Cameron Postnikoff
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View article: Tear Film miRNAs and Their Association With Human Dry Eye Disease
Tear Film miRNAs and Their Association With Human Dry Eye Disease Open
This study determined that EVs are present in the tear film and that tear EVs contain miRNAs that may be associated with DED inflammatory pathways.
View article: Tear Film miRNAs and Their Association With Human Dry Eye Disease
Tear Film miRNAs and Their Association With Human Dry Eye Disease Open
miRNAs can regulate inflammatory pathways. The purpose of this work was to determine if inflammatory-related tear film miRNAs are associated with extracellular vesicles (EVs) in human non-Sjögren’s Syndrome dry eye disease (DED) participan…
View article: The closed eye harbors a unique microbiome in dry eye disease
The closed eye harbors a unique microbiome in dry eye disease Open
Dry eye affects millions of individuals. In experimental models, dry eye disease is associated with T helper cell 17-mediated inflammation of the ocular surface that may cause persistent damage to the corneal epithelium. However, the initi…
View article: Identification of Leukocytes Associated With Midday Fogging in the Post-Lens Tear Film of Scleral Contact Lens Wearers
Identification of Leukocytes Associated With Midday Fogging in the Post-Lens Tear Film of Scleral Contact Lens Wearers Open
Leukocytes, predominated by neutrophils, are present in the post-lens tear film of ScCL wearers, and in particular wearers with greater ScCL corneal clearance have greater odds of having midday fogging.
View article: Neutrophil and T-Cell Homeostasis in the Closed Eye
Neutrophil and T-Cell Homeostasis in the Closed Eye Open
Neutrophils begin accumulating in the closed eye conjunctival sac much earlier than previously demonstrated. The closed eye tears are also populated with T cells, including a subset of Th17 cells. The closed eye environment is more inflamm…