Carl Granath
YOU?
Author Swipe
View article: SPP1/osteopontin: a driver of fibrosis and inflammation in degenerative ascending aortic aneurysm?
SPP1/osteopontin: a driver of fibrosis and inflammation in degenerative ascending aortic aneurysm? Open
Degenerative ascending aortic aneurysm (AscAA) is a silent and potentially fatal disease characterized by excessive vascular inflammation and fibrosis. We aimed to characterize the cellular and molecular signature for the fibrotic type of …
View article: Possible Role of SPP1 in Degenerative Ascending Aortic Aneurysm Formation
Possible Role of SPP1 in Degenerative Ascending Aortic Aneurysm Formation Open
Background: Ascending aortic aneurysm (AscAA) is a silent, progressive and potentially fatal disease. AscAA is characterized by excessive fibrosis and inflammation, but the underlying molecular mechanism is not well established. Our object…
View article: ASA is Associated with A Lower Prevalence of Ascending Aortic Aneurysm and A Decreased Aortic Expression of COX2
ASA is Associated with A Lower Prevalence of Ascending Aortic Aneurysm and A Decreased Aortic Expression of COX2 Open
Background: Acetylsalicylic acid (ASA) therapy has been associated with a reduced prevalence and growth rate of abdominal as well as intracranial aneurysms, but the relationship between ASA and ascending aortic aneurysm (AscAA) formation r…
View article: Valve disease and aortopathy associations of bicuspid aortic valve phenotypes differ between men and women
Valve disease and aortopathy associations of bicuspid aortic valve phenotypes differ between men and women Open
Objective Determine whether associations between bicuspid aortic valve (BAV) phenotypes, valve disease and aortopathy differ between sexes. Methods 1045 patients with BAV (76.0% men, n=794) from two surgical centres were included in this c…
View article: Characterization of Laminins in Healthy Human Aortic Valves and a Modified Decellularized Rat Scaffold
Characterization of Laminins in Healthy Human Aortic Valves and a Modified Decellularized Rat Scaffold Open
Aortic valve stenosis is one of the most common cardiovascular diseases in western countries and can only be treated by replacement with a prosthetic valve. Tissue engineering is an emerging and promising treatment option, but in-depth kno…