Yun‐Chul Hong
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View article: Molecular classification and outcomes in pediatric aplastic anemia with myeloid neoplasm-associated gene variants
Molecular classification and outcomes in pediatric aplastic anemia with myeloid neoplasm-associated gene variants Open
Background The genetic variations in aplastic anemia (AA) patients are closely related to clonal hematopoiesis, but there is limited research on this topic in children with AA. The aim of this study is to investigate the molecular classifi…
View article: Prenatal exposure to heavy metals and the trajectory of autistic traits in childhood
Prenatal exposure to heavy metals and the trajectory of autistic traits in childhood Open
This is the first study to link prenatal heavy-metal exposure with autistic trait trajectories. Prenatal lead exposure showed consistent associations across multiple childhood stages in girls, highlighting the need to reduce prenatal expos…
View article: Ischemic heart disease mortality due to fine particulate matter in Seoul between 2016 and 2020
Ischemic heart disease mortality due to fine particulate matter in Seoul between 2016 and 2020 Open
View article: Temperature effect on scrub typhus incidence in South Korea: the projection for climate change
Temperature effect on scrub typhus incidence in South Korea: the projection for climate change Open
Objective The influence of climate change on infectious disease dynamics is a subject of interest, but it demands robust scientific evidence. This study explores the short-term and long-term relationships between meteorological factors and…
View article: Differential Effects of Green Space Typologies on Congenital Anomalies: Data from the Korean National Health Insurance Service (2008–2013)
Differential Effects of Green Space Typologies on Congenital Anomalies: Data from the Korean National Health Insurance Service (2008–2013) Open
Background/Objectives: Urban green space has been increasingly recognized as a determinant of maternal and child health. This study investigated the association between prenatal exposure to different types of green space and the risk of co…
View article: Mortality burden attributable to long-term exposure to fine particulate matter among older adults in Korea
Mortality burden attributable to long-term exposure to fine particulate matter among older adults in Korea Open
OBJECTIVES: This study aimed to evaluate the association between long-term exposure to particulate matter with an aerodynamic diameter <2.5 μm (PM2.5) and cause-specific mortality among older adults in Korea, providing insights …
View article: Sex-specific effects of prenatal exposure to phthalates and bisphenol A on adverse birth outcomes: Results from The Korean CHildren’s ENvironmental health Study (Ko-CHENS)
Sex-specific effects of prenatal exposure to phthalates and bisphenol A on adverse birth outcomes: Results from The Korean CHildren’s ENvironmental health Study (Ko-CHENS) Open
This study suggests a potential association between exposure to BPA during early pregnancy and PTB, while exposure to MCOP during late pregnancy was associated with increased PTB risk in male infants.
View article: Association of Maternal Exposure to Fine Particulate Matter During Pregnancy with Anterior Segment Dysgenesis Risk: A Matched Case-Control Study
Association of Maternal Exposure to Fine Particulate Matter During Pregnancy with Anterior Segment Dysgenesis Risk: A Matched Case-Control Study Open
Background/Objectives: To assess the association of residential-level maternal particulate matter of 2.5 μm diameter or less (PM2.5) exposure during pregnancy with anterior segment dysgenesis (ASD) risk. Methods: This study used data from …
View article: Environmental disease monitoring by regional Environmental Health Centers in Korea: a narrative review
Environmental disease monitoring by regional Environmental Health Centers in Korea: a narrative review Open
This study explores the development, roles, and key initiatives of the Regional Environmental Health Centers in Korea, detailing their evolution through four distinct phases and their impact on environmental health policy and local governa…
View article: Corrigendum to “Ambient particulate matter and surrounding greenness in relation to sleep quality among pregnant women: A nationwide cohort study” [Heliyon 10 (5) (March 2024) e26742]
Corrigendum to “Ambient particulate matter and surrounding greenness in relation to sleep quality among pregnant women: A nationwide cohort study” [Heliyon 10 (5) (March 2024) e26742] Open
[This corrects the article DOI: 10.1016/j.heliyon.2024.e26742.].
View article: Long-term ozone exposure and metabolic syndrome in Korea: Evidence from the Korea National Health and Nutrition Examination Survey 2007–2022
Long-term ozone exposure and metabolic syndrome in Korea: Evidence from the Korea National Health and Nutrition Examination Survey 2007–2022 Open
View article: Paraben Mixture Exposure and Liver Function in Pregnant Women: Findings from the Korean CHildren’s ENvironmental health Study (Ko-CHENS)
Paraben Mixture Exposure and Liver Function in Pregnant Women: Findings from the Korean CHildren’s ENvironmental health Study (Ko-CHENS) Open
View article: A New Approach for Biological Age Assessment and Trajectory of Age Acceleration
A New Approach for Biological Age Assessment and Trajectory of Age Acceleration Open
View article: A Systematic Review and Meta-Analysis on Long-Term Exposure to Particulate Matter and All-Cause and Cause-Specific Mortality in the Asia-Pacific States
A Systematic Review and Meta-Analysis on Long-Term Exposure to Particulate Matter and All-Cause and Cause-Specific Mortality in the Asia-Pacific States Open
PROSPERO Identifier: CRD42023441916.
