Carl Lachat
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View article: Prevalence of Large‐for‐Gestational Age and Macrosomia Among Livebirths in 23 Low‐ and Middle‐Income Countries Between 2000 and 2021: An Individual Participant Data Analysis
Prevalence of Large‐for‐Gestational Age and Macrosomia Among Livebirths in 23 Low‐ and Middle‐Income Countries Between 2000 and 2021: An Individual Participant Data Analysis Open
Objective To examine the prevalence of large‐for‐gestational age (LGA) and macrosomia in 23 countries between 2000 and 2021. Design Descriptive multi‐country secondary data analysis. Setting Subnational, population‐based cohort studies ( k…
View article: Long-Term Effects of Multiple Micronutrient Supplementation During Pregnancy, Lactation, and Early Childhood on the Cognitive Development of Children Aged 4 –14 Years: A Systematic Review of Randomized Controlled Trials
Long-Term Effects of Multiple Micronutrient Supplementation During Pregnancy, Lactation, and Early Childhood on the Cognitive Development of Children Aged 4 –14 Years: A Systematic Review of Randomized Controlled Trials Open
Background: Inadequate nutrition, poor health care, and limited stimulation constrain early childhood development and cognitive potential. Micronutrient deficiencies during pregnancy and early life are prevalent in low- and middle-income c…
View article: The human milk microbiome varies by environmental factors and is associated with infant growth: findings from the IMiC Consortium
The human milk microbiome varies by environmental factors and is associated with infant growth: findings from the IMiC Consortium Open
Human milk (HM) is a complex ecological matrix that connects mothers and infants to the surrounding environment, and promotes infant growth and health. While certain components of HM are well studied, including its macronutrient content an…
View article: Perceptions and practices in urban Burkina Faso: a qualitative study on gestational age estimation among health workers
Perceptions and practices in urban Burkina Faso: a qualitative study on gestational age estimation among health workers Open
Standardized gestational age estimation and improved data recording can enhance preterm birth surveillance and help reduce neonatal mortality in low-resource settings.
View article: Ocean for Health: A Transdisciplinary Framework to Accelerate Research on Ocean–Human Health Connections
Ocean for Health: A Transdisciplinary Framework to Accelerate Research on Ocean–Human Health Connections Open
The ocean has an important impact on human health. Observational studies suggest that ocean-related stimuli can improve human health, but there is limited research investigating the underlying mechanistic and epidemiological principles. Re…
View article: Off-farm income and dietary diversity in subsistence farming in Burundi
Off-farm income and dietary diversity in subsistence farming in Burundi Open
View article: Effect of intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine on maternal gestational weight gain in low-income and middle-income countries: a systematic review and individual participant data meta-analysis of randomised clinical trials
Effect of intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine on maternal gestational weight gain in low-income and middle-income countries: a systematic review and individual participant data meta-analysis of randomised clinical trials Open
View article: Contribution of Maternal Adherence to the Effect of Multiple Micronutrient Supplementation During Pregnancy: A Systematic Review and Individual Participant Data Meta-analysis
Contribution of Maternal Adherence to the Effect of Multiple Micronutrient Supplementation During Pregnancy: A Systematic Review and Individual Participant Data Meta-analysis Open
Multiple micronutrient supplements (MMS) in pregnancy reduces risk of infant low birthweight (LBW) and improves other maternal and infant outcomes compared with iron and folic acid (IFA) supplements alone. However, the impact of timing of …
View article: The Effect of Balanced Energy-Protein Supplementation Provided to Pregnant Women on Infant Birth Weight: An Individual Participant Data Meta-Analysis
The Effect of Balanced Energy-Protein Supplementation Provided to Pregnant Women on Infant Birth Weight: An Individual Participant Data Meta-Analysis Open
View article: Effect of prenatal multiple micronutrient supplementation compared with iron and folic acid supplementation on size at birth and subsequent growth through 24 mo of age: a systematic review and meta-analysis
Effect of prenatal multiple micronutrient supplementation compared with iron and folic acid supplementation on size at birth and subsequent growth through 24 mo of age: a systematic review and meta-analysis Open
Prenatal MMS improves size at birth and subsequent infant growth through 6 mo of age but not thereafter. These results strengthen the evidence on MMS benefits beyond birth outcomes. This study was registered in PROSPERO as CRD42024551864.
