Jean‐Christophe Rozé
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View article: Twin pregnancy with the first twin in breech presentation: Survival and neurodevelopmental outcome of preterm infants at a corrected age of 2 years
Twin pregnancy with the first twin in breech presentation: Survival and neurodevelopmental outcome of preterm infants at a corrected age of 2 years Open
View article: Association between skin-to-skin contact and cognition and behaviour at 5 years in children born at 24–31 weeks’ gestation: a secondary analysis of a national population-based prospective cohort study
Association between skin-to-skin contact and cognition and behaviour at 5 years in children born at 24–31 weeks’ gestation: a secondary analysis of a national population-based prospective cohort study Open
View article: Experience and lessons learned relating to investigational product supply in the design and delivery of a paediatric investigator-initiated clinical trial
Experience and lessons learned relating to investigational product supply in the design and delivery of a paediatric investigator-initiated clinical trial Open
View article: Neurodevelopmental outcomes at age 5 years among children born very preterm and surviving after persistent pulmonary hypertension of the newborn: EPIPAGE-2 cohort study
Neurodevelopmental outcomes at age 5 years among children born very preterm and surviving after persistent pulmonary hypertension of the newborn: EPIPAGE-2 cohort study Open
In this nationwide population-based cohort of extremely preterm and very preterm infants, moderate to severe overall neurodevelopmental disability at age 5 was significantly associated with neonatal PH.
View article: Nutritional value of organic food in children
Nutritional value of organic food in children Open
In Europe, organic food must comply with specific regulations which do not include nutritional criteria. The ability of organic food to meet the nutritional needs of children is not assessed. This narrative review discusses the nutritional…
View article: Very preterm gut microbiota development from the first week of life to 3.5 years of age: a prospective longitudinal multicenter study
Very preterm gut microbiota development from the first week of life to 3.5 years of age: a prospective longitudinal multicenter study Open
This study analyzed the longitudinal evolution of intestinal microbiota in very preterm neonates (PN) during and after their hospitalization. The bacterial 16S rRNA gene sequencing approach was applied for the analysis of fecal samples ( n…
View article: TREOCAPA: prophylactic treatment of the ductus arteriosus in preterm infants by acetaminophen—statistical analysis plan for the randomized phase III group sequential trial
TREOCAPA: prophylactic treatment of the ductus arteriosus in preterm infants by acetaminophen—statistical analysis plan for the randomized phase III group sequential trial Open
gov: NCT04459117, registered on July 7, 2020.
View article: School-entry age and academic difficulties at 7 years of age in children born very preterm: A call for age-corrected schooling
School-entry age and academic difficulties at 7 years of age in children born very preterm: A call for age-corrected schooling Open
Starting school a year earlier than anticipated during pregnancy was associated with an increased rate of AD at age 7 in children born very preterm, independently of their neurodevelopment at age 5 assessed by ASQ. Basing school entry age …
View article: Projet exploratoire SYALSA -LactOMICS: Le lait maternel : une interface environnement - système d'alimentation durable - santé
Projet exploratoire SYALSA -LactOMICS: Le lait maternel : une interface environnement - système d'alimentation durable - santé Open
International audience
View article: Population Pharmacokinetics of Intravenous Paracetamol and Its Metabolites in Extreme Preterm Neonates in the Context of Patent Ductus Arteriosus Treatment
Population Pharmacokinetics of Intravenous Paracetamol and Its Metabolites in Extreme Preterm Neonates in the Context of Patent Ductus Arteriosus Treatment Open
The relative proportions of the metabolic pathways were characterised with gestational age. In the range of observed drug exposures, no association was found with clinical response or liver biomarkers. These findings may suggest that parac…
View article: Device Closure of Hemodynamically Significant Patent Ductus Arteriosus in Premature Infants
Device Closure of Hemodynamically Significant Patent Ductus Arteriosus in Premature Infants Open
View article: TREOCAPA: Prophylactic Treatment of the Ductus Arteriosus in Preterm Infants by Acetaminophen. Statistical analysis plan for the randomized phase III group sequential trial
