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View article: Erratum - Effect of Danggui Buxue decoction on hypoxia-induced injury of retinal Müller cells <i>in vitro</i>
Erratum - Effect of Danggui Buxue decoction on hypoxia-induced injury of retinal Müller cells <i>in vitro</i> Open
This corrects the article published in European Journal of Histochemistry 2024;68:4140 doi: 10.4081/ejh.2024.4140 IF: 2.1 Q4 B4 IF: 2.1 Q4 B4
View article: IL-1β-induced pericyte dysfunction with a secretory phenotype exacerbates retinal microenvironment inflammation via Hes1/STAT3 signaling pathway
IL-1β-induced pericyte dysfunction with a secretory phenotype exacerbates retinal microenvironment inflammation via Hes1/STAT3 signaling pathway Open
Retinal pericytes are mural cells surrounding capillaries to maintain the integrity of blood-retina barrier and regulate vascular behaviors. Pericyte loss has been considered as the hallmark of diabetic retinopathy (DR), which is a major c…
View article: Effect of Danggui Buxue decoction on hypoxia-induced injury of retinal Müller cells <i>in vitro</i>
Effect of Danggui Buxue decoction on hypoxia-induced injury of retinal Müller cells <i>in vitro</i> Open
Retinopathy is a common complication of diabetes mellitus and the leading cause of visual impairment. Danggui Buxue decoction (RRP) has been used as a traditional drug for the treatment of diabetic nephropathy for many years. The aim of th…
View article: The coexistence of low muscle mass and obesity evaluated by dual energy X‐ray absorptiometry, rather than low muscle mass or obesity alone, is associated with macrovascular but not microvascular complications in patients with type 2 diabetes mellitus
The coexistence of low muscle mass and obesity evaluated by dual energy X‐ray absorptiometry, rather than low muscle mass or obesity alone, is associated with macrovascular but not microvascular complications in patients with type 2 diabetes mellitus Open
Aim The prevalence of the coexistence of low muscle mass and obesity is increasing, particularly with a rising trend observed in patients diagnosed with type 2 diabetes mellitus (T2DM). However, the association between the coexistence of l…
View article: Dietary Intakes of Women with Gestational Diabetes Mellitus and Pregnancy Outcomes: A Prospective Observational Study
Dietary Intakes of Women with Gestational Diabetes Mellitus and Pregnancy Outcomes: A Prospective Observational Study Open
The daily diet of pregnant women with GDM in China did not meet the dietary guidelines or DRIs. The low intake of Vitamin D and iodine, the low dietary carbohydrate ratio, family history of diabetes, lack of exercise, and high gestational …
View article: Interleukin-6 promotes visceral adipose tissue accumulation during aging via inhibiting fat lipolysis
Interleukin-6 promotes visceral adipose tissue accumulation during aging via inhibiting fat lipolysis Open
Our findings identify a detrimental role of IL-6 during the aging process by promoting visceral adipose tissue accumulation through inhibition of lipolysis. Therefore, strategies aimed at preventing or reducing IL-6 levels may potentially …
View article: Traditional Chinese medicine could play an important role in diabetes management: Commentary on “National Chinese medicine guideline for the prevention and treatment of diabetes in primary care (2022)”
Traditional Chinese medicine could play an important role in diabetes management: Commentary on “National Chinese medicine guideline for the prevention and treatment of diabetes in primary care (2022)” Open
According to the latest data from International Diabetes Federation, China has the largest number of adults with diabetes, with ~140.9 million people having the disease.1 Traditional Chinese medicine (TCM) is one of the earliest complement…
View article: Sarcopenic obesity evaluated by dual energy X-ray absorptiometry, rather than sarcopenia or obesity alone, is associated with the macrovascular but not microvascular complications in patients with type 2 diabetes
Sarcopenic obesity evaluated by dual energy X-ray absorptiometry, rather than sarcopenia or obesity alone, is associated with the macrovascular but not microvascular complications in patients with type 2 diabetes Open
Objective: The prevalence of Sarcopenic obesity (SO) is increasing, particularly with a rising trend observed in patients diagnosed with Type 2 diabetes (T2D). However, the association between SO and diabetic complications remains unclear …
View article: Nationwide survey of physicians’ familiarity and awareness of diabetes guidelines in China: a cross-sectional study
Nationwide survey of physicians’ familiarity and awareness of diabetes guidelines in China: a cross-sectional study Open
Objective This study aims to investigate physicians’ familiarity and awareness of four diabetes guidelines and their practice of the recommendations outlined in these guidelines. Design A cross-sectional study. Setting An online questionna…
View article: PAPSS2 inhibits proliferation and metastasis of papillary thyroid cancer cells by mediating ferroptosis and disulfidptosis through the AKT signaling pathway
PAPSS2 inhibits proliferation and metastasis of papillary thyroid cancer cells by mediating ferroptosis and disulfidptosis through the AKT signaling pathway Open
Papillary thyroid cancer (PTC) is the most common type of thyroid cancer(Derwich, Sykutera et al. 2023). Unfortunately, lymph node metastasis often occur in early stage of PTC, while the specific mechanism is still unclear(Wei, Wei et al. …
View article: Identifying a distinct fibrosis subset of NAFLD via molecular profiling and the involvement of profibrotic macrophages
Identifying a distinct fibrosis subset of NAFLD via molecular profiling and the involvement of profibrotic macrophages Open
Background There are emerging studies suggesting that non-alcoholic fatty liver disease (NAFLD) is a heterogeneous disease with multiple etiologies and molecular phenotypes. Fibrosis is the key process in NAFLD progression. In this study, …
View article: Corrigendum: Shu-Xie decoction alleviates oxidative stress and colon injury in acute sleep-deprived mice by suppressing p62/KEAP1/NRF2/HO1/NQO1 signaling
Corrigendum: Shu-Xie decoction alleviates oxidative stress and colon injury in acute sleep-deprived mice by suppressing p62/KEAP1/NRF2/HO1/NQO1 signaling Open
[This corrects the article DOI: 10.3389/fphar.2023.1107507.].
