid on the block among gonadotrophin-releasing hormone antagonists Open

Charalampos Fragkoulis, Ioannis Glykas, Athanasios Dellis, Iraklis Mitsogiannis, Athanasios Papatsoris · 2021

Androgen-deprivation therapy (ADT) is the cornerstone of metastatic prostate cancer treatment. ADT can be achieved through surgical castration, or it may be induced either by gonadotrophin-releasing hormone (GnRH) agonists or GnRH antagoni…

Cefixime versus prulifloxacin as a prophylactic treatment for prostate biopsy: a randomized study Open

Michael Samarinas, Konstantinos Skriapas, Iraklis Mitsogiannis, Stavros Gravas, Anastasios Karatzas , et al. · 2020

Prophylactic cefixime could be suggested as effective in preventing severe UTIs after prostate biopsy in the era of high bacterial resistance to fluoroquinolones.

Management of stent-related symptoms with the use of α-blockers: A meta-analysis Open

Konstantinos Deliveliotis, Athanasios Papatsoris, Andreas Skolarikos, Iraklis Mitsogiannis, Kimon Tzannis , et al. · 2019

Objectives: To assess the effectiveness of α-blockers at reducing stent-related morbidity compared to placebo using the Ureteric Symptom Score questionnaire (USSQ) at particular time points as originally set by the developers of the…

Renal Hematomas After Ureterolithotripsy: Report of Four Cases Open

Iraklis Mitsogiannis, Νικόλαος Κωστακόπουλος, Lazaros Lazarou, Konstantinos Deliveliotis, Theodoros Karagiotis , et al. · 2019

Background: Renal hematomas, although relatively rare, are potentially life-threatening complications after ureterolithotripsy. Case Presentation: We present four cases of renal hematomas that occurred in our de…

Treatment of relapsed urothelial bladder cancer with vinflunine Open

Nikolaos Pistamaltzian, Kimon Tzannis, Vassiliki Pissanidou, Stavros D. Peroukidis, Georgia Milaki , et al. · 2015

Relapsed urothelial cancer represents an unmet medical need. Vinflunine is a third-generation antimicrotubuline inhibitor and is currently the only approved drug for second-line treatment across the European Union. We conducted a retrospec…

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