Cameron P. Simmons
YOU?
Author Swipe
View article: Long-Term Durability and Public Health Impact of City-Wide wMel Wolbachia Mosquito Releases in Niterói, Brazil, During a Dengue Epidemic Surge
Long-Term Durability and Public Health Impact of City-Wide wMel Wolbachia Mosquito Releases in Niterói, Brazil, During a Dengue Epidemic Surge Open
In 2024, the Americas experienced the largest dengue outbreak on record and Brazil was among the worst affected countries, reporting 6.6 million cases and 6200 deaths. We report the long-term entomological and epidemiological effectiveness…
View article: Long-term durability and public health impact of city-wide<i>w</i>Mel<i>Wolbachia</i>mosquito releases in Niterói, Brazil during a dengue epidemic surge
Long-term durability and public health impact of city-wide<i>w</i>Mel<i>Wolbachia</i>mosquito releases in Niterói, Brazil during a dengue epidemic surge Open
In 2024, the Americas region experienced the largest dengue outbreak on record and Brazil was among the worst affected countries, reporting 6.6 million cases and 6,200 deaths. We report the long-term entomological and epidemiological effec…
View article: High genomic stability of <i>w</i>Mel <i>Wolbachia</i> after introgression in three geographically distinct <i>Aedes aegypti</i> populations
High genomic stability of <i>w</i>Mel <i>Wolbachia</i> after introgression in three geographically distinct <i>Aedes aegypti</i> populations Open
The introgression of w Mel Wolbachia into Aedes aegypti populations is being used for the biocontrol of arboviruses such as dengue and chikungunya in 15 countries to date. A w Mel infection in Ae. aegypti both reduces the transmission of v…
View article: Performance evaluation of the Qiagen BK virus ASR on the NeuMoDx system
Performance evaluation of the Qiagen BK virus ASR on the NeuMoDx system Open
Background: BK virus (BKV) is the main cause of polyomavirus‐associated nephropathy in kidney transplant patients and hemorrhagic cystitis in bone marrow recipients. BKV quantitation by PCR is crucial in diagnostic and therapeutic manageme…
View article: Dengue virus genomic surveillance in the applying Wolbachia to eliminate dengue trial reveals genotypic efficacy and disruption of focal transmission
Dengue virus genomic surveillance in the applying Wolbachia to eliminate dengue trial reveals genotypic efficacy and disruption of focal transmission Open
View article: <i>Wolbachia</i>introgression in<i>Ae. aegypti</i>is accompanied by variable loss – a multi-country assessment
<i>Wolbachia</i>introgression in<i>Ae. aegypti</i>is accompanied by variable loss – a multi-country assessment Open
The w Mel and w AlbB strains of the bacterial endosymbiont Wolbachia are being introgressed into Aedes aegypti populations as a biocontrol method to reduce the transmission of medically important arboviruses. Successful introgression of Wo…
View article: Dengue viremia kinetics and effects on platelet count and clinical outcomes: An analysis of 2340 patients from Vietnam
Dengue viremia kinetics and effects on platelet count and clinical outcomes: An analysis of 2340 patients from Vietnam Open
Background: Viremia is a critical factor in understanding the pathogenesis of dengue infection, but limited data exist on viremia kinetics. This study aimed to investigate the kinetics of viremia and its effects on subsequent platelet coun…
View article: Author response: Dengue viremia kinetics and effects on platelet count and clinical outcomes: An analysis of 2340 patients from Vietnam
Author response: Dengue viremia kinetics and effects on platelet count and clinical outcomes: An analysis of 2340 patients from Vietnam Open
View article: Dengue Viremia Kinetics and Effects on Platelet Count and Clinical Outcomes: An Analysis of 2340 Patients from Vietnam
Dengue Viremia Kinetics and Effects on Platelet Count and Clinical Outcomes: An Analysis of 2340 Patients from Vietnam Open
Background Viremia is a critical factor in understanding the pathogenesis of dengue infection, but limited data exist on viremia kinetics. This study aimed to investigate the kinetics of viremia and its effects on subsequent platelet count…
View article: Reviewer #1 (Public Review): Dengue Viremia Kinetics and Effects on Platelet Count and Clinical Outcomes: An Analysis of 2340 Patients from Vietnam
Reviewer #1 (Public Review): Dengue Viremia Kinetics and Effects on Platelet Count and Clinical Outcomes: An Analysis of 2340 Patients from Vietnam Open
Viremia is a critical factor in understanding the pathogenesis of dengue infection, but limited data exist on viremia kinetics. This study aimed to investigate the kinetics of viremia and its effects on subsequent platelet count, severe de…
