Explanipedia

The Breakthrough discoveries for thriving with bipolar disorder (BD2) Integrated Network Longitudinal Cohort Protocol Open

Emily G. Baxi, Meg Shanahan, Dániel Pham, Victoria Simpson Beck, Kelsey M. Barcomb , et al. · 2025

Bipolar Disorder (BD) is a highly complex and heterogeneous disorder. As such, accurate diagnosis is often delayed, and effective treatment options are limited. The Integrated Network, a program of Breakthrough Discoveries for thriving wit…

BD2: A roadmap for learning health networks driving care improvement in bipolar disorder Open

Samuel T. Savitz, Jessica M. Lipschitz, Katherine E. Burdick, Angie Ho Yan Lam, Megan Shanahan , et al. · 2025

Lessons learned include the value of lived experience stakeholder input to shape the LHN and the need to navigate challenges in identifying common measures. This work provides a roadmap for advancing bipolar disorder treatment.

Supercharging collaboration for bipolar research—Breakthrough discoveries for thriving with bipolar disorder (BD2) Open

Cara M. Altimus, Emily G. Baxi, Mark A. Frye, Eric J. Nestler, Dániel Pham , et al. · 2023

CMA, EGB, EJN, and DLP have nothing to disclose. MAF receives grant support from Assurex Health; honoraria from Carnot Laboratories and American Physician Institute; and has a financial interest in Chymia LLC. KEB receives honoraria from M…

Predictors of Functional Impairment in Bipolar Disorder: Results From 13 Cohorts From Seven Countries by the Global Bipolar Cohort Collaborative Open

Katherine E. Burdick, Caitlin E. Millett, Anastasia K. Yocum, Cara M. Altimus, Ole A. Andreassen , et al. · 2023

The bipolar clinical research community is poised to work together to characterize the multi-dimensional contributors to impairment and address the barriers that impede patients' complete recovery. We must also identify the core features w…

Editorial: Advances in understanding the nature and features of misophonia Open

M. Zachary Rosenthal, Julia Campbell, Cara M. Altimus · 2023

EDITORIAL article Front. Neurosci., 12 September 2023Sec. Auditory Cognitive Neuroscience Volume 17 - 2023 | https://doi.org/10.3389/fnins.2023.1267682

Predictors of functional impairment in bipolar disorder: Results from 13 cohorts from seven countries by the global bipolar cohort collaborative Open

Katherine E. Burdick, Caitlin E. Millett, Anastasia K. Yocum, Cara M. Altimus, Ole A. Andreassen , et al. · 2022

Objectives Persistent functional impairment is common in bipolar disorder (BD) and is influenced by a number of demographic, clinical, and cognitive features. The goal of this project was to estimate and compare the influence of key factor…

Consensus Definition of Misophonia: A Delphi Study Open

Susan E. Swedo, David Baguley, Damiaan Denys, Laura J. Dixon, Mercede Erfanian , et al. · 2022

Misophonia is a disorder of decreased tolerance to specific sounds or their associated stimuli that has been characterized using different language and methodologies. The absence of a common understanding or foundational definition of miso…

Building brain capital Open

Harris A. Eyre, Rym Ayadi, William Ellsworth, Gowri Aragam, Erin Smith , et al. · 2021

Corrigendum to “Translating big data to better treatment in bipolar disorder - a manifesto for coordinated action [European Neuropsychopharmacology (2020) 36, 121–136]” Open

Mirko Manchia, Eduard Vieta, Olav B. Smeland, Cara M. Altimus, Andreas Bechdolf , et al. · 2021

A Brain Capital Grand Strategy: toward economic reimagination Open

Erin Smith, Diab Ali, Bill Wilkerson, Walter D Dawson, Kunmi Sobowale , et al. · 2020

What we learn about bipolar disorder from large‐scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group Open

Christopher R. K. Ching, Derrek P. Hibar, Tiril P. Gurholt, Abraham Nunes, Sophia I. Thomopoulos , et al. · 2020

MRI‐derived brain measures offer a link between genes, the environment and behavior and have been widely studied in bipolar disorder (BD). However, many neuroimaging studies of BD have been underpowered, leading to varied results and uncer…

Translating big data to better treatment in bipolar disorder - a manifesto for coordinated action Open

Mirko Manchia, Eduard Vieta, Olav B. Smeland, Cara M. Altimus, Andreas Bechdolf , et al. · 2020

The Next 50 Years of Neuroscience Open

Cara M. Altimus, Bianca Jones Marlin, Naomi Charalambakis, Alexandra Colón-Rodríguez, Elizabeth J. Glover , et al. · 2020

On the 50th anniversary of the Society for Neuroscience, we reflect on the remarkable progress that the field has made in understanding the nervous system, and look forward to the contributions of the next 50 years. We predict a substantia…

Distinct ipRGC subpopulations mediate light’s acute and circadian effects on body temperature and sleep Open

Alan C. Rupp, Michelle Ren, Cara M. Altimus, Diego C. Fernandez, Melissa Richardson , et al. · 2019

The light environment greatly impacts human alertness, mood, and cognition by both acute regulation of physiology and indirect alignment of circadian rhythms. These processes require the melanopsin-expressing intrinsically photosensitive r…

Author response: Distinct ipRGC subpopulations mediate light’s acute and circadian effects on body temperature and sleep Open

Alan C. Rupp, Michelle Ren, Cara M. Altimus, Diego C. Fernandez, Melissa Richardson , et al. · 2019

Article Figures and data Abstract eLife digest Introduction Results Discussion Materials and methods Data availability References Decision letter Author response Article and author information Metrics Abstract The light environment greatly…

Distinct ipRGC subpopulations mediate light's acute and circadian effects on body temperature and sleep Open

Alan C. Rupp, Michelle Ren, Cara M. Altimus, Diego C. Fernandez, Melissa Richardson , et al. · 2018

The light environment greatly impacts human alertness, mood, and cognition by acute regulation of physiology and indirect alignment of circadian rhythms. Both processes require the melanopsin-expressing intrinsically photosensitive retinal…

Neuroscience Has the Power to Change the Criminal Justice System Open

Cara M. Altimus · 2017

As a neuroscientist working in the Department of Justice for the past year, I observed that many of the challenges of crime and justice have solutions rooted in our understanding of neuroscience. However, the neuroscience community seems a…

Abnormal wake/sleep pattern in a novel gain-of-function model of DISC1 Open

Hanna Jaaro-Peled, Cara M. Altimus, Tara A. LeGates, Tyler Cash-Padgett, Sandra Zoubovsky , et al. · 2016

Disordered Ripples Are a Common Feature of Genetically Distinct Mouse Models Relevant to Schizophrenia Open

Cara M. Altimus, Jon B. Harrold, Hanna Jaaro-Peled, Akira Sawa, David J. Foster · 2015

We present results from a novel comparative approach to the study of the mechanisms of psychiatric disease. Previous work has examined neural activity patterns in the hippocampus of a freely behaving mouse model associated with schizophren…

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