Henry C. Powell
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View article: Developing a functional non-animal CNS stress model utilizing long-term potentiation with human iPSC-cortical neurons to evaluate therapeutics
Developing a functional non-animal CNS stress model utilizing long-term potentiation with human iPSC-cortical neurons to evaluate therapeutics Open
Cortisol, the main stress hormone of the hypothalamic-pituitary-adrenal (HPA) axis, has been hypothesized to cause considerable detriment to cognitive function in both a time and concentration-dependent manner. However, there is a current …
View article: Preclinical development of a continuous fetal lactate biosensor to detect acidosis
Preclinical development of a continuous fetal lactate biosensor to detect acidosis Open
Introduction Accurate detection of fetal acidosis in labor is an unmet clinical need. Objectives of this study are: To run a pilot validation of a subcutaneous biosensor for continuous lactate monitoring (CLM) to detect acidosis in a fetal…