Camille Taillé
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View article: Impact of Fungal Sensitization on Long-Term Outcomes in Severe Asthma
Impact of Fungal Sensitization on Long-Term Outcomes in Severe Asthma Open
Patients with SAFS represent a particularly severe asthma phenotype, even after treatment with biologics. Nonetheless, they show a significant response to standardized care for severe asthma.
View article: Clinical Characteristics of Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia (DIPNECH)
Clinical Characteristics of Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia (DIPNECH) Open
RATIONALE DIPNECH is characterized by diffuse bronchial hyperplasia of pulmonary neuroendocrine cells which are situated within the walls of bronchi and bronchioles. Presenting symptoms are non-specific and the clinical course varies, maki…
View article: Response to Biologics Along a Gradient of T2 Involvement in Patients With Severe Asthma: A Data-Driven Biomarker Clustering Approach
Response to Biologics Along a Gradient of T2 Involvement in Patients With Severe Asthma: A Data-Driven Biomarker Clustering Approach Open
T2-targeting biologics have utility in the management of asthma with low T2 involvement, but more effective therapies are needed. Further research is warranted to identify specific pathogenic pathways at the lower end of the T2 spectrum th…
View article: Decrease in Eosinophil‐Derived‐Neurotoxin With Mepolizumab Is Associated With Asthma Improvement
Decrease in Eosinophil‐Derived‐Neurotoxin With Mepolizumab Is Associated With Asthma Improvement Open
International audience
View article: Monosensitization vs Polysensitization in Severe Asthma: Implications for Disease Severity
Monosensitization vs Polysensitization in Severe Asthma: Implications for Disease Severity Open
Monosensitized patients exhibited more severe disease and greater airway obstruction compared to polysensitized individuals. These findings suggest that allergies, especially in cases of late-onset asthma, may not be a significant determin…
View article: Validation and cross-cultural insights of the French translation of the Severe Asthma Questionnaire
Validation and cross-cultural insights of the French translation of the Severe Asthma Questionnaire Open
Demonstrating consistent psychometric properties with the English version, the French translation of the SAQ can be used by clinicians to assess French-speaking patients with severe asthma and understand the disease's impact on quality …
View article: Factitious severe asthma: A diagnostic challenge in the era of biologics
Factitious severe asthma: A diagnostic challenge in the era of biologics Open
View article: International Severe Asthma Registry (ISAR): 2017–2024 Status and Progress Update
International Severe Asthma Registry (ISAR): 2017–2024 Status and Progress Update Open
The International Severe Asthma Registry (ISAR) was established in 2017 to advance the understanding of severe asthma and its management, thereby improving patient care worldwide. As the first global registry for adults with severe asthma,…
View article: Chronic rhinosinusitis with nasal polyps: Key considerations in the multidisciplinary team approach
Chronic rhinosinusitis with nasal polyps: Key considerations in the multidisciplinary team approach Open
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a recurrent inflammatory disease associated with several comorbidities and a significant disease burden for patients. Treatments include corticosteroids and sinonasal surgery,…
View article: What is the true target population for biologics in real-life COPD or asthma-COPD overlap patients?
What is the true target population for biologics in real-life COPD or asthma-COPD overlap patients? Open
Introduction Biologics provide significant benefits in asthma, reducing exacerbations and symptoms. Some biologics have shown promising results in small subgroups of patients with chronic obstructive pulmonary disease (COPD) and frequent e…
View article: Lack of efficacy of tocilizumab in acute exacerbation of pulmonary fibrosis
Lack of efficacy of tocilizumab in acute exacerbation of pulmonary fibrosis Open
Given the high mortality rate observed in our data, tocilizumab is not recommended as a salvage therapy for patients affected by acute exacerbation of pulmonary fibrosis who did not show clinical improvement after three steroids bolus
View article: Allergen Immunotherapy for the Prevention and Treatment of Asthma
Allergen Immunotherapy for the Prevention and Treatment of Asthma Open
Allergic asthma is the predominant phenotype among asthmatics. Although conventional pharmacotherapy is a central component in the management of asthma, it does not enable control of asthma symptoms in all patients. In recent decades, some…
View article: A RESPONSE to anti–IL-5 therapy in comorbid patients with chronic rhinosinusitis with nasal polyps and severe asthma: Study protocol
A RESPONSE to anti–IL-5 therapy in comorbid patients with chronic rhinosinusitis with nasal polyps and severe asthma: Study protocol Open
View article: Cystic lung in sarcoidosis: Clinico‐radiologic characteristic and evolution
Cystic lung in sarcoidosis: Clinico‐radiologic characteristic and evolution Open
Background and Objective Sarcoidosis can manifest with atypical findings on chest computed tomography (CT). Cysts are a rare manifestation of lung sarcoidosis. The aim of the study was to describe a series of patients with cystic sarcoidos…
View article: Intégration des méthodes géophysiques et géotechniques marines pour la définition du modèle géologique d'un site complexe – projet Haliotis II, Nice
Intégration des méthodes géophysiques et géotechniques marines pour la définition du modèle géologique d'un site complexe – projet Haliotis II, Nice Open
Bonjour, Ce projet touche un site à les reconnaissances géophysiques et géotechniques sont primordiales sur un talus connu pour avoir eu des glissements mais avec des problématiques également d'accès au site entre l'aéroport, les zones de …