View article: Long-Term Ozone Exposure, COPD, and Asthma Mortality: A Retrospective Cohort Study in the Republic of Korea
Long-Term Ozone Exposure, COPD, and Asthma Mortality: A Retrospective Cohort Study in the Republic of Korea Open
Ozone concentrations have increased in recent decades, and several studies have reported that long-term exposure to ozone increases the mortality risk induced by respiratory conditions. However, research on cause-specific mortality related…
View article: Adequacy of the physician workforce for preparing for future society in Korea: an English translation
Adequacy of the physician workforce for preparing for future society in Korea: an English translation Open
Objectives: This study aimed to assess whether the current physician workforce in Korea is sufficient to meet future healthcare demands, considering demographic changes and increasing medical needs. The objective was to project the future …
View article: Prenatal and early-life air pollutant exposure and epigenetic aging acceleration
Prenatal and early-life air pollutant exposure and epigenetic aging acceleration Open
We found that prenatal and childhood exposure to ambient air pollutants is associated with EAA among children. The results suggest that air pollution could induce excess biological aging even in prenatal and early life.
View article: The implications of social relationships for depressive symptoms in community-dwelling older adults: Results from the Korea Community Health Survey
The implications of social relationships for depressive symptoms in community-dwelling older adults: Results from the Korea Community Health Survey Open
Background Epidemiological findings have established a strong link between social relationships and mental health in older populations. However, a comprehensive exploration within diverse social contexts is warranted. This study aimed to i…
View article: Mortality Burden Due to Short-term Exposure to Fine Particulate Matter in Korea
Mortality Burden Due to Short-term Exposure to Fine Particulate Matter in Korea Open
Objectives: Excess mortality associated with long-term exposure to fine particulate matter (PM2.5) has been documented. However, research on the disease burden following short-term exposure is scarce. We investigated the cause-s…
View article: Supplementary Table S2 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies
Supplementary Table S2 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies Open
Supplementary Table S2 shows the signals at known susceptibility loci from ever- and never-smoking lung cancer.
View article: Relationship of bisphenol A substitutes bisphenol F and bisphenol S with adiponectin/leptin ratio among children from the environment and development of children cohort
Relationship of bisphenol A substitutes bisphenol F and bisphenol S with adiponectin/leptin ratio among children from the environment and development of children cohort Open
Increased exposure to BPS and BPF is associated with higher fat mass and leptin concentration, lower serum adiponectin, and lower A/L ratio in children. These findings suggest potential adverse effects of BPA substitutes on adiposity and a…
View article: Figure S3 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies
Figure S3 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies Open
Supplementary Figure S3 displays the Validation of the association effect of rs6757077 at IKZF2 using data from six independent study sites in China.
View article: Supplementary Table S1 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies
Supplementary Table S1 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies Open
Supplementary Table S1 displays the number of ever- and never-smokers from each of the ten studies.
View article: Figure S1 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies
Figure S1 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies Open
Supplementary Figure S1 displays the distribution of histology subtypes in each population in ever- and never-smokers.
View article: Supplementary Table S6 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies
Supplementary Table S6 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies Open
Supplementary Table S6 displays epigenomic evidence for the variants being located within genomic regions associated with regulatory activity.
View article: Supplementary Table S5 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies
Supplementary Table S5 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies Open
Supplementary Table S5 shows the signals for the variants in stratified analysis by smoking behavior
View article: Figure S4 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies
Figure S4 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies Open
Supplementary Figure S4 shows the results of eQTL analysis of rs968516 in GTEx.
View article: Figure S2 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies
Figure S2 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies Open
Supplementary Figure S2 shows the bar chart of lung cancer risk across different smoking strata in EUR, EAS and AFR.
View article: Supplementary Table S1 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies
Supplementary Table S1 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies Open
Supplementary Table S1 displays the number of ever- and never-smokers from each of the ten studies.
View article: Figure S2 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies
Figure S2 from Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies Open
Supplementary Figure S2 shows the bar chart of lung cancer risk across different smoking strata in EUR, EAS and AFR.