Carl D. Herickhoff
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View article: 3D-augmentation of 2D ultrasound for appendicitis diagnosis: A cross-sectional pilot study
3D-augmentation of 2D ultrasound for appendicitis diagnosis: A cross-sectional pilot study Open
Background: Two-dimensional ultrasound (2DUS) is first-line imaging for pediatric appendicitis but is often nondiagnostic. Computed tomography (CT) is expensive with ionizing radiation. Three-dimensional ultrasound (3DUS) can capture multi…
View article: Passive Cavitation Mapping by Cavitation Source Localization From Aperture-Domain Signals—Part II: Phantom and In Vivo Experiments
Passive Cavitation Mapping by Cavitation Source Localization From Aperture-Domain Signals—Part II: Phantom and In Vivo Experiments Open
Passive cavitation mapping (PCM) techniques typically utilize a time-exposure acoustic (TEA) approach, where the received radio frequency data are beamformed, squared, and integrated over time. Such PCM-TEA cavitation maps typically suffer…
View article: Nondestructive Detection of Targeted Microbubbles Using Dual-Mode Data and Deep Learning for Real-Time Ultrasound Molecular Imaging
Nondestructive Detection of Targeted Microbubbles Using Dual-Mode Data and Deep Learning for Real-Time Ultrasound Molecular Imaging Open
Ultrasound molecular imaging (UMI) is enabled by targeted microbubbles (MBs), which are highly reflective ultrasound contrast agents that bind to specific biomarkers. Distinguishing between adherent MBs and background signals can be challe…
View article: Extending Retrospective Encoding for Robust Recovery of the Multistatic Data Set
Extending Retrospective Encoding for Robust Recovery of the Multistatic Data Set Open
Robust recovery of multistatic synthetic aperture data from conventional ultrasound sequences can enable complete transmit-and-receive focusing at all points in the field of view without the drawbacks of virtual-source synthetic aperture a…
View article: Unsupervised clustering method to convert high-resolution magnetic resonance volumes to three-dimensional acoustic models for full-wave ultrasound simulations
Unsupervised clustering method to convert high-resolution magnetic resonance volumes to three-dimensional acoustic models for full-wave ultrasound simulations Open
Simulations of acoustic wave propagation, including both the forward and the backward propagations of the wave (also known as full-wave simulations), are increasingly utilized in ultrasound imaging due to their ability to more accurately m…
View article: Ultrasound- and microbubble-mediated targeted delivery of therapeutic microRNA-loaded nanocarriers to deep liver and kidney tissues in pigs
Ultrasound- and microbubble-mediated targeted delivery of therapeutic microRNA-loaded nanocarriers to deep liver and kidney tissues in pigs Open
In this study, we designed and validated a platform for ultrasound (US) and microbubble (MB)-mediated delivery of FDA-approved pegylated poly lactic-co-glycolic acid (PLGA) nanoparticles (NPs) loaded with anticancer microRNAs (miRNAs) to d…