View article: Long-term functional course of Sjögren's disease-associated interstitial lung disease
Long-term functional course of Sjögren's disease-associated interstitial lung disease Open
Background Interstitial lung disease (ILD) is common in primary Sjögren's disease (pSD); its functional course is poorly known. Our aim was to characterise the long-term functional course and prognosis in patients with pSD-ILD. We determin…
View article: Exploring Definitions and Predictors of Response to Biologics for Severe Asthma
Exploring Definitions and Predictors of Response to Biologics for Severe Asthma Open
View article: Exploring Definitions and Predictors of Severe Asthma Clinical Remission after Biologic Treatment in Adults
Exploring Definitions and Predictors of Severe Asthma Clinical Remission after Biologic Treatment in Adults Open
Rationale: There is no consensus on criteria to include in an asthma remission definition in real life. Factors associated with achieving remission after biologic initiation remain poorly understood. Objectives: To quantify t…
View article: Association between pre-biologic T2-biomarker combinations and response to biologics in patients with severe asthma
Association between pre-biologic T2-biomarker combinations and response to biologics in patients with severe asthma Open
Background To date, studies investigating the association between pre-biologic biomarker levels and post-biologic outcomes have been limited to single biomarkers and assessment of biologic efficacy from structured clinical trials. Aim To e…
View article: Transition of care from adolescence to early adulthood in severe asthmatic patients treated with omalizumab in real life
Transition of care from adolescence to early adulthood in severe asthmatic patients treated with omalizumab in real life Open
Half of severely asthmatic adolescents treated with omalizumab transitioning to adulthood discontinue the treatment, suggesting insufficient asthma control. However, most of the other half have low rates of HCRU markers, their asthma be…
View article: Severe asthma care trajectories: the French RAMSES cohort
Severe asthma care trajectories: the French RAMSES cohort Open
Background The French RAMSES study is an observational prospective multicentre real-life cohort including severe asthmatic subjects. The objective of the study was to compare the characteristics of patients, in terms of phenotype and asthm…
View article: CT Imaging Assessment of Response to Treatment in Allergic Bronchopulmonary Aspergillosis in Adults With Bronchial Asthma
CT Imaging Assessment of Response to Treatment in Allergic Bronchopulmonary Aspergillosis in Adults With Bronchial Asthma Open
View article: Reply to “Exploring the long-term effects of biologic initiation in severe asthma: Insights from the International Severe Asthma Registry”
Reply to “Exploring the long-term effects of biologic initiation in severe asthma: Insights from the International Severe Asthma Registry” Open
View article: Smoking, Urban Housing and Work-Aggravated Asthma are Associated with Asthma Severity in a Cross-Sectional Observational Study
Smoking, Urban Housing and Work-Aggravated Asthma are Associated with Asthma Severity in a Cross-Sectional Observational Study Open
While atopy and allergy were frequent among asthmatics, neither was associated with asthma severity. Modifiable environmental factors such as smoking, urban housing and work-aggravated asthma were independently associated with asthma sever…
View article: Articular manifestations related to anti-interleukin-5 therapies in severe asthma: a case series
Articular manifestations related to anti-interleukin-5 therapies in severe asthma: a case series Open
Articular manifestations should be screened before and during anti-IL-5/5R biologic treatment in severe asthma. Rigorous multidisciplinary team discussion should be carried out to assess the risk-benefit balance of withholding effective…
View article: Chest computed tomography and lung function one year following COVID-19 pneumonia
Chest computed tomography and lung function one year following COVID-19 pneumonia Open
Objectives: To characterise chest CT abnormalities one year following severe-to-critical COVID-19 pneumonia, assess their functional significance and analyse the time-course of CT signs. Methods: Retrospective observational monocentric stu…
View article: Association Between T2-related Comorbidities and Effectiveness of Biologics in Severe Asthma
Association Between T2-related Comorbidities and Effectiveness of Biologics in Severe Asthma Open
Rationale: Previous studies investigating the impact of comorbidities on the effectiveness of biologic agents have been relatively small and of short duration and have not compared classes of biologic agents. Objectives: To d…
View article: Eosinophilic granulomatosis with polyangiitis onset in severe asthma patients on monoclonal antibodies targeting type 2 inflammation: Report from the European <scp>EGPA</scp> study group
Eosinophilic granulomatosis with polyangiitis onset in severe asthma patients on monoclonal antibodies targeting type 2 inflammation: Report from the European <span>EGPA</span> study group Open
Anti-T2 monoclonal antibodies (mAbs) for severe-eosinophilc asthma have been recently investigated for EGPA.1 Few cases of severe asthma patients developing EGPA while on omalizumab,2 benralizumab3 or dupilumab4 have been published. We aim…
View article: Dupilumab for relapsing or refractory sinonasal and/or asthma manifestations in eosinophilic granulomatosis with polyangiitis: a European retrospective study
Dupilumab for relapsing or refractory sinonasal and/or asthma manifestations in eosinophilic granulomatosis with polyangiitis: a European retrospective study Open
View article: Analysis of comorbidities and multimorbidity in adult patients in the International Severe Asthma Registry
Analysis of comorbidities and multimorbidity in adult patients in the International Severe Asthma Registry Open