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View article: The tiny germline chromosomes of Paramecium aurelia have an exceptionally high recombination rate and are capped by a new class of Helitrons
The tiny germline chromosomes of Paramecium aurelia have an exceptionally high recombination rate and are capped by a new class of Helitrons Open
Background. Paramecia belong to the ciliate phylum of unicellular eukaryotes characterized by nuclear dimorphism. A diploid germline micronucleus (MIC) transmits genetic information across sexual generations. A polyploid transcriptionally …
View article: A histone methyltransferase-independent function of PRC2 controls small RNA dynamics during programmed DNA elimination in <i>Paramecium</i>
A histone methyltransferase-independent function of PRC2 controls small RNA dynamics during programmed DNA elimination in <i>Paramecium</i> Open
To limit transposable element (TE) mobilization, most eukaryotes have evolved small RNAs to silence TE activity via homology-dependent mechanisms. Small RNAs, 20–30 nucleotides in length, bind to PIWI proteins and guide them to nascent tra…
View article: A histone methyltransferase-independent function of PRC2 controls small RNA dynamics during programmed DNA elimination in Paramecium
A histone methyltransferase-independent function of PRC2 controls small RNA dynamics during programmed DNA elimination in Paramecium Open
To limit transposable element (TE) mobilization, most eukaryotes have evolved small RNAs to silence TE activity via homology-dependent mechanisms. Small RNAs, 20-30 nucleotides in length, bind to PIWI proteins and guide them to nascent tra…
View article: Validation of a DIVA qPCR Duplex Assay to Differentiate Primun Salmonella T Vaccine from Salmonella enterica subsp. enterica Serovar Typhimurium Wild Strains
Validation of a DIVA qPCR Duplex Assay to Differentiate Primun Salmonella T Vaccine from Salmonella enterica subsp. enterica Serovar Typhimurium Wild Strains Open
Salmonella enterica subsp. enterica serovar Typhimurium is an important foodborne pathogen, and poultry products are a major source of human infection. Live attenuated vaccines for poultry are an effective tool for reducing the prevalence …
View article: Identification of Listeria Isolates by Using a Pragmatic Multilocus Phylogenetic Analysis
Identification of Listeria Isolates by Using a Pragmatic Multilocus Phylogenetic Analysis Open
Species identification of Listeria isolates remained a tedious process still based on culturing methods that, in recent years, have led to the description of many species that are not even part of the genus Listeria. It is advisable to pro…
View article: Non-catalytic function of PRC2 in the control of small RNA dynamics during programmed genome elimination in Paramecium
Non-catalytic function of PRC2 in the control of small RNA dynamics during programmed genome elimination in Paramecium Open
To limit transposable element (TE) mobilization, most eukaryotes have evolved small RNAs to silence TE activity via homology-dependent mechanisms. Small RNAs, 20-30 nucleotides in length, bind to PIWI proteins and guide them to nascent tra…
View article: Non-catalytic function of PRC2 in the control of small RNA dynamics during programmed genome elimination in Paramecium
Non-catalytic function of PRC2 in the control of small RNA dynamics during programmed genome elimination in Paramecium Open
To limit transposable element (TE) mobilization, most eukaryotes have evolved small RNAs to silence TE activity via homology-dependent mechanisms. Small RNAs, 20-30 nucleotides in length, guide PIWI proteins to which they bind, to nascent …
View article: A histone methyltransferase-independent function of PRC2 controls small RNA dynamics during programmed DNA elimination in <i>Paramecium</i>
A histone methyltransferase-independent function of PRC2 controls small RNA dynamics during programmed DNA elimination in <i>Paramecium</i> Open
To limit transposable element (TE) mobilization, most eukaryotes have evolved small RNAs to silence TE activity via homology-dependent mechanisms. Small RNAs, 20-30 nucleotides in length, bind to PIWI proteins and guide them to nascent tra…
View article: Paramecium Polycomb repressive complex 2 physically interacts with the small RNA-binding PIWI protein to repress transposable elements
Paramecium Polycomb repressive complex 2 physically interacts with the small RNA-binding PIWI protein to repress transposable elements Open
View article: Paramecium Polycomb Repressive Complex 2 physically interacts with the small RNA binding PIWI protein to repress transposable elements
Paramecium Polycomb Repressive Complex 2 physically interacts with the small RNA binding PIWI protein to repress transposable elements Open
Polycomb Repressive Complex 2 (PRC2) maintains transcriptionally silent genes in a repressed state via deposition of histone H3 K27 trimethyl (me3) marks. PRC2 has also been implicated in silencing transposable elements (TEs), yet how PRC2…
View article: Paramecium Polycomb Repressive Complex 2 physically interacts with the small RNA binding PIWI protein to repress transposable elements
Paramecium Polycomb Repressive Complex 2 physically interacts with the small RNA binding PIWI protein to repress transposable elements Open
Polycomb Repressive Complex 2 (PRC2) maintains transcriptionally silent genes in a repressed state via deposition of histone H3 K27 trimethyl (me3) marks. PRC2 has also been implicated in silencing transposable elements (TEs), yet how PRC2…
View article: Paramecium Polycomb Repressive Complex 2 physically interacts with the small RNA binding PIWI protein to repress transposable elements
Paramecium Polycomb Repressive Complex 2 physically interacts with the small RNA binding PIWI protein to repress transposable elements Open
Polycomb Repressive Complex 2 (PRC2) maintains transcriptionally silent genes in a repressed state via deposition of histone H3 K27 trimethyl (me3) marks. PRC2 has also been implicated in silencing transposable elements (TEs), yet how PRC2…
View article: <i>Paramecium</i> Polycomb Repressive Complex 2 physically interacts with the small RNA binding PIWI protein to repress transposable elements
<i>Paramecium</i> Polycomb Repressive Complex 2 physically interacts with the small RNA binding PIWI protein to repress transposable elements Open
SUMMARY Polycomb Repressive Complex 2 (PRC2) maintains transcriptionally silent genes in a repressed state via deposition of histone H3 K27 trimethyl (me3) marks. PRC2 has also been implicated in silencing transposable elements (TEs) yet h…
View article: The Paramecium PRC2 complex physically interacts with the RNAi pathway
The Paramecium PRC2 complex physically interacts with the RNAi pathway Open
In addition to its role in the transcriptional repression of protein-coding genes, the Polycomb Repressive Complex 2 (PRC2) and its H3K27me3 activity silence transposable elements in diverse eukaryotes. How PRC2 is tethered to transposable…
View article: Characterization of the histone methyltransferase Ezl1 of Paramecium tetraurelia and identification of its protein partners
Characterization of the histone methyltransferase Ezl1 of Paramecium tetraurelia and identification of its protein partners Open
In eukaryotic genomes, chromatin structure defines and maintains active and silent transcriptional states. Histone post-translational modifications can alter chromatin structure and thus, have an essential role in dictating its transcripti…
View article: The Polycomb protein Ezl1 mediates H3K9 and H3K27 methylation to repress transposable elements in Paramecium
The Polycomb protein Ezl1 mediates H3K9 and H3K27 methylation to repress transposable elements in Paramecium Open