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View article: MỨC ĐỘ ĐAU VÀ LO LẮNG CỦA TRẺ EM TRONG ĐIỀU TRỊ SÂU RĂNG: SO SÁNH GIỮA LASER ER:YAG VÀ KHOAN CƠ HỌC
MỨC ĐỘ ĐAU VÀ LO LẮNG CỦA TRẺ EM TRONG ĐIỀU TRỊ SÂU RĂNG: SO SÁNH GIỮA LASER ER:YAG VÀ KHOAN CƠ HỌC Open
Mở đầu: Trong điều trị sâu răng ở trẻ em, Laser Er:YAG là phương pháp xâm lấn tối thiểu, ít đau, ít rung và không gây tiếng ồn, từ đó cải thiện sự hợp tác của trẻ trong điều trị. Nghiên cứu nhằm so sánh mức độ đau, lo lắng giữa phương pháp…
View article: Sustainable recycling of polyamides via C–N bond cleavage facilitated by methyl tosylate under mild conditions
Sustainable recycling of polyamides via C–N bond cleavage facilitated by methyl tosylate under mild conditions Open
View article: Bio-inspired manganese-catalyzed deaminative hydroxylation of benzyl amines to corresponding alcohols
Bio-inspired manganese-catalyzed deaminative hydroxylation of benzyl amines to corresponding alcohols Open
Direct conversion of amines to corresponding alcohols is challenging even under harsh reaction conditions. Inspired by enzymatic transamination, we present a transamination borrowing-hydrogen strategy that enables the direct and selective …
View article: Đăc điêm lâm sang cua bênh nhân Rôi loan thai dương ham: Hồi cứu trên 522 bệnh án
Đăc điêm lâm sang cua bênh nhân Rôi loan thai dương ham: Hồi cứu trên 522 bệnh án Open
Đặt vấn đề: Rối loạn thái dương hàm (RLTDH) ảnh hưởng đến chức năng nhai và chất lượng cuộc sống, nhưng dữ liệu về đặc điểm tuổi, giới tính và yếu tố nguy cơ là nghiến răng và/hoặc cắn chặt răng trong mô hình bệnh sinh của RLTDH tại Việt N…
View article: So sánh quy trình thực hiện máng nhai ổn định bằng phương pháp kỹ thuật số và phương pháp thông thường
So sánh quy trình thực hiện máng nhai ổn định bằng phương pháp kỹ thuật số và phương pháp thông thường Open
Đặt vấn đề: Rối loạn thái dương hàm (RLTDH) là một tình trạng đau miệng mặt phổ biến trong nha khoa. Để kiểm soát RLTDH, máng nhai loại ổn định là một trong những chỉ định phổ biến nhất. Hiện nay, nhiều nghiên cứu cho thấy ứng dụng quy trì…
View article: Khảo sát mức độ đau, trầm trọng hóa đau, trầm cảm và lo âu trên bệnh nhân rối loạn thái dương hàm
Khảo sát mức độ đau, trầm trọng hóa đau, trầm cảm và lo âu trên bệnh nhân rối loạn thái dương hàm Open
Mục tiêu: Khảo sát mức độ đau, trầm trọng hóa đau, trầm cảm và lo âu trên bệnh nhân rối loạn thái dương hàm (RLTDH) đến khám tại Phòng khám chuyên khoa Răng Hàm Mặt - Đại học Y Dược Thành phố Hồ Chí Minh từ năm 2021 đến năm 2023. Đối tượng…
View article: Towards an AI co-scientist
Towards an AI co-scientist Open
Scientific discovery relies on scientists generating novel hypotheses that undergo rigorous experimental validation. To augment this process, we introduce an AI co-scientist, a multi-agent system built on Gemini 2.0. The AI co-scientist is…
View article: Theoretical Investigation of Competitive Adsorption of Light and Heavy Rare Earth Ions on the (001) Surface of Kaolinite
Theoretical Investigation of Competitive Adsorption of Light and Heavy Rare Earth Ions on the (001) Surface of Kaolinite Open
Kaolinite is the primary mineral in ion-adsorption rare earth ores, and improving our understanding of the adsorption state of REEs on kaolinite will benefit efforts to leach REEs from these ores. In order to explain why Eu3+ ions exhibit …
View article: Tx-LLM: A Large Language Model for Therapeutics
Tx-LLM: A Large Language Model for Therapeutics Open
Developing therapeutics is a lengthy and expensive process that requires the satisfaction of many different criteria, and AI models capable of expediting the process would be invaluable. However, the majority of current AI approaches addre…
View article: Advancing Multimodal Medical Capabilities of Gemini
Advancing Multimodal Medical Capabilities of Gemini Open
Many clinical tasks require an understanding of specialized data, such as medical images and genomics, which is not typically found in general-purpose large multimodal models. Building upon Gemini's multimodal models, we develop several mo…
View article: Consensus, dissensus and synergy between clinicians and specialist foundation models in radiology report generation
Consensus, dissensus and synergy between clinicians and specialist foundation models in radiology report generation Open
Radiology reports are an instrumental part of modern medicine, informing key clinical decisions such as diagnosis and treatment. The worldwide shortage of radiologists, however, restricts access to expert care and imposes heavy workloads, …
View article: Towards Conversational Diagnostic AI
Towards Conversational Diagnostic AI Open
At the heart of medicine lies the physician-patient dialogue, where skillful history-taking paves the way for accurate diagnosis, effective management, and enduring trust. Artificial Intelligence (AI) systems capable of diagnostic dialogue…
View article: Towards Accurate Differential Diagnosis with Large Language Models
Towards Accurate Differential Diagnosis with Large Language Models Open
An accurate differential diagnosis (DDx) is a cornerstone of medical care, often reached through an iterative process of interpretation that combines clinical history, physical examination, investigations and procedures. Interactive interf…
View article: Consensus, dissensus and synergy between clinicians and specialist foundation models in radiology report generation
Consensus, dissensus and synergy between clinicians and specialist foundation models in radiology report generation Open
