C. Noel Bairey Merz
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View article: Persistent chest pain trends at 3 years in women with INOCA vs. obstructive CAD: results from the NHLBI-sponsored women’s ischemia syndrome evaluation (WISE)
Persistent chest pain trends at 3 years in women with INOCA vs. obstructive CAD: results from the NHLBI-sponsored women’s ischemia syndrome evaluation (WISE) Open
Aims Individuals with suspected ischaemia but no obstructive coronary arteries (INOCA) experience persistent chest pain (PChP) at rates comparable to those with obstructive coronary artery disease (CAD). We analysed the National Heart, Lun…
View article: A cross-sectional comparison of invasive and noninvasive aortic pulse wave velocity measurement in patients with or at risk for heart failure with preserved ejection fraction
A cross-sectional comparison of invasive and noninvasive aortic pulse wave velocity measurement in patients with or at risk for heart failure with preserved ejection fraction Open
MRI measurement of aPWV shows good agreement with traditional invasive and noninvasive measurements in participants with or at risk for HFpEF. Reliable measurement of arterial stiffness combined with cardiac MRI measures of ventricular rem…
View article: Allostatic Load Mediates Associations Between Race and Ethnicity and Hypertensive Disorders of Pregnancy
Allostatic Load Mediates Associations Between Race and Ethnicity and Hypertensive Disorders of Pregnancy Open
OBJECTIVE: To evaluate whether chronic stress exposure, measured by allostatic load (a biological measure of chronic stress embodiment, including stressors exacerbated by structural inequities [eg, structural racism]) and patient-reported …
View article: Is spontaneous preterm delivery associated with impaired arterial stiffness at 6 months postpartum?
Is spontaneous preterm delivery associated with impaired arterial stiffness at 6 months postpartum? Open
Women with sPTD had no significant change in AIx75 while term delivery demonstrated significant decreases at 6 months postpartum. This may contribute to mechanistic pathway and future CVD risk understanding for women with sPTD. Further res…
View article: Association between adverse pregnancy outcomes and awareness of cardiovascular risk factors: A nuMoM2b‐HHS secondary analysis
Association between adverse pregnancy outcomes and awareness of cardiovascular risk factors: A nuMoM2b‐HHS secondary analysis Open
Background Adverse pregnancy outcomes (APOs) affect 10%–20% of pregnancies and are associated with increased risk of cardiovascular disease. Objective To determine whether the history of APO is associated with a person's awareness of their…
View article: A novel two-sample Mendelian randomization framework integrating common and rare variants: application to assess the effect of HDL-C on preeclampsia risk
A novel two-sample Mendelian randomization framework integrating common and rare variants: application to assess the effect of HDL-C on preeclampsia risk Open
Mendelian randomization (MR) has become an important technique for establishing causal relationships between risk factors and health outcomes. By using genetic variants as instrumental variables, it can mitigate bias due to confounding and…
View article: Remote blood sampling differential protein expression associated with persistent hypertension following a hypertensive disorder of pregnancy
Remote blood sampling differential protein expression associated with persistent hypertension following a hypertensive disorder of pregnancy Open
Objective Hypertensive disorders of pregnancy are associated with future cardiovascular risk, however, the underlying mechanisms are unclear. We sought to test the feasibility of postpartum remote blood sampling following a hypertensive di…
View article: Psychosocial and clinical characteristics in Takotsubo syndrome
Psychosocial and clinical characteristics in Takotsubo syndrome Open
Background Takotsubo Syndrome (TTS) is an acute form of heart failure that disproportionately impacts post-menopausal women. The brain-heart connection is considered a pathway for TTS pathophysiology leading to investigations of the role o…
View article: Myocardial Ischaemic Syndromes: Shifting from a Coronary-centric to a Substrate-based Nomenclature is More Accurate and Inclusive
Myocardial Ischaemic Syndromes: Shifting from a Coronary-centric to a Substrate-based Nomenclature is More Accurate and Inclusive Open
This article highlights the rationale for a more accurate and inclusive classification that does not focus solely on epicardial coronary lesions as the causa sine qua non for angina and myocardial ischaemia in all patients but rather repre…
View article: Statin Use Among Women and Men Following Coronary Artery Bypass Surgery
Statin Use Among Women and Men Following Coronary Artery Bypass Surgery Open
Background Limited data exist on sex differences in guideline‐recommended statin therapy for secondary prevention after coronary artery bypass surgery (CABG). We examined sex differences in statin use after CABG and the association between…
View article: Cardiac Abnormalities in Hispanic/Latina Women With Prior De Novo Hypertensive Disorders of Pregnancy
Cardiac Abnormalities in Hispanic/Latina Women With Prior De Novo Hypertensive Disorders of Pregnancy Open
BACKGROUND: Hypertensive disorders of pregnancy (HDP) are associated with long-term maternal risks for cardiovascular disease for reasons that remain incompletely understood. METHODS: The HCHS/SOL (Hispanic Community Health Study/Study of …
View article: A randomized controlled trial of meditation and health education on carotid intima-media thickness and major adverse cardiovascular events in Black men and women
A randomized controlled trial of meditation and health education on carotid intima-media thickness and major adverse cardiovascular events in Black men and women Open
Introduction Black Americans suffer from disproportionately high rates of cardiovascular disease (CVD). Psychosocial stress contributes to this disparity. Previous studies reported that the Transcendental Meditation (TM) technique reduced …
View article: Barriers and solutions in women’s health research and clinical care: a call to action
Barriers and solutions in women’s health research and clinical care: a call to action Open
It is now recognized that there are significant differences between the sexes affecting prevalence, incidence, and severity over a broad range of diseases, although the extent of the differences is not fully elucidated. Until the early 199…