César A. Moran
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View article: Pulmonary Fungal Infections in a Tertiary Cancer Center: A Morphological Correlation of 160 Cases with CT and PET Imaging
Pulmonary Fungal Infections in a Tertiary Cancer Center: A Morphological Correlation of 160 Cases with CT and PET Imaging Open
Background: Pulmonary fungal infections can mimic malignancies, especially in patients with a prior cancer diagnosis. This study presents 160 patients who were suspected to have malignancies but were diagnosed with fungal infections. Metho…
View article: Effectiveness of interventions for informal caregivers of people with end-stage chronic illness: a systematic review
Effectiveness of interventions for informal caregivers of people with end-stage chronic illness: a systematic review Open
Background People living with advanced, non-malignant chronic conditions often have extensive and complex care needs. Informal or family caregivers often provide the care and support needed by those with advanced chronic conditions at home…
View article: Unexpected Mediastinal Mass Etiology in B-Acute Lymphoblastic Leukemia
Unexpected Mediastinal Mass Etiology in B-Acute Lymphoblastic Leukemia Open
Leukemic masses are a known complication in patients with hematologic malignancies. Here we present a case regarding a patient with recently diagnosed B-acute lymphoblastic leukemia (B-ALL) who presented with multiple sites of extramedulla…
View article: Metastatic extraneural glioblastoma diagnosed with molecular testing
Metastatic extraneural glioblastoma diagnosed with molecular testing Open
Glioblastoma, the most common malignant brain tumor in adults, is associated with a median overall survival duration of less than 2 years. Extraneural metastases occur in less than 1% of all patients with glioblastoma. The mechanism of ext…
View article: Integrative genomic and transcriptomic profiling of pulmonary sarcomatoid carcinoma identifies molecular subtypes associated with distinct immune features and clinical outcomes
Integrative genomic and transcriptomic profiling of pulmonary sarcomatoid carcinoma identifies molecular subtypes associated with distinct immune features and clinical outcomes Open
Background Pulmonary sarcomatoid carcinoma (PSC) is a rare and aggressive subtype of non‐small cell lung cancer (NSCLC), characterized by the presence of epithelial and sarcoma‐like components. The molecular and immune landscape of PSC has…
View article: Uncommon Tumors of the Lung: Recently Described and Rediscovered Tumors
Uncommon Tumors of the Lung: Recently Described and Rediscovered Tumors Open
Context.— The great majority of primary pulmonary neoplasms are represented by non–small cell carcinomas—adenocarcinoma and squamous cell carcinoma. In addition, there is another group of neoplasms such as those of neuroendocrine origin th…
View article: Primary Pulmonary Carcinomas with Spindle and/or Giant Cell Features: A Review with Emphasis in Classification and Pitfalls in Diagnosis
Primary Pulmonary Carcinomas with Spindle and/or Giant Cell Features: A Review with Emphasis in Classification and Pitfalls in Diagnosis Open
Primary carcinomas of the lung are vastly represented by the conventional types of adenocarcinomas or squamous cell carcinomas. However, there are other types of non-small cell carcinomas that although uncommon represent a meaningful group…
View article: Primary Pulmonary Carcinomas With Spindle And/or Giant Cell Features: A Review With Emphasis in Classification and Pitfalls in Diagnosis
Primary Pulmonary Carcinomas With Spindle And/or Giant Cell Features: A Review With Emphasis in Classification and Pitfalls in Diagnosis Open
Primary carcinomas of the lung are vastly represented by the conventional types of adenocarcinomas or squamous cell carcinomas. However, there are other types of non-small cell carcinomas that although uncommon represent a meaningful group…
View article: Immune cellular patterns of distribution affect outcomes of patients with non-small cell lung cancer
Immune cellular patterns of distribution affect outcomes of patients with non-small cell lung cancer Open
Studying the cellular geographic distribution in non-small cell lung cancer is essential to understand the roles of cell populations in this type of tumor. In this study, we characterize the spatial cellular distribution of immune cell pop…
View article: Data from Epidermal Growth Factor Receptor Abnormalities in the Pathogenesis and Progression of Lung Adenocarcinomas
Data from Epidermal Growth Factor Receptor Abnormalities in the Pathogenesis and Progression of Lung Adenocarcinomas Open
