Caleb A. Dawson YOU? Author Swipe

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BEHAV3D Tumor Profiler to map heterogeneous cancer cell behavior in the tumor microenvironment Open

Emilio Rios-Jimenez, Anoek Zomer, Raphaël Collot, Mario Barrera Román, Sandra F Archidona , et al. · 2025

Intravital microscopy (IVM) enables live imaging of animals at single-cell level, offering essential insights into cancer progression. This technique allows for the observation of single-cell behaviors within their natural 3D tissue enviro…

Author response: BEHAV3D Tumor Profiler to map heterogeneous cancer cell behavior in the tumor microenvironment Open

Emilio Rios-Jimenez, Anoek Zomer, Raphaël Collot, Mario Barrera Román, Sandra F Archidona , et al. · 2025

BEHAV3D Tumor Profiler to map heterogeneous cancer cell behavior in the tumor microenvironment Open

Emilio Rios-Jimenez, Anoek Zomer, Raphaël Collot, Mario Barrera Román, Sandra F Archidona , et al. · 2025

Intravital microscopy (IVM) enables live imaging of animals at single-cell level, offering essential insights into cancer progression. This technique allows for the observation of single-cell behaviors within their natural 3D tissue enviro…

Author response: BEHAV3D Tumor Profiler to map heterogeneous cancer cell behavior in the tumor microenvironment Open

Emilio Rios-Jimenez, Anoek Zomer, Raphaël Collot, Mario Barrera Román, Sandra F Archidona , et al. · 2025

BEHAV3D Tumor Profiler to map heterogeneous cancer cell behavior in the tumor microenvironment Open

Emilio Rios-Jimenez, Anoek Zomer, Raphaël Collot, Mario Barrera Román, Sandra F Archidona , et al. · 2025

Intravital microscopy (IVM) enables live imaging of animals at single-cell level, offering essential insights into cancer progression. This technique allows for the observation of single-cell behaviors within their natural 3D tissue enviro…

Author response: BEHAV3D Tumor Profiler to map heterogeneous cancer cell behavior in the tumor microenvironment Open

Emilio Rios-Jimenez, Anoek Zomer, Raphaël Collot, Mario Barrera Román, Sandra F Archidona , et al. · 2025

Hormone-responsive progenitors have a unique identity and exhibit high motility during mammary morphogenesis Open

Caleb A. Dawson, Michael J. G. Milevskiy, Bianca D. Capaldo, Raymond K. H. Yip, Xiaoyu Song , et al. · 2024

Hormone-receptor-positive (HR⁺) luminal cells largely mediate the response to estrogen and progesterone during mammary gland morphogenesis. However, there remains a lack of consensus on the precise nature of the precursor cells …

BEHAV3D Tumor Profiler to map heterogeneous cancer cell behavior in the tumor microenvironment Open

Emilio Rios-Jimenez, Anoek Zomer, Raphaël Collot, Mario Barrera Román, Sandra F Archidona , et al. · 2024

Intravital microscopy (IVM) enables live imaging of animals at single-cell level, offering essential insights into cancer progression. This technique allows for the observation of single-cell behaviors within their natural 3D tissue enviro…

The interweaved signatures of common-gamma-chain cytokines across immunologic lineages Open

Alev Baysoy, Kumba Seddu, Tamara Salloum, Caleb A. Dawson, Juliana J. Lee , et al. · 2023

“γc” cytokines are a family whose receptors share a “common-gamma-chain” signaling moiety, and play central roles in differentiation, homeostasis, and communications of all immunocyte lineages. As a resource to better understand their rang…

Langerhans cells are an essential cellular intermediary in chronic dermatitis Open

Holly Anderton, Michaël Chopin, Caleb A. Dawson, Stephen L. Nutt, Lachlan Whitehead , et al. · 2022

SHARPIN regulates signaling from the tumor necrosis factor (TNF) superfamily and pattern-recognition receptors. An inactivating Sharpin mutation in mice causes TNF-mediated dermatitis. Blocking cell death prevents the phenotype, implicatin…

<i>In vivo</i> genome‐editing screen identifies tumor suppressor genes that cooperate with <i>Trp53</i> loss during mammary tumorigenesis Open

Luuk Heitink, James R. Whittle, François Vaillant, Bianca D. Capaldo, Johanna F. Dekkers , et al. · 2022

Breast cancer is a heterogeneous disease that comprises multiple histological and molecular subtypes. To gain insight into mutations that drive breast tumorigenesis, we describe a pipeline for the identification and validation of tumor sup…

Author response for "In vivo genome‐editing screen identifies tumor suppressor genes that cooperate with Trp53 loss during mammary tumorigenesis" Open

Luuk Heitink, James R. Whittle, François Vaillant, Bianca D. Capaldo, Johanna F. Dekkers , et al. · 2021

Single cell transcriptome atlas of mouse mammary epithelial cells across development Open

Bhupinder Pal, Yunshun Chen, Michael J. G. Milevskiy, François Vaillant, Lexie Prokopuk , et al. · 2021

Membrane budding is a major mechanism of in vivo platelet biogenesis Open

Kathryn Potts, Alison Farley, Caleb A. Dawson, Joel S. Rimes, Christine Biben , et al. · 2020

How platelets are produced by megakaryocytes in vivo remains controversial despite more than a century of investigation. Megakaryocytes readily produce proplatelet structures in vitro; however, visualization of platelet release from propla…

Modeling Breast Cancer Using CRISPR-Cas9–Mediated Engineering of Human Breast Organoids Open

Johanna F. Dekkers, James R. Whittle, François Vaillant, Huei-Rong Chen, Caleb A. Dawson , et al. · 2019

Breast cancer is characterized by histological and functional heterogeneity, posing a clinical challenge for patient treatment. Emerging evidence suggests that the distinct subtypes reflect the repertoire of genetic alterations and the tar…

Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging Open

Anne C. Rios, Bianca D. Capaldo, François Vaillant, Bhupinder Pal, Ravian van Ineveld , et al. · 2019

Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging Open

Anne C. Rios, Bianca D. Capaldo, François Vaillant, Bhupinder Pal, Ravian van Ineveld , et al. · 2019

Canonical PRC2 function is essential for mammary gland development and affects chromatin compaction in mammary organoids Open

Ewa M. Michalak, Michael J. G. Milevskiy, Rachel Joyce, Johanna F. Dekkers, Paul R. Jamieson , et al. · 2018

Distinct transcriptional states are maintained through organization of chromatin, resulting from the sum of numerous repressive and active histone modifications, into tightly packaged heterochromatin versus more accessible euchromatin. Pol…

Mutant IDH1 and thrombosis in gliomas Open

Dusten Unruh, Steven R. Schwarze, Laith Khoury, Cheddhi Thomas, Meijing Wu , et al. · 2016

TMIC-13MUTANT<i>IDH1/2</i>SUPPRESSES LOCAL AND SYSTEMIC THROMBOSIS IN GLIOMA PATIENTS Open

Steven R. Schwarze, Laith Khoury, Cheddhi Thomas, Carolina Benjamin, Rui Chen , et al. · 2015

Mutations in isocitrate dehydrogenase 1 and 2 (mutIDH1/2) are common in gliomas, resulting in enzymes that produce D-2-hydroxyglutarate (D-2-HG). The effects of mutIDH1/2 on the microenvironment, including thrombosis, are not known. In dis…

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