View article: Dietary intakes of women with gestational diabetes mellitus and pregnancy outcomes: a prospective observational study
Dietary intakes of women with gestational diabetes mellitus and pregnancy outcomes: a prospective observational study Open
Background Nutritient intake of pregnant women with gestational diabetes mellitus (GDM) is important to ensure satisfactory birth outcomes. The aim of this study is to explore the dietary profiles of patients with GDM, compare the results …
View article: Shu-Xie decoction alleviates oxidative stress and colon injury in acute sleep-deprived mice by suppressing p62/KEAP1/NRF2/HO1/NQO1 signaling
Shu-Xie decoction alleviates oxidative stress and colon injury in acute sleep-deprived mice by suppressing p62/KEAP1/NRF2/HO1/NQO1 signaling Open
Introduction: Sleep disorders are common clinical psychosomatic disorders that can co-exist with a variety of conditions. In humans and animal models, sleep deprivation (SD) is closely related with gastrointestinal diseases. Shu-Xie Decoct…
View article: Corrigendum: Role of aerobic exercise in ameliorating NASH: Insights into the hepatic thyroid hormone signaling and circulating thyroid hormones
Corrigendum: Role of aerobic exercise in ameliorating NASH: Insights into the hepatic thyroid hormone signaling and circulating thyroid hormones Open
[This corrects the article DOI: 10.3389/fendo.2022.1075986.].
View article: Single-cell transcriptomics of hepatic stellate cells uncover crucial pathways and key regulators involved in non-alcoholic steatohepatitis
Single-cell transcriptomics of hepatic stellate cells uncover crucial pathways and key regulators involved in non-alcoholic steatohepatitis Open
Background Fibrosis is an important pathological process in the development of non-alcoholic steatohepatitis (NASH), and the activation of hepatic stellate cell (HSC) is a central event in liver fibrosis. However, the transcriptomic change…
View article: Role of aerobic exercise in ameliorating NASH: Insights into the hepatic thyroid hormone signaling and circulating thyroid hormones
Role of aerobic exercise in ameliorating NASH: Insights into the hepatic thyroid hormone signaling and circulating thyroid hormones Open
Aim Triiodothyronine (T3) administration significantly eliminates hepatic steatosis and also has a therapeutic effect on non-alcoholic steatohepatitis (NASH). However, the potential mechanism by which T3-mediated exercise improves NASH is …
View article: Novel Loss-of-Function Variant in HNF1a Induces β-Cell Dysfunction through Endoplasmic Reticulum Stress
Novel Loss-of-Function Variant in HNF1a Induces β-Cell Dysfunction through Endoplasmic Reticulum Stress Open
Heterozygous variants in the hepatocyte nuclear factor 1a (HNF1a) cause MODY3 (maturity-onset diabetes of the young, type 3). In this study, we found a case of novel HNF1a p.Gln125* (HNF1a-Q125ter) variant clinically. However, the molecula…
View article: <i>N</i><scp>‐Acetylcysteine</scp> protects against cobalt chloride‐induced endothelial dysfunction by enhancing glucose‐6‐phosphate dehydrogenase activity
<i>N</i><span>‐Acetylcysteine</span> protects against cobalt chloride‐induced endothelial dysfunction by enhancing glucose‐6‐phosphate dehydrogenase activity Open
Hypoxia‐induced endothelial dysfunction is known to be involved in the pathogenesis of several vascular diseases. However, it remains unclear whether the pentose phosphate pathway (PPP) is involved in regulating the response of endothelial…
View article: Shuxie-1 Decoction Alleviated CUMS -Induced Liver Injury via IL-6/JAK2/STAT3 Signaling
Shuxie-1 Decoction Alleviated CUMS -Induced Liver Injury via IL-6/JAK2/STAT3 Signaling Open
Introduction: Chronic stress has been shown to cause liver damage in addition to psychological depression. Besides, drug-induced liver injury is frequently caused by antidepressants. Shuxie-1 decoction (SX-1) is a formula of traditional Ch…
View article: Visceral Adipose Tissue Indices Independently Correlated with Obstructive Sleep Apnea in Patients with Type 2 Diabetes
Visceral Adipose Tissue Indices Independently Correlated with Obstructive Sleep Apnea in Patients with Type 2 Diabetes Open
Aims. We aimed to explore whether visceral adiposity indices were significantly associated with obstructive sleep apnea (OSA) in type 2 diabetes (T2DM) patients. Methods. 100 patients with T2DM who underwent overnight polysomnography were …
View article: Association between intrahepatic triglyceride content in subjects with metabolically healthy abdominal obesity and risks of pre-diabetes plus diabetes: an observational study
Association between intrahepatic triglyceride content in subjects with metabolically healthy abdominal obesity and risks of pre-diabetes plus diabetes: an observational study Open
Objective We aimed to evaluate the association of intrahepatic triglyceride (IHTG) content in subjects with metabolically healthy abdominal obesity (MHAO) on risks of pre-diabetes plus diabetes. Design Cross-sectional survey. Setting Lianq…
View article: Interleukin-6 mediated exercise-induced alleviation of adiposity and hepatic steatosis in mice
Interleukin-6 mediated exercise-induced alleviation of adiposity and hepatic steatosis in mice Open
Introduction Exercise training has been shown to be the most effective strategy to combat obesity and non-alcoholic fatty liver disease. However, exercise promotes loss of adipose tissue mass and improves obesity-related hepatic steatosis …