Christopher Teale
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View article: Diversity of antimicrobial resistance and virulence genes of pathogenic Escherichia coli recovered from pigs in England
Diversity of antimicrobial resistance and virulence genes of pathogenic Escherichia coli recovered from pigs in England Open
Introduction We characterised the genomes of 208 pathogenic Escherichia coli isolated from pigs diagnosed with enteric colibacillosis (EC), bowel oedema (BO) or colisepticaemia (CS) in England between 2016–2020 to investigate their antimic…
View article: Azithromycin resistance in <i>Escherichia coli</i> and <i>Salmonella</i> from food-producing animals and meat in Europe
Azithromycin resistance in <i>Escherichia coli</i> and <i>Salmonella</i> from food-producing animals and meat in Europe Open
Objectives To characterize the genetic basis of azithromycin resistance in Escherichia coli and Salmonella collected within the EU harmonized antimicrobial resistance (AMR) surveillance programme in 2014–18 and the Danish AMR surveillance …
View article: Occurrence and characterization of <i>rmtB</i>-harbouring <i>Salmonella</i> and <i>Escherichia coli</i> isolates from a pig farm in the UK
Occurrence and characterization of <i>rmtB</i>-harbouring <i>Salmonella</i> and <i>Escherichia coli</i> isolates from a pig farm in the UK Open
Objectives To characterize and elucidate the spread of amikacin-resistant Enterobacteriaceae isolates from environmental samples on a pig farm in the UK, following the previous identification of index Salmonella isolates harbouring the rmt…
Geographical and temporal distribution of multidrug-resistant Salmonella Infantis in Europe and the Americas Open
Recently emerged S. Infantis strains carrying resistance to several commonly used antimicrobials have been reported from different parts of the globe, causing human cases of salmonellosis and with occurrence reported predominantly in broil…
The use of aminopenicillins in animals within the EU, emergence of resistance in bacteria of animal and human origin and its possible impact on animal and human health Open
Aminopenicillins have been widely used for decades for the treatment of various infections in animals and humans in European countries. Following this extensive use, acquired resistance has emerged among human and animal pathogens and comm…
Detection of the transferable tigecycline resistance gene <i>tet</i>(X4) in <i>Escherichia coli</i> from pigs in the United Kingdom Open
Tigecycline is one of the last-resort critically important antimicrobials and is used to treat MDR bacterial infections.1 The first report of transferable tigecycline resistance, mediated by newly reported tet(X3) and tet(X4) genes, in bac…
A proposed scheme for the monitoring of antibiotic resistance in veterinary pathogens of food animals in the UK Open
Background : Antibiotic resistance in bacteria is a global threat to both animal and public health, and detecting its occurrence is an important component of control strategies. Monitoring programmes for antibiotic resistance are currently…
The importance of using whole genome sequencing and extended spectrum beta-lactamase selective media when monitoring antimicrobial resistance Open
To tackle the problem of antimicrobial resistance (AMR) surveillance programmes are in place within Europe applying phenotypic methods, but there are plans for implementing whole genome sequencing (WGS). We tested the benefits of WGS using…
The O-Antigen Epitope Governs Susceptibility to Colistin in Salmonella enterica Open
Some serovars of Salmonella , namely, those belonging to group D, appear to show a degree of intrinsic resistance to colistin. This observed intrinsic colistin resistance is of concern since this last-resort drug might no longer be effecti…
Extended-spectrum β-lactamase-producing Escherichia coli in human-derived and foodchain-derived samples from England, Wales, and Scotland: an epidemiological surveillance and typing study Open
NIHR Policy Research.
Technical specifications on harmonised monitoring of antimicrobial resistance in zoonotic and indicator bacteria from food‐producing animals and food Open
Proposals to update the harmonised monitoring and reporting of antimicrobial resistance (AMR) from a public health perspective in Salmonella, Campylobacter coli, Campylobacter jejuni, Escherichia coli, Enterococcus faecalis, Enterococcus f…
Identification of a New Antimicrobial Resistance Gene Provides Fresh Insights Into Pleuromutilin Resistance in Brachyspira hyodysenteriae, Aetiological Agent of Swine Dysentery Open
Brachyspira hyodysenteriae is the aetiological agent of swine dysentery, a globally distributed disease that causes profound economic loss, impedes the free trade and movement of animals, and has significant impact on pig health. Infection…
View article: Comparative genomics of quinolone‐resistant and susceptible Campylobacter jejuni of poultry origin from major poultry producing European countries (GENCAMP)
Comparative genomics of quinolone‐resistant and susceptible Campylobacter jejuni of poultry origin from major poultry producing European countries (GENCAMP) Open
A total of 502 Campylobacter jejuni isolates from poultry in 12 different European countries (10 of them the largest poultry production countries in Europe) were whole genome sequenced to examine the genomic diversity of fluoroquinolone re…
Comparison of Automated Antimicrobial Susceptibility Testing Systems To Detect <i>mecC</i> -Positive Methicillin-Resistant Staphylococcus aureus Open
International audience
View article: mcr-1 and mcr-2 (mcr-6.1) variant genes identified in Moraxella species isolated from pigs in Great Britain from 2014 to 2015
mcr-1 and mcr-2 (mcr-6.1) variant genes identified in Moraxella species isolated from pigs in Great Britain from 2014 to 2015 Open
Our results add further evidence for the mobilization of the mcr-pap2 unit from Moraxella via composite transposons leading to its global dissemination. The presence of mcr-pap2 from recent Moraxella isolates indicates they may comprise a …
Detection of <i>mecC</i> -Positive Staphylococcus aureus: What To Expect from Immunological Tests Targeting PBP2a? Open
International audience
Livestock-Associated Methicillin Resistant Staphylococcus aureus (LA-MRSA) Clonal Complex (CC) 398 Isolated from UK Animals belong to European Lineages Open
In recent years, there has been an increase in the number of livestock-associated methicillin resistant Staphylococcus aureus (LA-MRSA) clonal complex (CC) 398 recovered from S. aureus isolated animals in the UK. To determine possible orig…
Public health risk of antimicrobial resistance transfer from companion animals Open
Antimicrobials are important tools for the therapy of infectious bacterial diseases in companion animals. Loss of efficacy of antimicrobial substances can seriously compromise animal health and welfare. A need for the development of new an…
Colistin resistance in<i>Salmonella</i>and<i>Escherichia coli</i>isolates from a pig farm in Great Britain Open
Identification of the mcr-1 gene in Enterobacteriaceae from pigs confirms its presence in livestock in Great Britain. The results suggest dissemination of resistance through different horizontally transferable elements. The in vitro transf…