Salvatore Cappabianca
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View article: Intratumoral calcifications in pancreatic neoplasms on unenhanced CT: frequency and diagnostic implications
Intratumoral calcifications in pancreatic neoplasms on unenhanced CT: frequency and diagnostic implications Open
Purpose Serous cystadenomas (SCAs), solid pseudopapillary neoplasms (SPNs), neuroendocrine neoplasms (NENs), and mucinous cystic neoplasms (MCNs) are pancreatic tumors that frequently develop calcifications. Identifying the presence and pa…
View article: Multimodal Imaging of Ductal Carcinoma In Situ: A Single-Center Study of 75 Cases
Multimodal Imaging of Ductal Carcinoma In Situ: A Single-Center Study of 75 Cases Open
Introduction: Ductal carcinoma in situ (DCIS) is a non-invasive precursor of breast cancer, usually detected on mammography as clustered microcalcifications. Many cases, however, lack calcifications and require complementary imaging. This …
View article: GLP-1 Receptor Agonists Are Associated with Reduced Ascending Aorta Dilatation in Patients with Type 2 Diabetes: A Prospective Study
GLP-1 Receptor Agonists Are Associated with Reduced Ascending Aorta Dilatation in Patients with Type 2 Diabetes: A Prospective Study Open
The aim was to assess the impact of glucagon-like peptide-1 receptor agonists (GLP-1 RA) treatment on the progression of ascending aorta dilatation in patients with type 2 diabetes mellitus (T2DM). A total of 127 T2DM patients with subclin…
View article: Intra-plaque vascularization assessed in contrast-enhanced ultrasound predicts cardiovascular events in type 2 diabetes with no significant carotid atherosclerotic stenosis: a prospective study with therapeutic implications for SGLT2 inhibitor use
Intra-plaque vascularization assessed in contrast-enhanced ultrasound predicts cardiovascular events in type 2 diabetes with no significant carotid atherosclerotic stenosis: a prospective study with therapeutic implications for SGLT2 inhibitor use Open
Aims Patients with type 2 diabetes mellitus (T2DM) and no significant carotid stenosis are often considered at moderate cardiovascular risk. However, some may harbour biologically active plaques. Intra-plaque vascularization (IPV), detecta…
View article: LIquid biopsy and Diagnostic of Imaging (LIDIA) for the definition of prognostic biomarkers and personalised therapies in lung cancer: a clinical trial
LIquid biopsy and Diagnostic of Imaging (LIDIA) for the definition of prognostic biomarkers and personalised therapies in lung cancer: a clinical trial Open
View article: 18F-FDG PET/CT Findings to Improve Confidence in Distinguishing Lung External Beam Radiotherapy Side Effects
18F-FDG PET/CT Findings to Improve Confidence in Distinguishing Lung External Beam Radiotherapy Side Effects Open
Modern external beam radiotherapy (EBRT) on lung cancer improved dose distribution thanks to advanced dose calculation algorithms, but side effects and relapses can occur in any case onset. Differential diagnosis of relapses and side effec…
View article: Clinical Outcomes and Predictive Factors in NSCLC after Surgery: Findings from the RAC-TAC Study
Clinical Outcomes and Predictive Factors in NSCLC after Surgery: Findings from the RAC-TAC Study Open
Distant metastases remain the main recurrence type. The extent of lymph node dissection and the count of positive nodes significantly influence recurrence patterns. These findings support integrating systemic and local therapies to improve…
View article: In-Depth Exploration of Radiation-Induced Cell Death Mechanisms in Tumor
In-Depth Exploration of Radiation-Induced Cell Death Mechanisms in Tumor Open
Radiation therapy is a cornerstone of cancer treatment, targeting tumor cells through DNA damage and subsequent induction of various forms of cell death. This chapter explores the multifaceted biological effects of Radiation therapy (RT), …
View article: Whole-body magnetic resonance imaging for cutaneous melanoma staging: A scientific review
Whole-body magnetic resonance imaging for cutaneous melanoma staging: A scientific review Open
BACKGROUND Cutaneous melanoma is an aggressive skin cancer with high metastatic potential. Accurate staging is critical to guide therapeutic strategies and improve prognosis. Whole-body magnetic resonance imaging (WB-MRI), particularly whe…
View article: Carnosol modulates mPGES-1/PPAR-γ biological axis: from in silico to in vivo clinical imaging and investigations
