Explanipedia

The Prevalence of Sexsomnia in a General Population Sample Open

Ståle Pallesen, Ingvild West Saxvig, Siri Waage, Carlos H. Schenck, Bjørn Bjorvatn · 2025

Few studies have surveyed the prevalence of sexsomnia and sexsomnic behaviors in general population samples. In the present study, 1002 respondents (508 males and 494 females), mean age 50.3 years (SD = 17.5), recruited from a Norwegian su…

Structural and Semantic Speech Graph Analysis of Dream Reports in Congenitally and Late Blind Individuals Open

Kausar Raheel, Nazanin Biabani, Olga Ivanenko, Qi Rui See, Rita Bertani , et al. · 2025

Background: Visual input is thought to influence spatial cognition and language. While blind individuals often rely on egocentric spatial representations, it remains unclear whether and how visual deprivation affects dream-related language…

Rapid eye movement sleep without atonia in patients with sleep-related fronto-temporal epilepsy Open

Gülçin Benbir Şenel, Rümeysa Unkun, Derya Karadeniz, Carlos H. Schenck · 2025

Background Interictal epileptiform discharges (IEDs) increase during non-rapid eye movement (NREM) sleep, and decrease or disappear in REM sleep, especially during phasic REM sleep. REM sleep without atonia (RSWA), and its possible effects…

0893 Expert Annotation of Free-text Descriptions of Dream Enactment Behaviors Associated with REM Sleep Behavior Disorder Open

Melissa B. Jones, Arash Maghsoudi, Taryn White, Amir Sharafkhaneh, Javad Razjouyan , et al. · 2025

Introduction We developed a database of free-text descriptions of dream enactment behavior (DEBs) from unstructured clinical notes of Veterans with electronic diagnoses of rapid eye movement sleep behavior disorder (RBD). We additionally e…

Conscious experiences during non-rapid eye movement sleep parasomnias Open

Anna Castelnovo, Francesca Siclari, Sara Spaggiari, Dolores Borth, Mauro Manconi , et al. · 2024

Disorders of Arousal (DOA) are non-rapid eye movement (NREM) parasomnias traditionally regarded as unconscious states. However, recent research challenges this assumption. This narrative review aims to explore the presence and qualitative …

IGLON5 Frequency in Idiopathic REM Sleep Behavior Disorder Open

Ronald B. Postuma, Nisa Vorasoot, Erik K. St. Louis, Amélie Pelletier, Miranda M. Lim , et al. · 2024

NCT03623672.

A case of accidental self-enucleation caused by obstructive sleep apnea Open

Nataliia Baker, Carlos H. Schenck, Erin C. Golden, Ranji Varghese · 2024

Two Cases of Sleep-related Dissociative Disorder with Episodes of Nocturnal Eating Open

Carlos H. Schenck · 2024

Sleep-related dissociative disorder (SRDD) is a female-predominant psychiatric parasomnia that was first identified as a condition that mimics sleepwalking in 1989, and was included in the International Classification of Sleep Disorders, 2…

Validation of electronic diagnostic codes for rapid eye movement sleep behavior disorder Open

Melissa B. Jones, Carlos H. Schenck, Mehrnaz Azarian, Ricardo E. Jorge, Amir Sharafkhaneh , et al. · 2024

Polysomnographic features associated with clonazepam and melatonin treatment in isolated <span>REM</span> sleep behavior disorder: Time for new therapeutic approaches? Open

Maria P. Mogavero, Raffaele Ferri, Sara Marelli, Giuseppe Lanza, Michele Terzaghi , et al. · 2024

Aims Although clonazepam (CLO) and melatonin (MLT) are the most frequently used treatments for REM sleep behavior disorder, the polysomnographic features associated with their use are little known. The aim of this study was to evaluate pol…

Comorbid neurotrauma increases neurodegenerative-relevant cognitive, motor, and autonomic dysfunction in patients with rapid eye movement sleep behavior disorder: a substudy of the North American Prodromal Synucleinopathy Consortium Open

Jonathan E. Elliott, Brittany R. Ligman, Mohini Bryant‐Ekstrand, Allison Keil, Katherine Powers , et al. · 2024

