Shannon Brown
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View article: Incarcerated Ink: A Case of Mycobacterium chelonae
Incarcerated Ink: A Case of Mycobacterium chelonae Open
A 30-year-old African American male presented with pain and swelling of the right foot one month after receiving a tattoo on this foot in prison. During his admission for presumed cellulitis, he developed a rash on his contralateral (left)…
View article: Pancreatic Cancer Presenting to the Dermatology Clinic
Pancreatic Cancer Presenting to the Dermatology Clinic Open
In patients with skin of color, jaundice may present more discretely, which can lead to a delay in diagnosing underlying disease and widening racial disparity gaps. It is important for clinicians to recognize the subtleties of jaundice to …
View article: Azithromycin as a Possible Cause of Linear IgA Bullous Dermatosis
Azithromycin as a Possible Cause of Linear IgA Bullous Dermatosis Open
We present a rare case of linear IgA bullous dermatosis (LABD) in a 72-year-old male associated with the use of azithromycin. LABD presents as subepidermal blisters due to IgA antibodies targeting BPAG2, a component of hemidesmosomes. LABD…
View article: Genetics of <scp>non‐isolated</scp> hemivertebra: A systematic review of fetal, neonatal, and infant cases
Genetics of <span>non‐isolated</span> hemivertebra: A systematic review of fetal, neonatal, and infant cases Open
Hemivertebra is a congenital vertebral malformation caused by unilateral failure of formation during embryogenesis that may be associated with additional abnormalities. A systematic review was conducted to investigate genetic etiologies of…
View article: Single-View Echocardiography by Nonexpert Practitioners to Detect Rheumatic Heart Disease: A Prospective Study of Diagnostic Accuracy
Single-View Echocardiography by Nonexpert Practitioners to Detect Rheumatic Heart Disease: A Prospective Study of Diagnostic Accuracy Open
Background: Echocardiographic screening can detect asymptomatic cases of rheumatic heart disease (RHD), facilitating access to treatment. Barriers to implementation of echocardiographic screening include the requirement for expensive equip…
View article: Standardisation of allergen products: 4. Validation of a candidate European Pharmacopoeia standard method for quantification of major grass pollen allergen Phl p 5
Standardisation of allergen products: 4. Validation of a candidate European Pharmacopoeia standard method for quantification of major grass pollen allergen Phl p 5 Open
Background The aim of the BSP090 project is the establishment of European Pharmacopoeia Chemical Reference Substances (CRSs) in combination with corresponding standard ELISA methods for quantification of major allergens in allergen product…
View article: Epigenetic marks of prenatal air pollution exposure found in multiple tissues relevant for child health
Epigenetic marks of prenatal air pollution exposure found in multiple tissues relevant for child health Open
We observed global, locus, and sex-specific methylation changes associated with prenatal NO2 and O3 exposures. Our findings support DNAm is a biologic target of prenatal air pollutant exposures and highlight epigenetic involvement in sex-s…
View article: Focal Cutaneous Squamous Cell Carcinoma Following Radium-223 Extravasation
Focal Cutaneous Squamous Cell Carcinoma Following Radium-223 Extravasation Open
Long-term sequelae due to extravasation of intravenous radioisotopes resulting in radiation injuries are rarely reported. As the use of radioactive isotopes for the treatment of osteoblastic metastases increases, information regarding the …
View article: Anticonvulsant Hypersensitivity Syndrome Secondary to Carbamazepine
Anticonvulsant Hypersensitivity Syndrome Secondary to Carbamazepine Open
Anticonvulsant hypersensitivity syndrome (AHS) is a potentially fatal multiorgan drug reaction that presents with various cutaneous eruptions. There is a genetic predisposition to such reactions. We present a young woman with AHS due to ca…
View article: Bevacizumab-Induced Pityriasis Rubra Pilaris-Like Eruption
Bevacizumab-Induced Pityriasis Rubra Pilaris-Like Eruption Open
Pityriasis rubra pilaris is a rare inflammatory disorder characterized by follicular papules on an erythematous base often exhibiting islands of unaffected skin, follicular plugging, and palmoplantar hyperkeratosis. While vitamin A deficie…
View article: DNA methylation of cord blood cell types: Applications for mixed cell birth studies
DNA methylation of cord blood cell types: Applications for mixed cell birth studies Open
Epigenome-wide association studies of disease widely use DNA methylation measured in blood as a surrogate tissue. Cell proportions can vary between people and confound associations of exposure or outcome. An adequate reference panel for es…
View article: New Mission, New Orbit, No Problem - Applying the Responsive Space Capability to Meet the ORS-6 Mission
New Mission, New Orbit, No Problem - Applying the Responsive Space Capability to Meet the ORS-6 Mission Open
From a re-purposed Air Force bus, to a new reconfigurable NASA sensor, to the commercial ride-share launch service, the ORS-6 mission is a model of how flexible architecture, agile management, and creative engineering adjustments to herita…