TREOCAPA: Prophylactic Treatment of the Ductus Arteriosus in Preterm Infants by Acetaminophen. Statistical analysis plan for the randomized phase III group sequential trial Open
Background Persistent patency of the ductus arteriosus (PDA) has challenged neonatologists for more than 40 years. Controversies persist about the management of PDA in extremely preterm infants. PDA is associated with morbidities but no th…
View article: Growth charts for use at birth and in the neonatal period: Recommendations of the French Neonatal Society
Growth charts for use at birth and in the neonatal period: Recommendations of the French Neonatal Society Open
Introduction The use of different growth charts can lead to confusion in discussions between professionals. There are obstetric charts (of fetal growth) and neonatal charts (of measurements at birth and of postnatal growth). These charts c…
View article: Pao 2 and Mortality in Neonatal Extracorporeal Membrane Oxygenation: Retrospective Analysis of the Extracorporeal Life Support Organization Registry, 2015–2020*
Pao 2 and Mortality in Neonatal Extracorporeal Membrane Oxygenation: Retrospective Analysis of the Extracorporeal Life Support Organization Registry, 2015–2020* Open
OBJECTIVES: Extracorporeal life support can lead to rapid reversal of hypoxemia but the benefits and harms of different oxygenation targets in severely ill patients are unclear. Our primary objective was to investigate the association betw…
View article: Post-ligation cardiac syndrome after surgical versus transcatheter closure of patent ductus arteriosus in low body weight premature infants: a multicenter retrospective cohort study
Post-ligation cardiac syndrome after surgical versus transcatheter closure of patent ductus arteriosus in low body weight premature infants: a multicenter retrospective cohort study Open
View article: Compléments de préparations pour nourrisson à base de lait de vache chez les nourrissons allaités au sein et prévention primaire de l’allergie aux protéines du lait de vache : avis du Comité de nutrition de la Société française de pédiatrie
Compléments de préparations pour nourrisson à base de lait de vache chez les nourrissons allaités au sein et prévention primaire de l’allergie aux protéines du lait de vache : avis du Comité de nutrition de la Société française de pédiatrie Open
View article: High Amino Acid Intake in Early Life Is Associated With Systolic but Not Diastolic Arterial Hypertension at 5 Years of Age in Children Born Very Preterm
High Amino Acid Intake in Early Life Is Associated With Systolic but Not Diastolic Arterial Hypertension at 5 Years of Age in Children Born Very Preterm Open
Background The life course of individuals born very premature is a topic of increasing concern. The association between high early amino acid intake and later high blood pressure (HBP) in preterm neonates is debated. Methods and Results In…
View article: Post-ligation cardiac syndrome after surgical versustranscatheter closure of patent ductus arteriosus inlow body weight premature infants: a multicenterretrospective cohort study
Post-ligation cardiac syndrome after surgical versustranscatheter closure of patent ductus arteriosus inlow body weight premature infants: a multicenterretrospective cohort study Open
View article: Post-ligation cardiac syndrome after surgical versus transcatheter closure of patent ductus arteriosus in low body weight premature infants: a multicenter retrospective cohort study
Post-ligation cardiac syndrome after surgical versus transcatheter closure of patent ductus arteriosus in low body weight premature infants: a multicenter retrospective cohort study Open
Purpose Transcatheter patent ductus arteriosus (PDA) closure is a safe and effective alternative to surgical ligation in low-body-weight infants. Post-ligation cardiac syndrome (PLCS) is defined as severe hemodynamic and respiratory collap…
View article: Prophylactic Intravenous Acetaminophen in Extremely Premature Infants: Minimum Effective Dose Research by Bayesian Approach
Prophylactic Intravenous Acetaminophen in Extremely Premature Infants: Minimum Effective Dose Research by Bayesian Approach Open
View article: Tocolysis after preterm prelabor rupture of membranes and 5-year outcomes: a population-based cohort study
Tocolysis after preterm prelabor rupture of membranes and 5-year outcomes: a population-based cohort study Open
There was no difference in the neurodevelopmental outcomes at age 5.5 years among children with and without antenatal exposure to tocolysis after preterm prelabor rupture of membranes. To date, the health benefits of tocolytics remain unpr…