View article: Infant-level and child-level predictors of mortality in low-resource settings: the WHO Child Mortality Risk Stratification Multi-Country Pooled Cohort
Infant-level and child-level predictors of mortality in low-resource settings: the WHO Child Mortality Risk Stratification Multi-Country Pooled Cohort Open
For the Spanish and French translations of the abstract see Supplementary Materials section.
View article: Understanding the factors associated with child malnutrition in rural Burundi: experiences from the Muyinga and Ngozi provinces
Understanding the factors associated with child malnutrition in rural Burundi: experiences from the Muyinga and Ngozi provinces Open
Background: Childhood stunting, wasting, and underweight are markers of poor nutrition and socioeconomic deprivation in low-income countries. It remains unclear which factors are associated with child malnutrition in rural Burundi, in part…
View article: Incidence and mortality of acute aflatoxicosis: A systematic review
Incidence and mortality of acute aflatoxicosis: A systematic review Open
View article: Maternal balanced energy-protein supplementation reshapes the maternal gut microbiome and enhances carbohydrate metabolism in infants: a randomized controlled trial
Maternal balanced energy-protein supplementation reshapes the maternal gut microbiome and enhances carbohydrate metabolism in infants: a randomized controlled trial Open
View article: Comparison of Gestational Age Assessment Methods in the Second and Third Trimesters: Evaluating Alternative Approaches Against Ultrasound in Urban Burkina Faso
Comparison of Gestational Age Assessment Methods in the Second and Third Trimesters: Evaluating Alternative Approaches Against Ultrasound in Urban Burkina Faso Open
Background: Accurate determination of gestational age by way of ultrasound is challenging in resource-limited settings like Burkina Faso, leading to the use of alternative methods, though their accuracy and agreement remain poorly establis…
View article: The effect of prenatal balanced energy and protein supplementation on gestational weight gain: An individual participant data meta-analysis in low- and middle-income countries
The effect of prenatal balanced energy and protein supplementation on gestational weight gain: An individual participant data meta-analysis in low- and middle-income countries Open
Background Understanding the effects of balanced energy and protein (BEP) supplements on gestational weight gain (GWG) and how the effects differ depending on maternal characteristics and the nutritional composition of the supplements will…
View article: Delphi survey to gather feedback on a CONSORT extension proposal for nutrition intervention trials
Delphi survey to gather feedback on a CONSORT extension proposal for nutrition intervention trials Open
View article: Author Correction: Burdens of type 2 diabetes and cardiovascular disease attributable to sugar-sweetened beverages in 184 countries
Author Correction: Burdens of type 2 diabetes and cardiovascular disease attributable to sugar-sweetened beverages in 184 countries Open
View article: Burdens of type 2 diabetes and cardiovascular disease attributable to sugar-sweetened beverages in 184 countries
Burdens of type 2 diabetes and cardiovascular disease attributable to sugar-sweetened beverages in 184 countries Open
View article: Quantifying the environmental and food biodiversity impacts of ultra-processed foods: evidence from the European Prospective Investigation into Cancer and Nutrition (EPIC) study
Quantifying the environmental and food biodiversity impacts of ultra-processed foods: evidence from the European Prospective Investigation into Cancer and Nutrition (EPIC) study Open
Objective: While associations of ultra-processed food (UPF) consumption with adverse health outcomes are accruing, its environmental and food biodiversity impacts remain underexplored. This study examines associations between UPF consumpti…
View article: Describing Biological Vulnerability in Small, Vulnerable Newborns in Urban Burkina Faso (DenBalo): Gut Microbiota, Immune System, and Breastmilk Assembly
Describing Biological Vulnerability in Small, Vulnerable Newborns in Urban Burkina Faso (DenBalo): Gut Microbiota, Immune System, and Breastmilk Assembly Open