Study Objectives Rapid eye movement sleep behavior disorder (RBD) is strongly associated with phenoconversion to an overt synucleinopathy, e.g. Parkinson’s disease (PD), Lewy body dementia, and related disorders. Comorbid traumatic brain i…

Validation of the RBD Symptom Severity Scale in the North American Prodromal Synucleinopathy Consortium Open

Parichita Choudhury, Joyce Lee‐Iannotti, Andrea Busicescu, Pooja Rangan, Maria Livia Fantini , et al. · 2024

We describe the RBDSSS with adequate psychometric and clinimetric properties to quantify RBD symptom severity and good concordance between participant and bedpartner questionnaires and between RBDSSS scores and clinician-assessed global se…

Estratificación del riesgo de fenoconversión al parkinsonismo en pacientes con trastorno de conducta del sueño REM aislado. Estudio de seguimiento en un centro de Turquía Open

Gulcin Benbir-Senel, N. Albayrak, I. Yanik, E Gokcen-Polat, Carlos H. Schenck , et al. · 2024

It is of great importance to have a world-wide perspective of phenoconversion rates from iRBD to overt neurodegeneration, since racial and geographical factors may play important modifying roles. Relatively younger age and shorter disease …

The lasting legacy of Charles Fisher (1908–1988), pioneering sleep laboratory scientist and sleep medicine psychiatrist Open

Carlos H. Schenck, Federica Provini, Alan S. Eiser · 2024

Charles Fisher is a pioneering historical figure in sleep laboratory research and sleep medicine who distinguished himself in nine areas: (1) he first documented nocturnal sleep-onset rapid eye movement (REM) sleep periods in narcoleptic p…

REM sleep behavior disorder: update on diagnosis and management Open

Manoel Alves Sobreira-Neto, Fernando Gustavo Stelzer, Lívia Leite Góes Gitaí, Rosana Alves, Álan Luiz Éckeli , et al. · 2023

REM sleep behavior disorder (RBD) is characterized by a loss of atonia of skeletal muscles during REM sleep, associated with acting out behaviors during dreams. Knowledge of this pathology is important to predict neurodegenerative diseases…

A Retrospective Pilot Study of Imagery Rehearsal Therapy Enhanced with Narrative Therapy Principles for the Treatment of Nightmares in US Military Veterans Open

Ann Marie Wagner, Anne Richards, Christine E. Chiros, Paul Thuras, Elizabeth C. Parsons , et al. · 2023

Introduction Chronic nightmares are a common and disabling feature of posttraumatic stress disorder (PTSD) for which broadly effective treatments are still lacking. While imagery rehearsal therapy (IRT) demonstrates benefits for patients w…

Frequency of Orthostatic Hypotension in Isolated REM Sleep Behavior Disorder Open

Jonathan E. Elliott, Mohini Bryant‐Ekstrand, Allison Keil, Brittany R. Ligman, Miranda M. Lim , et al. · 2023

ClinicalTrials.gov: NCT03623672; North American Prodromal Synucleinopathy Consortium.

102 Improved Care for Survivors of Sexual Assault With an Electronic Health Record-Integrated Clinical Pathway Open

David Yang, Raphael Sherak, Carlos H. Schenck, Marek Gawel, A. Cordone , et al. · 2023

Update on Rapid-Eye-Movement Sleep Behavior Disorder (RBD): Focus on Its Strong Association with α-Synucleinopathies Open

Carlos H. Schenck · 2023

REM sleep behavior disorder (RBD) is a parasomnia in which the customary generalized skeletal muscle atonia of REM sleep, “REM-atonia”, is compromised, allowing for the injurious acting-out of dreams. RBD can be idiopathic/isolated (iRBD) …

A challenging case of sexsomnia in an adolescent female presenting with depressive-like symptoms Open

João Brás, Carlos H. Schenck, Rui Andrade, A. P. da Costa, Carlos Teixeira , et al. · 2023

Awake or Sleeping? Maybe Both… A Review of Sleep-Related Dissociative States Open

Maria Eduarda Japyassu Sodré, Isabel Wießner, Muna Irfan, Carlos H. Schenck, Sérgio Mota‐Rolim · 2023

