Caineng Cao
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View article: Optimal post-treatment surveillance strategy for human papillomavirus-positive oropharyngeal cancer
Optimal post-treatment surveillance strategy for human papillomavirus-positive oropharyngeal cancer Open
The objective of the current study was to determine the optimal individualized surveillance strategies for human papillomavirus (HPV)-positive oropharyngeal cancer. A consecutive cohort of 1,146 HPV-positive oropharyngeal cancer patients t…
View article: LncRNA GAS5 Regulates Myometrial Cell Contractions in an m6A-Dependent Manner
LncRNA GAS5 Regulates Myometrial Cell Contractions in an m6A-Dependent Manner Open
LncRNAs are engaged in signaling pathways in human physiological and pathological states. However, LncRNAs mediate the onset of human labor still remains unknown. RNA sequencing of lower segment myometrium (in labor vs. not in labor) was a…
View article: Ninth Version of the AJCC and UICC Nasopharyngeal Cancer TNM Staging Classification
Ninth Version of the AJCC and UICC Nasopharyngeal Cancer TNM Staging Classification Open
Importance Accurate staging is a fundamental step in treating patients with nasopharyngeal carcinoma (NPC) worldwide; this is crucial not only for prognostication, but also for guiding treatment decisions. The American Joint Committee on C…
View article: Does Fever Caused by the COVID‐19 Virus Before Labor Increase the Rate of MSAF and Affect Maternal and Fetal Outcomes?
Does Fever Caused by the COVID‐19 Virus Before Labor Increase the Rate of MSAF and Affect Maternal and Fetal Outcomes? Open
Objective: The main objective of this study is to investigate whether there is a difference in the occurrence of MSAF between fever and nonfever–pregnant women during the COVID‐19 pandemic. Study Design: We conducted a multicenter retrospe…
View article: Quality of life and Its Association With Radiation-Induced Oral Mucositis in Patients With Nasopharyngeal Carcinoma During Radiotherapy: A Prospective Study
Quality of life and Its Association With Radiation-Induced Oral Mucositis in Patients With Nasopharyngeal Carcinoma During Radiotherapy: A Prospective Study Open
We aimed to investigate the quality of life of nasopharyngeal carcinoma (NPC) patients during treatment and association with radiation-induced oral mucositis (ROM). A prospective study of 173 patients with nasopharyngeal carcinoma was init…
View article: Locoregional Extension Patterns of Nasopharyngeal Carcinoma Detected by FDG PET/MR
Locoregional Extension Patterns of Nasopharyngeal Carcinoma Detected by FDG PET/MR Open
Purpose We sought to define the locoregional extension patterns of nasopharyngeal carcinomas (NPCs) by positron emission tomography (PET)/magnetic resonance imaging (MRI) and to improve clinical target volume (CTV) delineation. Methods Bet…
View article: Nutritional Status and Its Association With Radiation-Induced Oral Mucositis in Patients With Nasopharyngeal Carcinoma During Radiotherapy: A Prospective Study
Nutritional Status and Its Association With Radiation-Induced Oral Mucositis in Patients With Nasopharyngeal Carcinoma During Radiotherapy: A Prospective Study Open
Malnutrition occurred early in NPC patients and worsened continuously during RT. ROM was strongly associated with nutritional status. Nutritional support should be provided at the start of RT, especially in patients at high-risk of severe …
View article: Adding Concurrent Chemotherapy to Intensity-Modulated Radiotherapy Does Not Improve Treatment Outcomes for Stage II Nasopharyngeal Carcinoma: A Phase 2 Multicenter Clinical Trial
Adding Concurrent Chemotherapy to Intensity-Modulated Radiotherapy Does Not Improve Treatment Outcomes for Stage II Nasopharyngeal Carcinoma: A Phase 2 Multicenter Clinical Trial Open
Purpose: To explore the efficacy of concomitant chemotherapy in intensity-modulated radiotherapy (IMRT) to treat stage II nasopharyngeal carcinoma (NPC). Methods and Materials: In this randomized phase 2 study [registered with ClinicalTria…
View article: Prognostic Value and Staging Classification of Lymph Nodal Necrosis in Nasopharyngeal Carcinoma after Intensity-Modulated Radiotherapy
Prognostic Value and Staging Classification of Lymph Nodal Necrosis in Nasopharyngeal Carcinoma after Intensity-Modulated Radiotherapy Open
MRI-determined LNN is an independent negative prognostic factor for NPC. The proposed N classification system is powerfully predictive.
View article: Paranasal Sinus Invasion in Nasopharyngeal Carcinoma after Intensity-Modulated Radiotherapy
Paranasal Sinus Invasion in Nasopharyngeal Carcinoma after Intensity-Modulated Radiotherapy Open
MRI-determined paranasal sinus invasion is an independent prognostic factor of NPC treated by IMRT. Paranasal sinus invasion is recommended to classify as T4 classification in the 8th AJCC staging system for NPC.
View article: Cytomembranic PD-L1 expression in locoregionally advanced nasopharyngeal carcinoma
Cytomembranic PD-L1 expression in locoregionally advanced nasopharyngeal carcinoma Open
Linfeng Zheng,1,* Caineng Cao,2,3,* Guoping Cheng,1 Qiaoying Hu,2,3 Xiaozhong Chen2,3 1Department of Pathology, 2Department of Radiation Oncology, Zhejiang Cancer Hospital, Hangzhou, 3Zhejiang Key Laboratory of Radiation Oncology, Hangzhou…
View article: Primary breast lymphoma: A single center study
Primary breast lymphoma: A single center study Open
The aim of the present study was to summarize the clinical characteristics of primary breast lymphoma (PBL) and evaluate its management approaches. A total of 29 patients newly diagnosed with PBL, and treated between April 2006 and May 201…
View article: Chemotherapy combined with high-dose extended-field radiotherapy for stage I extranodal nasal-type natural killer/T-cell lymphoma
Chemotherapy combined with high-dose extended-field radiotherapy for stage I extranodal nasal-type natural killer/T-cell lymphoma Open
The doxorubicin-based CT combined with high-dose extended-field RT yielded promising outcomes for stage I extranodal nasal-type NKTCL, and CT was an independent factor for PFS.
View article: Primary breast diffuse large B-cell lymphoma in the era of rituximab
Primary breast diffuse large B-cell lymphoma in the era of rituximab Open
Primary breast DLBCL appears to be a rare disease. Adding rituximab might improve survival in patients with primary breast DLBCL. Further prospective studies are needed to evaluate the role of rituximab for primary breast DLBCL.
View article: Magnetic Resonance Imaging–Detected Intracranial Extension in the T4 Classification Nasopharyngeal Carcinoma with Intensity-Modulated Radiotherapy
Magnetic Resonance Imaging–Detected Intracranial Extension in the T4 Classification Nasopharyngeal Carcinoma with Intensity-Modulated Radiotherapy Open
For patients with T4 classification NPC, those with MRI-detected intracranial extension are more likely to experience local failure and death after IMRT than patients without intracranial extension. According to the site of invasion, subcl…
View article: Influence of body mass index on the long-term outcomes of patients with esophageal squamous cell carcinoma who underwent esophagectomy as a primary treatment
Influence of body mass index on the long-term outcomes of patients with esophageal squamous cell carcinoma who underwent esophagectomy as a primary treatment Open
We explored the influence of body mass index (BMI) on long-term outcomes in patients with esophageal squamous cell carcinoma (ESCC) who underwent esophagectomy as a primary treatment. BMI is a risk factor for development of esophageal canc…