Carnosol modulates mPGES-1/PPAR-γ biological axis: from in silico to in vivo clinical imaging and investigations Open
The onset and progression of the inflammatory response and reaction are complex mechanisms dependent on the balance of activity between different and counteracting targets and enzymatic systems. The understanding and, even more importantly…
View article: Colorectal cancer liver metastases: A radiologic point of view
Colorectal cancer liver metastases: A radiologic point of view Open
Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide. Despite advances in early detection and treatment, approximately half of patients with CRC develop liver metastases (LM), complicating therape…
View article: Diagnostic Accuracy of Contrast-Enhanced Ultrasound in Differentiating RCC from AML in Small Hyperechoic Renal Masses (≤ 3 cm): A Retrospective Single-Center Study
Diagnostic Accuracy of Contrast-Enhanced Ultrasound in Differentiating RCC from AML in Small Hyperechoic Renal Masses (≤ 3 cm): A Retrospective Single-Center Study Open
CEUS accurately differentiates RCC from AML in small hyperechoic renal masses. Rapid wash-out and perilesional rim-like enhancement are independent predictors of malignancy and may guide biopsy versus surveillance decisions.
View article: Validation of a novel imaging-guided and anatomy-based classification system for anorectal fistulas: a retrospective clinical evaluation study
Validation of a novel imaging-guided and anatomy-based classification system for anorectal fistulas: a retrospective clinical evaluation study Open
Purpose: This study was conducted to evaluate the validity of a new imaging-guided, anatomy-based classification of anorectal fistulas in defining disease severity and predicting surgical outcomes.Methods: This multicenter, retrospective c…
View article: “Aging and epigenetic implications in radiotherapy: The promise of BNCT”
“Aging and epigenetic implications in radiotherapy: The promise of BNCT” Open
View article: Correction: Thymic hyperplasia is accurate to detect new-onset Graves’ hyperthyroidism and resolves after restoring euthyroidism
Correction: Thymic hyperplasia is accurate to detect new-onset Graves’ hyperthyroidism and resolves after restoring euthyroidism Open
View article: Multidisciplinary analysis of ancient human skeletal remains using computed tomography: A case study from Cumae, Italy
Multidisciplinary analysis of ancient human skeletal remains using computed tomography: A case study from Cumae, Italy Open
CT analysis provides detailed insights into bone integrity and pathologies, facilitating comprehensive anthropological examinations. Multidisciplinary collaboration is essential for accurate interpretations of ancient human remains. This s…
View article: High-Frequency and Ultra-High-Frequency Ultrasound in Dermatologic Diseases and Aesthetic Medicine
High-Frequency and Ultra-High-Frequency Ultrasound in Dermatologic Diseases and Aesthetic Medicine Open
Dermatologic ultrasonography applications are rapidly growing in all skin fields. Thanks to very high spatial resolution, high-frequency and ultra-high-frequency ultrasound can evaluate smaller structures, allowing us to improve diagnosis …
View article: A Multimodal Machine Learning Model in Pneumonia Patients Hospital Length of Stay Prediction
A Multimodal Machine Learning Model in Pneumonia Patients Hospital Length of Stay Prediction Open
Hospital overcrowding, driven by both structural management challenges and widespread medical emergencies, has prompted extensive research into machine learning (ML) solutions for predicting patient length of stay (LOS) to optimize bed all…
View article: Diagnostic Value of Contrast-Enhanced Ultrasound in Differentiating Malignant from Benign Small Renal Masses After CT/MRI
Diagnostic Value of Contrast-Enhanced Ultrasound in Differentiating Malignant from Benign Small Renal Masses After CT/MRI Open
Background: The aim of this study was to assess the diagnostic performance of contrast-enhanced ultrasound (CEUS) in characterizing small renal masses (SRMs) measuring less than 3 cm and in distinguishing between malignant and benign SRMs.…
View article: Recurrent Versus Metastatic Head and Neck Cancer: An Evolving Landscape and the Role of Immunotherapy
Recurrent Versus Metastatic Head and Neck Cancer: An Evolving Landscape and the Role of Immunotherapy Open
