Carl Pollis
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View article: Next-generation large-scale binary protein interaction network for <i>Drosophila</i>
Next-generation large-scale binary protein interaction network for <i>Drosophila</i> Open
Generating reference maps of the interactome networks underlying most cellular functions can greatly illuminate genetic studies by providing a protein-centric approach to finding new components of existing pathways, complexes, and processe…
View article: A reference map of the human protein interactome
A reference map of the human protein interactome Open
Global insights into cellular organization and function require comprehensive understanding of interactome networks. Similar to how a reference genome sequence revolutionized human genetics, a reference map of the human interactome network…
View article: Network-based prediction of protein interactions
Network-based prediction of protein interactions Open
As biological function emerges through interactions between a cell’s molecular constituents, understanding cellular mechanisms requires us to catalogue all physical interactions between proteins [1–4]. Despite spectacular advances in high-…