To identify the characteristics and sequence of epidermal growth factor receptor (EGFR) abnormalities relevant to the pathogenesis and progression of lung adenocarcinoma, we performed a precise mapping analysis of EGFR mutation, gene copy …
View article: Data from Epidermal Growth Factor Receptor Abnormalities in the Pathogenesis and Progression of Lung Adenocarcinomas
Data from Epidermal Growth Factor Receptor Abnormalities in the Pathogenesis and Progression of Lung Adenocarcinomas Open
To identify the characteristics and sequence of epidermal growth factor receptor (EGFR) abnormalities relevant to the pathogenesis and progression of lung adenocarcinoma, we performed a precise mapping analysis of EGFR mutation, gene copy …
View article: Perspective on this Article from Epidermal Growth Factor Receptor Abnormalities in the Pathogenesis and Progression of Lung Adenocarcinomas
Perspective on this Article from Epidermal Growth Factor Receptor Abnormalities in the Pathogenesis and Progression of Lung Adenocarcinomas Open
Perspective on this Article from Epidermal Growth Factor Receptor Abnormalities in the Pathogenesis and Progression of Lung Adenocarcinomas
View article: Perspective on this Article from Epidermal Growth Factor Receptor Abnormalities in the Pathogenesis and Progression of Lung Adenocarcinomas
Perspective on this Article from Epidermal Growth Factor Receptor Abnormalities in the Pathogenesis and Progression of Lung Adenocarcinomas Open
Perspective on this Article from Epidermal Growth Factor Receptor Abnormalities in the Pathogenesis and Progression of Lung Adenocarcinomas
View article: Supplementary Table 2 from EZH2 Protein Expression Associates with the Early Pathogenesis, Tumor Progression, and Prognosis of Non–Small Cell Lung Carcinoma
Supplementary Table 2 from EZH2 Protein Expression Associates with the Early Pathogenesis, Tumor Progression, and Prognosis of Non–Small Cell Lung Carcinoma Open
PDF file 68K, C-index of Cox proportional hazard models of outcome of lung adenocarcinoma patients
View article: Supplementary Data from Immunohistochemical Expression of Estrogen and Progesterone Receptors Identifies a Subset of NSCLCs and Correlates with <i>EGFR</i> Mutation
Supplementary Data from Immunohistochemical Expression of Estrogen and Progesterone Receptors Identifies a Subset of NSCLCs and Correlates with <i>EGFR</i> Mutation Open
Supplementary Data from Immunohistochemical Expression of Estrogen and Progesterone Receptors Identifies a Subset of NSCLCs and Correlates with EGFR Mutation
View article: Supplementary Data from Abnormalities of the <i>TITF-1</i> Lineage-Specific Oncogene in NSCLC: Implications in Lung Cancer Pathogenesis and Prognosis
Supplementary Data from Abnormalities of the <i>TITF-1</i> Lineage-Specific Oncogene in NSCLC: Implications in Lung Cancer Pathogenesis and Prognosis Open
Supplementary Figures S1-S2; Supplementary Tables S1-S5.
View article: Supplementary Table 1 from EZH2 Protein Expression Associates with the Early Pathogenesis, Tumor Progression, and Prognosis of Non–Small Cell Lung Carcinoma
Supplementary Table 1 from EZH2 Protein Expression Associates with the Early Pathogenesis, Tumor Progression, and Prognosis of Non–Small Cell Lung Carcinoma Open
PDF file 87K, Summary of multivariate analysis of outcome in lung adenocarcinoma patients by combined expression of EZH2 and TTF-1
View article: Supplementary Data from Abnormalities of the <i>TITF-1</i> Lineage-Specific Oncogene in NSCLC: Implications in Lung Cancer Pathogenesis and Prognosis
Supplementary Data from Abnormalities of the <i>TITF-1</i> Lineage-Specific Oncogene in NSCLC: Implications in Lung Cancer Pathogenesis and Prognosis Open
Supplementary Figures S1-S2; Supplementary Tables S1-S5.
View article: Supplementary Figures 1-4 from Robust Gene Expression Signature from Formalin-Fixed Paraffin-Embedded Samples Predicts Prognosis of Non–Small-Cell Lung Cancer Patients
Supplementary Figures 1-4 from Robust Gene Expression Signature from Formalin-Fixed Paraffin-Embedded Samples Predicts Prognosis of Non–Small-Cell Lung Cancer Patients Open
PDF file - 148K
View article: Supplementary Table 2 from Image Analysis–based Assessment of PD-L1 and Tumor-Associated Immune Cells Density Supports Distinct Intratumoral Microenvironment Groups in Non–small Cell Lung Carcinoma Patients
Supplementary Table 2 from Image Analysis–based Assessment of PD-L1 and Tumor-Associated Immune Cells Density Supports Distinct Intratumoral Microenvironment Groups in Non–small Cell Lung Carcinoma Patients Open
Median TAIC density by mm2 in the intratumoral and peritumoral compartments of lung ADC and SqCC specimens.