Recent studies have begun to understand sleep not only as a whole-brain process but also as a complex local phenomenon controlled by specific neurotransmitters that act in different neural networks, which is called “local sleep”. Moreover,…

Quantitative measurement of motor activity during sleep in isolated REM sleep behavior disorder patients using actigraphy before and after treatment with clonazepam Open

K. S. Park, Yong Woo Shin, Sungeun Hwang, El Jeong, Tae‐Joon Kim , et al. · 2023

Study Objectives We conducted a prospective study to quantify motor activity during sleep measured by actigraphy before and after 3 months of treatment with clonazepam in patients with video-polysomnography (vPSG) confirmed isolated rapid …

0983 Hand Dominance in Sexsomnia: A Clue to Pathophysiology? Open

V. Badami, Alon Y. Avidan, Carlos H. Schenck · 2023

Introduction Sexsomnia is a variant of confusional arousal, a NREM parasomnia (NREMP), typically consisting of sexual behaviors manifesting upon partial arousal from deep NREM sleep; however, its pathophysiology is not well understood, and…

0700 Parasomnia-related homicides: A systematic review and a critical analysis of the medical literature Open

Anna Castelnovo, Matthias Schraemli, Carlos H. Schenck, Mauro Manconi · 2023

Introduction Cases of homicide allegedly committed during sleep have been described since ancient history. The strongest link between violence and sleep disorders is represented by the so-called parasomnias, a group of sleep disorders char…

0704 A PSG Study of the Effect of Clonazepam and Melatonin on REM Sleep without Atonia in Isolated REM Sleep Behavior Disorder Open

Maria P. Mogavero, Raffaele Ferri, Sara Marelli, Alessandra Castelnuovo, Giuseppe Lanza , et al. · 2023

Introduction Although very few prospective clinical trials are available assessing the benefits of drugs in isolated REM sleep behavior disorder (iRBD), clonazepam and melatonin are considered as the first-line treatment options. However, …

Frequency of antidepressant use and clinical characteristics of children and adolescents undergoing polysomnography: an observational study Open

Lourdes M. DelRosso, Oliviero Bruni, Maria P. Mogavero, Amy Fickensher, Carlos H. Schenck , et al. · 2023

Background Antidepressants are increasingly used in children for various psychiatric disorders but also for sleep disorders such as insomnia; however, it is currently unknown how many children undergoing polysomnography (PSG) are taking an…

Baseline characteristics of the North American prodromal Synucleinopathy cohort Open

Jonathan E. Elliott, Miranda M. Lim, Allison Keil, Ronald B. Postuma, Amélie Pelletier , et al. · 2023

Objective Rapid eye movement (REM) sleep behavior disorder (RBD) is widely considered a prodromal synucleinopathy, as most with RBD develop overt synucleinopathy within ~10 years. Accordingly, RBD offers an opportunity to test potential tr…

The polysomnographic diagnosis of REM sleep behavior disorder: to change or not to change, that is the question Open

Raffaele Ferri, Simon J.G. Lewis, Valérie Cochen De Cock, Naoko Tachibana, Clete A. Kushida , et al. · 2022

Journal Article The polysomnographic diagnosis of REM sleep behavior disorder: to change or not to change, that is the question Get access Raffaele Ferri, Raffaele Ferri Department of Neurology I.C., Sleep Research Centre, Oasi Research In…

Effects of bupropion and SSRI antidepressants on leg movement activity and chin muscle tone during sleep in adolescents Open

Lourdes M. DelRosso, Maria P. Mogavero, Amy Fickensher, Oliviero Bruni, Carlos H. Schenck , et al. · 2022

Emotional and Environmental Factors Aggravating Dream Enactment Behaviors in Patients with Isolated REM Sleep Behavior Disorder Open

Jin‐Sun Jun, Jun‐Sang Sunwoo, Jung‐Ick Byun, Jung-Won Shin, Tae‐Joon Kim , et al. · 2022

Our results suggest that DEBs in iRBD patients may be mainly aggravated by emotional factors. These negative effects appeared to be more prominent in female and depressed patients.

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