View article: Occurrence of Neonatal Necrotizing Enterocolitis in Premature Neonates and Gut Microbiota: A Case–Control Prospective Multicenter Study
Occurrence of Neonatal Necrotizing Enterocolitis in Premature Neonates and Gut Microbiota: A Case–Control Prospective Multicenter Study Open
Background: Necrotizing enterocolitis (NEC) is still one of the leading causes of neonatal death. The present study reports the data from a French case–control prospective multicenter study. Methods: A total of 146 preterm neonates (PNs) w…
View article: Association between gut microbiota at 3.5 years of age and body mass index at 5 years: Results from two French nationwide birth cohorts
Association between gut microbiota at 3.5 years of age and body mass index at 5 years: Results from two French nationwide birth cohorts Open
Background/Objectives: The relations between the gut microbiota and change in body mass index (BMI) or pediatric overweight in early life remain unclear and there is a scarcity of information regarding the preterm population. This study ai…
View article: Cognitive Training for Visuospatial Processing in Children Aged 5½ to 6 Years Born Very Preterm With Working Memory Dysfunction
Cognitive Training for Visuospatial Processing in Children Aged 5½ to 6 Years Born Very Preterm With Working Memory Dysfunction Open
Importance Compared with term-born peers, children born very preterm generally perform poorly in executive functions, particularly in working memory and inhibition. By taking advantage of neuroplasticity, computerized cognitive training of…
View article: High amino-acid intake in early life is associated with systolic but not diastolic arterial hypertension at 5-years of age in children born very preterm
High amino-acid intake in early life is associated with systolic but not diastolic arterial hypertension at 5-years of age in children born very preterm Open
BACKGROUND The life course of individuals born very premature is a topic of increasing concern as their neonatal survival has dramatically increased. In a national, prospective, population-based birth cohort, EPIPAGE-2, we observed that am…
View article: Pulmonary hypertension among preterm infants born at 22 through 32 weeks gestation in France: Prevalence, survival, morbidity and management in the EPIPAGE-2 cohort study
Pulmonary hypertension among preterm infants born at 22 through 32 weeks gestation in France: Prevalence, survival, morbidity and management in the EPIPAGE-2 cohort study Open
In this population-based cohort of very preterm infants, the prevalence of PH was 6 %. PH was associated with a significant decrease of survival without severe morbidity in this population.
View article: Assessing of executive functions in daily life in preterm children aged 3–4 years old from the “Behavior Rating Inventory of Executive Function—Preschool version” questionnaire
Assessing of executive functions in daily life in preterm children aged 3–4 years old from the “Behavior Rating Inventory of Executive Function—Preschool version” questionnaire Open
Background Executive functions (EFs) are a set of neuropsychological skills permitting solving problems in a new situation by regulating action, behavior, and emotional response. As cerebral maturation remains vulnerable in preterm childre…
View article: Assessing Behavioral Disorders with SDQ in Very Preterm Children at 5 Years of Age in LIFT Cohort
Assessing Behavioral Disorders with SDQ in Very Preterm Children at 5 Years of Age in LIFT Cohort Open
Background: Preterm-born children are at risk of behavioral disorders and the systematic assessment of these disorders remains a challenge. Questions remain about the accuracy of self-reported parent questionnaires and the real everyday li…
View article: Assisted reproductive techniques do not impact late neurodevelopmental outcomes of preterm children
Assisted reproductive techniques do not impact late neurodevelopmental outcomes of preterm children Open
Objective Assisted reproductive technology (ART) increases the rate of preterm births, though few studies have analyzed outcomes for these infants. No data are available on 4-year-old children born prematurely after ART. The objective was …
View article: Excessive workload and insufficient night‐shift remuneration are key elements of dissatisfaction at work for French neonatologists
Excessive workload and insufficient night‐shift remuneration are key elements of dissatisfaction at work for French neonatologists Open
Aim Neonatologists are exposed to ethical issues and unplanned emergencies that require 24‐h in‐house coverage. These elements may affect quality of life at work, which we surveyed. Methods This was a self‐administered, voluntary and anony…