View article: Author response: Dengue Viremia Kinetics and Effects on Platelet Count and Clinical Outcomes: An Analysis of 2340 Patients from Vietnam
Author response: Dengue Viremia Kinetics and Effects on Platelet Count and Clinical Outcomes: An Analysis of 2340 Patients from Vietnam Open
Viremia is a critical factor in understanding the pathogenesis of dengue infection, but limited data exist on viremia kinetics. This study aimed to investigate the kinetics of viremia and its effects on subsequent platelet count, severe de…
View article: Reviewer #2 (Public Review): Dengue Viremia Kinetics and Effects on Platelet Count and Clinical Outcomes: An Analysis of 2340 Patients from Vietnam
Reviewer #2 (Public Review): Dengue Viremia Kinetics and Effects on Platelet Count and Clinical Outcomes: An Analysis of 2340 Patients from Vietnam Open
Viremia is a critical factor in understanding the pathogenesis of dengue infection, but limited data exist on viremia kinetics. This study aimed to investigate the kinetics of viremia and its effects on subsequent platelet count, severe de…
View article: Reanalysis of cluster randomised trial data to account for exposure misclassification using a per-protocol and complier-restricted approach
Reanalysis of cluster randomised trial data to account for exposure misclassification using a per-protocol and complier-restricted approach Open
View article: Successful introgression of wMel Wolbachia into Aedes aegypti populations in Fiji, Vanuatu and Kiribati
Successful introgression of wMel Wolbachia into Aedes aegypti populations in Fiji, Vanuatu and Kiribati Open
Pacific Island countries have experienced periodic dengue, chikungunya and Zika outbreaks for decades. The prevention and control of these mosquito-borne diseases rely heavily on control of Aedes aegypti mosquitoes, which in most settings …
View article: Dengue Viremia Kinetics and Effects on Platelet Count and Clinical Outcomes: An Analysis of 2340 Patients from Vietnam
Dengue Viremia Kinetics and Effects on Platelet Count and Clinical Outcomes: An Analysis of 2340 Patients from Vietnam Open
Background Viremia is a critical factor in understanding the pathogenesis of dengue infection, but limited data exist on viremia kinetics. This study aimed to investigate the kinetics of viremia and its effects on subsequent platelet count…
View article: Dengue viremia kinetics and effects on platelet count and clinical outcomes: An analysis of 2340 patients from Vietnam
Dengue viremia kinetics and effects on platelet count and clinical outcomes: An analysis of 2340 patients from Vietnam Open
Background: Viremia is a critical factor in understanding the pathogenesis of dengue infection, but limited data exist on viremia kinetics. This study aimed to investigate the kinetics of viremia and its effects on subsequent platelet coun…
View article: A Serotype-Specific and Tiled Amplicon Multiplex Pcr Method for Whole Genome Sequencing of Dengue Virus
A Serotype-Specific and Tiled Amplicon Multiplex Pcr Method for Whole Genome Sequencing of Dengue Virus Open
View article: Antiviral <i>Wolbachia</i> strains associate with <i>Aedes aegypti</i> endoplasmic reticulum membranes and induce lipid droplet formation to restrict dengue virus replication
Antiviral <i>Wolbachia</i> strains associate with <i>Aedes aegypti</i> endoplasmic reticulum membranes and induce lipid droplet formation to restrict dengue virus replication Open
Aedes aegypti transmits a range of important human pathogenic viruses like dengue. However, infection of Ae. aegypti with the insect endosymbiotic bacterium, Wolbachia , reduces the risk of mosquito to human viral transmission. Wolbachia i…
View article: Reduced dengue incidence following city-wide wMel Wolbachia mosquito releases throughout three Colombian cities: Interrupted time series analysis and a prospective case-control study
Reduced dengue incidence following city-wide wMel Wolbachia mosquito releases throughout three Colombian cities: Interrupted time series analysis and a prospective case-control study Open
Background The introduction of Wolbachia ( w Mel strain) into Aedes aegypti mosquitoes reduces their capacity to transmit dengue and other arboviruses. Randomised and non-randomised studies in multiple countries have shown significant redu…
View article: Utility of surveillance data for planning for dengue elimination in Yogyakarta, Indonesia: a scenario-tree modelling approach
Utility of surveillance data for planning for dengue elimination in Yogyakarta, Indonesia: a scenario-tree modelling approach Open
Introduction Field trials and modelling studies suggest that elimination of dengue transmission may be possible through widespread release of Aedes aegypti mosquitoes infected with the insect bacterium Wolbachia pipientis ( w Mel strain), …