Radiology reports are an instrumental part of modern medicine, informing key clinical decisions such as diagnosis and treatment. The worldwide shortage of radiologists, however, restricts access to expert care and imposes heavy workloads, …
View article: Genetic Discovery Enabled by A Large Language Model
Genetic Discovery Enabled by A Large Language Model Open
Artificial intelligence (AI) has been used in many areas of medicine, and recently large language models (LLMs) have shown potential utility for clinical applications. However, since we do not know if the use of LLMs can accelerate the pac…
View article: Efficient Synthesis of Ractopamine‐<i>D<sub>3</sub></i> via Epoxide‐Opening Strategy
Efficient Synthesis of Ractopamine‐<i>D<sub>3</sub></i> via Epoxide‐Opening Strategy Open
The incorporation of deuterium isotopes into illicit additives like ractopamine holds significant promise for enabling swift and accurate detection. However, current synthetic methodologies for deuterium labeling often involve intricate an…
View article: Publisher Correction: Large language models encode clinical knowledge
Publisher Correction: Large language models encode clinical knowledge Open
View article: Towards Generalist Biomedical AI
Towards Generalist Biomedical AI Open
Medicine is inherently multimodal, with rich data modalities spanning text, imaging, genomics, and more. Generalist biomedical artificial intelligence (AI) systems that flexibly encode, integrate, and interpret this data at scale can poten…
View article: Large language models encode clinical knowledge
Large language models encode clinical knowledge Open
Large language models (LLMs) have demonstrated impressive capabilities, but the bar for clinical applications is high. Attempts to assess the clinical knowledge of models typically rely on automated evaluations based on limited benchmarks.…
View article: Towards Expert-Level Medical Question Answering with Large Language Models
Towards Expert-Level Medical Question Answering with Large Language Models Open
Recent artificial intelligence (AI) systems have reached milestones in "grand challenges" ranging from Go to protein-folding. The capability to retrieve medical knowledge, reason over it, and answer medical questions comparably to physicia…
View article: Large Language Models Encode Clinical Knowledge
Large Language Models Encode Clinical Knowledge Open
Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledg…
View article: CCDC 2170512: Experimental Crystal Structure Determination
CCDC 2170512: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Inferring latent neural sources via deep transcoding of simultaneously acquired EEG and fMRI
Inferring latent neural sources via deep transcoding of simultaneously acquired EEG and fMRI Open
Simultaneous EEG-fMRI is a multi-modal neuroimaging technique that provides complementary spatial and temporal resolution. Challenging has been developing principled and interpretable approaches for fusing the modalities, specifically appr…
View article: Directly Knitted Ruthenium Pincer Complexes with Enhanced Activity as Recyclable Single-Site Catalysts for Hydrogenation of CO <sub>2</sub> to Methanol
Directly Knitted Ruthenium Pincer Complexes with Enhanced Activity as Recyclable Single-Site Catalysts for Hydrogenation of CO <sub>2</sub> to Methanol Open
Open AccessCCS ChemistryRESEARCH ARTICLES16 Aug 2022Directly Knitted Ruthenium Pincer Complexes with Enhanced Activity as Recyclable Single-Site Catalysts for Hydrogenation of CO2 to Methanol Daheng Wen, Jiangbo Chen, Qingshu Zheng, Siqi Y…
View article: Engineering Cupriavidus Necator H16 for Heterotrophic and Autotrophic Production of Myo-Inositol
Engineering Cupriavidus Necator H16 for Heterotrophic and Autotrophic Production of Myo-Inositol Open
View article: Lamellar Enzyme-Metal–Organic Framework Composites Enable Catalysis on Large Substrates
Lamellar Enzyme-Metal–Organic Framework Composites Enable Catalysis on Large Substrates Open
Open AccessCCS ChemistryCOMMUNICATION1 Mar 2022Lamellar Enzyme-Metal–Organic Framework Composites Enable Catalysis on Large Substrates Yunjie Tu, He Li, Tao Tu and Qi Zhang Yunjie Tu Department of Chemistry, Fudan University, Shanghai 2004…
View article: Robust NHC-palladacycles-catalyzed Suzuki−Miyaura cross-coupling of amides via C-N activation
Robust NHC-palladacycles-catalyzed Suzuki−Miyaura cross-coupling of amides via C-N activation Open
View article: Reversible stimuli-responsive chromism of a cyclometallated platinum(<scp>ii</scp>) complex
Reversible stimuli-responsive chromism of a cyclometallated platinum(<span>ii</span>) complex Open
We report the reversible chromism and luminescence of a cyclometalated platinum(ii) complex that forms dimers, with close Pt⋯Pt interactions that can be modulated by solvent and temperature.
View article: Towards Unsupervised Speech Recognition and Synthesis with Quantized\n Speech Representation Learning
Towards Unsupervised Speech Recognition and Synthesis with Quantized\n Speech Representation Learning Open
In this paper we propose a Sequential Representation Quantization AutoEncoder\n(SeqRQ-AE) to learn from primarily unpaired audio data and produce sequences of\nrepresentations very close to phoneme sequences of speech utterances. This is\n…
View article: CCDC 1947510: Experimental Crystal Structure Determination
CCDC 1947510: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …