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View article: Method development and validation for quantitative determination of urinary biomarkers of food intake for multiple foods
Method development and validation for quantitative determination of urinary biomarkers of food intake for multiple foods Open
Biomarkers of food intake (BFIs) have emerged as a promising objective tool to complement traditional self-reported dietary assessment in nutritional research, with the potential to reduce systematic errors and improve accuracy. The develo…
View article: Acute effects of moderate vs. vigorous endurance exercise on urinary metabolites in healthy, young, physically active men—A multi-platform metabolomics approach
Acute effects of moderate vs. vigorous endurance exercise on urinary metabolites in healthy, young, physically active men—A multi-platform metabolomics approach Open
Introduction: Endurance exercise alters whole-body as well as skeletal muscle metabolism and physiology, leading to improvements in performance and health. However, biological mechanisms underlying the body’s adaptations to different endur…
View article: Combined Untargeted and Targeted Fingerprinting by Comprehensive Two-Dimensional Gas Chromatography to Track Compositional Changes on Hazelnut Primary Metabolome during Roasting
Combined Untargeted and Targeted Fingerprinting by Comprehensive Two-Dimensional Gas Chromatography to Track Compositional Changes on Hazelnut Primary Metabolome during Roasting Open
This study focuses on the detectable metabolome of high-quality raw hazelnuts (Corylus avellana L.) and on its changes after dry-roasting. Informative fingerprinting was obtained by comprehensive two-dimensional gas chromatography with fas…
View article: Identification of markers for dietary intake and health status by GC-MS based metabolite profiling approaches
Identification of markers for dietary intake and health status by GC-MS based metabolite profiling approaches Open
Markers are compounds that can be used as indicators of an exposure, a metabolic state, or any other effect. Metabolomics and metabolite profiling approaches for marker discovery will increasingly gain significance. In the context of food,…
View article: Exploring the Diversity of Sugar Compounds in Healthy, Prediabetic, and Diabetic Volunteers
Exploring the Diversity of Sugar Compounds in Healthy, Prediabetic, and Diabetic Volunteers Open
Scope Diabetes is thought to primarily represent a disturbance of carbohydrate metabolism; however, population studies employing metabolomics have mainly identified plasma amino acids and lipids, or their products, as biomarkers. In this p…
View article: The Putative Caloric Restriction Mimetic Resveratrol has Moderate Impact on Insulin Sensitivity, Body Composition, and the Metabolome in Mice
The Putative Caloric Restriction Mimetic Resveratrol has Moderate Impact on Insulin Sensitivity, Body Composition, and the Metabolome in Mice Open
Scope Data on resveratrol‐( trans ‐3,5,4′‐trihydroxystilbene)‐induced caloric‐restriction‐(CR)‐mimicking effects in mice receiving a high‐fat diet (HFD) are contradictory. It is hypothesized that this can possibly stem from different bioac…
View article: Discovery and Validation of Banana Intake Biomarkers Using Untargeted Metabolomics in Human Intervention and Cross-sectional Studies
Discovery and Validation of Banana Intake Biomarkers Using Untargeted Metabolomics in Human Intervention and Cross-sectional Studies Open
View article: Robust Markers of Coffee Consumption Identified Among the Volatile Organic Compounds in Human Urine
Robust Markers of Coffee Consumption Identified Among the Volatile Organic Compounds in Human Urine Open
Scope The human volatilome has gained high interest for the discovery of potential biomarkers of diseases. However, knowledge about the diet as a crucial factor affecting the volatilome is scarce. Therefore, the search for disease biomarke…
View article: Applying an untargeted metabolomics approach using two complementary platforms for the discovery and validation of banana intake biomarkers
Applying an untargeted metabolomics approach using two complementary platforms for the discovery and validation of banana intake biomarkers Open
Background: Accurate assessment of dietary intake is crucial for nutritional and health research. However, the dietary assessment tools currently used, such as dietary records or food frequency questionnaires, are subject to different fact…
View article: Biomarkers of intake for coffee, tea, and sweetened beverages
Biomarkers of intake for coffee, tea, and sweetened beverages Open
Non-alcoholic beverages are important sources of nutrients and bioactive compounds that may influence human health and increase or decrease the risk of chronic diseases. A wide variety of beverage constituents are absorbed in the gut, foun…
View article: The complex human urinary sugar profile: determinants revealed in the cross-sectional KarMeN study
The complex human urinary sugar profile: determinants revealed in the cross-sectional KarMeN study Open
View article: Metabolite patterns predicting sex and age in participants of the Karlsruhe Metabolomics and Nutrition (KarMeN) study
Metabolite patterns predicting sex and age in participants of the Karlsruhe Metabolomics and Nutrition (KarMeN) study Open
Physiological and functional parameters, such as body composition, or physical fitness are known to differ between men and women and to change with age. The goal of this study was to investigate how sex and age-related physiological condit…