View article: Dengue Viremia Kinetics and Effects on Platelet Count and Clinical Outcomes: An Analysis of 2340 Patients from Vietnam
Dengue Viremia Kinetics and Effects on Platelet Count and Clinical Outcomes: An Analysis of 2340 Patients from Vietnam Open
Background Viremia is a critical factor in understanding the pathogenesis of dengue infection, but limited data exist on viremia kinetics. This study aimed to investigate the kinetics of viremia and its effects on subsequent platelet count…
View article: Adverse childhood experiences, social participation and multimorbidity risk in Europe
Adverse childhood experiences, social participation and multimorbidity risk in Europe Open
Background Adverse childhood experiences (ACEs) are linked to multimorbidity, but evidence from longitudinal research on potential macro and micro-level protective factors is lacking. We investigated the associations between ACEs, social p…
View article: Antiviral<i>Wolbachia</i>strains associate with<i>Aedes aegypti</i>endoplasmic reticulum membranes and disturb host cell lipid distribution to restrict dengue virus replication
Antiviral<i>Wolbachia</i>strains associate with<i>Aedes aegypti</i>endoplasmic reticulum membranes and disturb host cell lipid distribution to restrict dengue virus replication Open
The insect endosymbiotic bacterium Wolbachia pipientis is being utilised as a biocontrol tool to reduce the incidence of Aedes aegypti -transmitted viral diseases like dengue. However, the precise mechanisms underpinning Wolbachia ’s antiv…
View article: Direct mosquito feedings on dengue-2 virus-infected people reveal dynamics of human infectiousness
Direct mosquito feedings on dengue-2 virus-infected people reveal dynamics of human infectiousness Open
Dengue virus (DENV) transmission from humans to mosquitoes is a poorly documented, but critical component of DENV epidemiology. Magnitude of viremia is the primary determinant of successful human-to-mosquito DENV transmission. People with …
View article: Wolbachia wMel strain-mediated effects on dengue virus vertical transmission from Aedes aegypti to their offspring
Wolbachia wMel strain-mediated effects on dengue virus vertical transmission from Aedes aegypti to their offspring Open
View article: Adenovirus vector produced Zika virus-like particles induce a long-lived neutralising antibody response in mice
Adenovirus vector produced Zika virus-like particles induce a long-lived neutralising antibody response in mice Open
Countermeasures against Zika virus (ZIKV) epidemics are urgently needed. In this study we generated a ZIKV virus-like particle (VLP) based vaccine candidate and assessed the immunogenicity of these particles in mice. The ZIKV-VLPs were mor…
View article: Development of virus-like particles with inbuilt immunostimulatory properties as vaccine candidates
Development of virus-like particles with inbuilt immunostimulatory properties as vaccine candidates Open
The development of virus-like particle (VLP) based vaccines for human papillomavirus, hepatitis B and hepatitis E viruses represented a breakthrough in vaccine development. However, for dengue and COVID-19, technical complications, such as…
View article: An economic evaluation of Wolbachia deployments for dengue control in Vietnam
An economic evaluation of Wolbachia deployments for dengue control in Vietnam Open
Introduction Dengue is a major public health challenge and a growing problem due to climate change. The release of Aedes aegypti mosquitoes infected with the intracellular bacterium Wolbachia is a novel form of vector control against dengu…
View article: Wolbachia wMel-mediated effects on dengue virus vertical transmission from Aedes aegypti to their offspring
Wolbachia wMel-mediated effects on dengue virus vertical transmission from Aedes aegypti to their offspring Open
Background: Dengue viruses (DENV) can be transmitted vertically in Aedes aegpti (Ae. aegypti) mosquitoes. Whether the endosymbiont Wolbachia ( w Mel strain) can reduce the incidence of vertical transmission of DENV from infected females to…
View article: Reanalysis of cluster randomised trial data to account for exposure misclassification using a per-protocol and complier-restricted approach
Reanalysis of cluster randomised trial data to account for exposure misclassification using a per-protocol and complier-restricted approach Open
The intention-to-treat (ITT) analysis of the Applying Wolbachia to Eliminate Dengue (AWED) trial estimated a protective efficacy of 77.1% for participants resident in areas randomised to receive releases of w Mel-infected Aedes aegypti mos…