View article: Supplementary Tables from Genomic Landscape Established by Allelic Imbalance in the Cancerization Field of a Normal Appearing Airway
Supplementary Tables from Genomic Landscape Established by Allelic Imbalance in the Cancerization Field of a Normal Appearing Airway Open
Supplementary Tables 1-3 Supplementary Table 1. Location and number of NSCLC, normal and field of cancerization specimens analyzed for genome-wide allelic imbalance Supplementary Table 2. Summary of identified allelic imbalance events in t…
View article: Supplementary Tables from Genomic Landscape Established by Allelic Imbalance in the Cancerization Field of a Normal Appearing Airway
Supplementary Tables from Genomic Landscape Established by Allelic Imbalance in the Cancerization Field of a Normal Appearing Airway Open
Supplementary Tables 1-3 Supplementary Table 1. Location and number of NSCLC, normal and field of cancerization specimens analyzed for genome-wide allelic imbalance Supplementary Table 2. Summary of identified allelic imbalance events in t…
View article: Supplementary Table 2 from Image Analysis–based Assessment of PD-L1 and Tumor-Associated Immune Cells Density Supports Distinct Intratumoral Microenvironment Groups in Non–small Cell Lung Carcinoma Patients
Supplementary Table 2 from Image Analysis–based Assessment of PD-L1 and Tumor-Associated Immune Cells Density Supports Distinct Intratumoral Microenvironment Groups in Non–small Cell Lung Carcinoma Patients Open
Median TAIC density by mm2 in the intratumoral and peritumoral compartments of lung ADC and SqCC specimens.
View article: Legend Supplementary Figure 1 from EZH2 Protein Expression Associates with the Early Pathogenesis, Tumor Progression, and Prognosis of Non–Small Cell Lung Carcinoma
Legend Supplementary Figure 1 from EZH2 Protein Expression Associates with the Early Pathogenesis, Tumor Progression, and Prognosis of Non–Small Cell Lung Carcinoma Open
PDF file 55K, Legend Supplementary Figure 1
View article: Supplementary Figure 2 from A Phase I/II Study of Neoadjuvant Cisplatin, Docetaxel, and Nintedanib for Resectable Non–Small Cell Lung Cancer
Supplementary Figure 2 from A Phase I/II Study of Neoadjuvant Cisplatin, Docetaxel, and Nintedanib for Resectable Non–Small Cell Lung Cancer Open
Supplementary Figure 2
View article: Supplementary Tables 1-7 from Robust Gene Expression Signature from Formalin-Fixed Paraffin-Embedded Samples Predicts Prognosis of Non–Small-Cell Lung Cancer Patients
Supplementary Tables 1-7 from Robust Gene Expression Signature from Formalin-Fixed Paraffin-Embedded Samples Predicts Prognosis of Non–Small-Cell Lung Cancer Patients Open
PDF file - 153K
View article: Supplementary Methods from Robust Gene Expression Signature from Formalin-Fixed Paraffin-Embedded Samples Predicts Prognosis of Non–Small-Cell Lung Cancer Patients
Supplementary Methods from Robust Gene Expression Signature from Formalin-Fixed Paraffin-Embedded Samples Predicts Prognosis of Non–Small-Cell Lung Cancer Patients Open
PDF file - 75K
View article: Supplementary Report from Robust Gene Expression Signature from Formalin-Fixed Paraffin-Embedded Samples Predicts Prognosis of Non–Small-Cell Lung Cancer Patients
Supplementary Report from Robust Gene Expression Signature from Formalin-Fixed Paraffin-Embedded Samples Predicts Prognosis of Non–Small-Cell Lung Cancer Patients Open
PDF file - 315K, Sweave Report
View article: Supplementary Table 2 from EZH2 Protein Expression Associates with the Early Pathogenesis, Tumor Progression, and Prognosis of Non–Small Cell Lung Carcinoma
Supplementary Table 2 from EZH2 Protein Expression Associates with the Early Pathogenesis, Tumor Progression, and Prognosis of Non–Small Cell Lung Carcinoma Open
PDF file 68K, C-index of Cox proportional hazard models of outcome of lung adenocarcinoma patients
View article: Data from EZH2 Protein Expression Associates with the Early Pathogenesis, Tumor Progression, and Prognosis of Non–Small Cell Lung Carcinoma
Data from EZH2 Protein Expression Associates with the Early Pathogenesis, Tumor Progression, and Prognosis of Non–Small Cell Lung Carcinoma Open
Purpose: Enhancer of zeste homolog 2 (EZH2) promotes carcinogenesis by epigenetically silencing tumor suppressor genes. We studied EZH2 expression by immunohistochemistry in a large series of non–small cell lung carcinomas (NSCLC) in assoc…