Squamous cell carcinoma of the head and neck (SCCHN) is among the ten most common cancers worldwide, with advanced SCCHN presenting with a 5-year survival of 34% in the case of nodal involvement and 8% in the case of metastatic disease. Di…
View article: The Role of Artificial Intelligence on Tumor Boards: Perspectives from Surgeons, Medical Oncologists and Radiation Oncologists
The Role of Artificial Intelligence on Tumor Boards: Perspectives from Surgeons, Medical Oncologists and Radiation Oncologists Open
The integration of multidisciplinary tumor boards (MTBs) is fundamental in delivering state-of-the-art cancer treatment, facilitating collaborative diagnosis and management by a diverse team of specialists. Despite the clear benefits in pe…
View article: Genetic profiling in radiotherapy: a comprehensive review
Genetic profiling in radiotherapy: a comprehensive review Open
This comprehensive review explores the pivotal role of radiotherapy in cancer treatment, emphasizing the diverse applications of genetic profiling. The review highlights genetic markers for predicting radiation toxicity, enabling personali…
View article: Delta radiomics: an updated systematic review
Delta radiomics: an updated systematic review Open
View article: Associations between Radiomics and Genomics in Non-Small Cell Lung Cancer Utilizing Computed Tomography and Next-Generation Sequencing: An Exploratory Study
Associations between Radiomics and Genomics in Non-Small Cell Lung Cancer Utilizing Computed Tomography and Next-Generation Sequencing: An Exploratory Study Open
Background: Radiomics, an evolving paradigm in medical imaging, involves the quantitative analysis of tumor features and demonstrates promise in predicting treatment responses and outcomes. This study aims to investigate the predictive cap…
View article: Identification of perineural invasion at imaging staging as a novel potential risk factor in rectal cancer: A case report
Identification of perineural invasion at imaging staging as a novel potential risk factor in rectal cancer: A case report Open
Treatment of rectal cancer has improved over the years thanks to a multidisciplinary approach. A correct staging has a fundamental role for risk stratification and to define the best treatment for each patient. Unfortunately, approximately…
View article: Case Report: False aneurysm as a late unusual complication of the aortofemoral bypass graft in a patient with critical leg ischemic symptoms: interesting case
Case Report: False aneurysm as a late unusual complication of the aortofemoral bypass graft in a patient with critical leg ischemic symptoms: interesting case Open
Aortofemoral bypass surgery is a common procedure for treating aortoiliac occlusive disease, also known as Leriche syndrome, which can cause lower extremity ischemic symptoms. Diagnostic imaging techniques play a crucial role in managing p…
View article: Reliability of Ultrasonographic Assessment of Depth of Invasion and Tumor Thickness in Intraoral Mucosa Lesions: A Preliminary Experience
Reliability of Ultrasonographic Assessment of Depth of Invasion and Tumor Thickness in Intraoral Mucosa Lesions: A Preliminary Experience Open
Introduction: Despite the progress made in multidisciplinary care, there has been little improvement in the oncologic outcomes of oral cavity squamous cell carcinomas (OSCCs). In the latest edition of the TNM staging, “depth of invasion” (…
View article: Radiogenomics Relationship of Non-small Cell Lung Cancer: Preliminary Results
Radiogenomics Relationship of Non-small Cell Lung Cancer: Preliminary Results Open
Radiology 2 Mins 11th April Quantitative CT Analysis of Hepatocellular Carcinoma Nodules in Liver Transplant Candidates: Impact of Volume of Interest and Contrast Phase on Recurrence Prediction
View article: Thymic hyperplasia is accurate to detect new-onset Graves’ hyperthyroidism and resolves after restoring euthyroidism
Thymic hyperplasia is accurate to detect new-onset Graves’ hyperthyroidism and resolves after restoring euthyroidism Open
View article: New perspectives on inoperable early-stage lung cancer management: Clinicians, physicists, and biologists unveil strategies and insights
New perspectives on inoperable early-stage lung cancer management: Clinicians, physicists, and biologists unveil strategies and insights Open
This work provides a comprehensive overview of the current landscape of lung cancer, emphasizing the global significance of the disease and the challenges associated with its diagnosis and treatment. The authors highlight the prevalence of…