Background: Small vulnerable newborns (SVNs), including those born preterm, small for gestational age, or with low birth weight, are at higher risk of neonatal mortality and long-term health complications. Early exposure to maternal vagina…
View article: Risk ranking of mycotoxins in plant-based meat and dairy alternatives under protein transition scenarios
Risk ranking of mycotoxins in plant-based meat and dairy alternatives under protein transition scenarios Open
View article: The Minimum Dietary Diversity For Women Indicator Can Be Extended To Children And Adolescents aged 4-15 Years As A Proxy Population Indicator For Good Micronutrient Adequacy Of Diets In Low- and Middle-Income Countries
The Minimum Dietary Diversity For Women Indicator Can Be Extended To Children And Adolescents aged 4-15 Years As A Proxy Population Indicator For Good Micronutrient Adequacy Of Diets In Low- and Middle-Income Countries Open
View article: Ochratoxin A Status at Birth Is Associated with Reduced Birth Weight and Ponderal Index in Rural Burkina Faso
Ochratoxin A Status at Birth Is Associated with Reduced Birth Weight and Ponderal Index in Rural Burkina Faso Open
View article: Rapid LA-REIMS-based metabolic fingerprinting of serum discriminates aflatoxin-exposed from non-exposed pregnant women: a prospective cohort from the Butajira Nutrition, Mental Health, and Pregnancy (BUNMAP) Study in rural Ethiopia
Rapid LA-REIMS-based metabolic fingerprinting of serum discriminates aflatoxin-exposed from non-exposed pregnant women: a prospective cohort from the Butajira Nutrition, Mental Health, and Pregnancy (BUNMAP) Study in rural Ethiopia Open
To date, the changes in maternal metabolic response associated with prenatal aflatoxin exposure remain largely unknown. This study investigated the effects of prenatal aflatoxin exposure on the maternal serum metabolome in rural Ethiopia. …
View article: Clinical and biochemical responses to treatment of uncomplicated severe acute malnutrition: a multicenter observational cohort from the OptiDiag study
Clinical and biochemical responses to treatment of uncomplicated severe acute malnutrition: a multicenter observational cohort from the OptiDiag study Open
View article: Prenatal multiple micronutrient-fortified balanced energy-protein supplementation and newborn telomere length and mitochondrial DNA content: a randomized controlled efficacy trial in rural Burkina Faso
Prenatal multiple micronutrient-fortified balanced energy-protein supplementation and newborn telomere length and mitochondrial DNA content: a randomized controlled efficacy trial in rural Burkina Faso Open
Background: Evidence regarding the effectiveness of prenatal nutritional supplements has mainly considered anthropometric pregnancy outcomes. The effect on markers of health and disease, such as offspring telomere length (TL) and mitochond…
View article: Maternal Fortified Balanced Energy-Protein Supplementation Increases Diversity of the Maternal Gut Microbiome and the Capacity of Carbohydrate Uptake in Infant Gut
Maternal Fortified Balanced Energy-Protein Supplementation Increases Diversity of the Maternal Gut Microbiome and the Capacity of Carbohydrate Uptake in Infant Gut Open
View article: Balanced Energy-Protein Supplementation Package in Lactating Women Increases Anthropometric Outcomes in Mothers and Infants: A Prospective IPD Meta-Analysis
Balanced Energy-Protein Supplementation Package in Lactating Women Increases Anthropometric Outcomes in Mothers and Infants: A Prospective IPD Meta-Analysis Open
Objectives: The Maternal Balanced Energy-Protein (BEP) Studies Harmonization Initiative, a collaboration of BEP trials in Africa and Asia, aimed to assess the effect of BEP given to lactating women on maternal and infant anthropometry. Met…
View article: Co-benefits of Biodiverse Diets on Human and Planetary Health – An Analysis of the EPIC Study
Co-benefits of Biodiverse Diets on Human and Planetary Health – An Analysis of the EPIC Study Open
Background and objectives: The food system plays a pivotal role on greenhouse gas emissions, land use, as well as on population health. This study explored the relationships between food biodiversity, by means of dietary species richness (…